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Porcilis Glässer Suspension for injection for pigs 50ml

Item Number: PORCILISG

Porcilis Glässer Suspension for injection for pigs 50ml

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Description

Porcilis Glässer Suspension for injection for pigs 50ml, 25 Dose.

Qualitative and quantitative composition

Active substance(s) per dose of 2 ml: Inactivated whole bacterial cells of Haemophilus parasuis serotype 5, strain 4800: 0.05 mg total nitrogen, inducing = 9.1 Elisa Units*.

Adjuvant: 150 mg dl-a-tocopheryl acetate.

Excipients: For a full list of excipients, see section Pharmaceutical Particulars.

* ELISA units = mean antibody titre (log2 value) in the potency test in mice.

Pharmaceutical form

Suspension for injection.

Appearance: aqueous, white or nearly white suspension.

Clinical particulars

Target species

Pigs and sows

Indications for use

Pigs: Active immunisation of pigs to reduce typical lesions of Glässer’s disease caused by Haemophilus parasuis serotype 5.

Onset of immunity: 2 weeks after completion of vaccination.

Duration of immunity: 14 weeks after completion of vaccination.

Sows: For passive immunisation of the progeny of vaccinated sows and gilts to reduce infection, mortality, clinical signs and typical lesions of Glässer disease caused by H. parasuis serotype 5 and to reduce clinical signs and mortality caused by H. parasuis serotype 4.

Onset of immunity: After birth and sufficient uptake of colostrum.

Duration of immunity has been demonstrated at 4 weeks of age against serotype 4 and at 6 weeks of age against serotype 5.

Contra-indications

None.

Special warnings for each target species

None.

Special precautions for use

Vaccinate only healthy animals. In the event of anaphylactic reaction consult your veterinarian.

Operator warnings

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions

Pigs: A transient increase in temperature (= 2°C) in combination with signs of general discomfort, such as less activity, depression and vomiting may occur on the day of vaccination. The next day the animals are back to normal. Local reactions (painless reddish swellings of 2.5-7.5 cm) may be observed in some pigs until 3 days after vaccination. Systemic anaphylactic reactions may occur in very rare cases (e.g. less than 1 animal in 10,000 animals).

Sows: A transient increase in temperature may occur (mean 0.9°C, with individual animals displaying a temperature increase of above 2°C). A tendency to lie down, reduced feed and water intake and minor signs of illness may be observed 1 to 2 days after vaccination. All animals return to normal within 1 to 3 days after vaccination. Transient local reactions consisting mostly of non-painful swellings with a diameter smaller than 10 cm may be observed. In some cases swelling may be warm, red and painful with a size larger than 10 cm. These local reactions disappear or clearly diminish 14 days after vaccination.

Use during pregnancy, lactation or lay

Can be used during pregnancy.

Interactions

No information is available on the compatibility of this vaccine with any other. Therefore the safety and efficacy of this product when used with any other (either when used on the same day or at different times) has not been demonstrated.

Amounts to be administered and administration route

Allow vaccine to reach ambient temperature. Shake well before use. Administer 2 ml (one dose) of the vaccine intramuscularly in the neck of the pig.The vaccine is of benefit when pigs and sows with no or low levels of antibodies against H. parasuis serotype 5 are mixed with animals from or in an environment with higher prevalence of Glässers disease or if the piglets from sows with no or low antibodies are reared in such environment. Vaccination of sows with moderate to high levels of antibodies has not been shown to provide additional protection of the offspring. The control of Glässers disease is also dependent on management factors and reduction of stress. Antibodies against H. parasuis serotype 5 have been shown to be cross-reactive against H. parasuis serotype 4.

Vaccination scheme pigs: Vaccinate pigs of at least five weeks of age twice with an interval of two weeks.

Vaccination scheme sows: Vaccinate sows at 6 to 8 weeks before expected time of farrowing twice with an interval of four weeks.

Revaccination scheme sows: For sows vaccinated during the previous pregnancy, a single revaccination at 4 to 2 weeks before farrowing is recommended.

Overdose

Pigs: After vaccination with a twofold overdose, reactions are not different from those after the single dose. Sows: After vaccination with a twofold overdose, a transient increase in temperature may occur (mean 1.8 °C, with a maximum observed temperature of 41.3°C). Other reactions are not different from those after a single dose.

Withdrawal periods

Zero days.

Pharmacological particulars

Pharmacotherapeutic group: Inactivated bacterial vaccine.

ATC vet code: QI 09AB07.

Immunological properties

The product stimulates the development of active immunity against H. parasuis serotype 5. Serotype 5 is the most prevalent under the virulent serotypes of H. parasuis. There is some cross protection to the other virulent serotypes, but full cross protection cannot be assured. The product stimulates transfer of passive immunity against H. parasuis serotype 5 and 4 to the progeny after vaccination of pregnant sows. It contains an aqueous adjuvant.

Pharmaceutical particulars

Excipients

Phosphate buffer, simethicone, water for injections and polysorbate 80.

Major incompatibilities

Do not mix with any other vaccine or immunological product.

Shelf life

PET vials: 2 years and glass vials: 1 year. Use broached vials immediately.

Special precautions for storage

Store in a refrigerator (+2°C and +8°C). Do not freeze. Protect from light.

Immediate packaging

Vials of PET or Glass type I (Ph. Eur.) containing 20 ml (10 dose presentation), 50 ml (25 dose presentation) or 100 ml (50 dose presentation), closed with a halogenobutyl rubber stopper and sealed with a coded aluminium cap. Porcilis Glässer is presented in cartons containing 1, 6 or 12 vials of 20 ml, 50 ml or 100 ml. Not all pack sizes may be marketed

Disposal

Any unused product or waste material should be disposed of in accordance with national requirements.


Data Sheets

PORCILISG: Data Sheet

Delivery

Shipping charges mainland UK zone1

ValueWeightDelivery Charge
Over £49.00Any WeightFREE
Under £49.00No weight limit£4.50
Under £49.00Under 250g£2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

Returns

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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