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Temgesic Sublingual Tablets - CD

Item Number: TEMGESIC

Temgesic Sublingual Tablets - CD

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As a strong analgesic for the relief of moderate to severe pain.

Posology and method of administration
Administration by the sublingual route.

Adults and children over 12:
1-2 tablets (200-400 micrograms) to be dissolved under the tongue every 6-8 hours or as required. The recommended starting dose for moderate to severe pain of the type typically presenting in general practice is 1 to 2 tablets, 8 hourly.

There is no evidence that dosage needs to be modified for the elderly.

Children under 12 years:
Temgesic Sublingual is suitable for use in children under 12 as follows:
16-25 kg (35-55 lb) ½ tablet
25-37.5 kg (55-82.5 lb) ½ - 1 tablet
37.5-50 kg (82.5-110 lb) 1-1 ½ tablets
The recommended dose should be administered every 6-8 hours.
Sublingual administration is not suitable for children under the age of six years.
Temgesic sublingual may be used in balanced anaesthetic techniques at a dose of 400 micrograms.

Special populations
Hepatic impairment
The effects of hepatic impairment on the pharmacokinetics of buprenorphine were evaluated in a postmarketing study. Buprenorphine is extensively metabolized in the liver, and plasma levels were found to be higher for buprenorphine in patients with moderate and severe hepatic impairment compared to healthy subjects. Patients should be monitored for signs and symptoms of toxicity or overdose caused by increased levels of buprenorphine. Temgesic should be used with caution in patients with moderate to severe hepatic impairment

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