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Panacur Liquid 10%

Item Number: PAN1L

Panacur Liquid 10%

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  • 1L

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    £ 82.99

    Web code: E1291

  • 5L

    Estimated dispatch on Monday

    £ 409.99

    Web code: E1324

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Description

A 10% suspension of fenbendazole as a ready to administer oral anthelmintic for cattle, sheep and horses. 1 ml contains 100 mg active ingredient fenbendazole.

Cattle and Horses
Administer orally approximately 1 ml per 13 kg bodyweight (= 7.5 mg fenbendazole/kg bodyweight).

Sheep
Administer orally 0.5 ml per 10 kg bodyweight (= 5 mg fenbendazole/kg bodyweight).

PANACUR LIQUID 10% contains Fenbendazole one of the benzimidazole family of wormers. As with all Panacur wormers this will treat large and small redworms.ascarids etc including intestinal larvae and eggs. It does NOT treat tapeworm nor Bots. Panacur Liquid is unflavoured and suitable for the few horses disliking Panacur Equine Guard.
An economical wormer for the larger establishment as one litre will treat around 26 average horses. If tapeworm cover is needed a double dose of  Pyrantel (Pyratape P or Strongid P) may be given at the beginning and end of the grazing season. Bots will require either
Ivermectin or moxidectin around Christmas and encysted small redworm a 5 day Panacur course
MAY BE GIVEN TO BROOD MARES.


Data Sheets

Panacur® 10 % Oral Suspension Species:Cattle, Horses and other equidae, Sheep

Therapeutic indication:Pharmaceuticals: Endoparasiticides: Anthelmintics for cattle, Anthelmintics for sheep, Anthelmintics for horses

Active ingredient:Fenbendazole

Product:Panacur® 10 % Oral Suspension

Product index:Panacur® 10 % Oral Suspension

Cattle - milk:120 hours (5 days)

Cattle - meat:12 days

Sheep - meat:15 days

Withdrawal notes:Sheep milk: 168 hours (7 days). Not to be used in horses intended for human consumption.

Qualitative and quantitative composition

Active substance % w/v

Fenbendazole: 10.00

Other substances:

Sodium methyl hydroxybenzoate: 0.200

Sodium propyl hydroxybenzoate: 0.0216

Benzyl alcohol: 0.4835

For full list of excipients, see section "Pharmaceutical Particulars".

Pharmaceutical form

Clear colourless or virtually colourless oral suspension.

Clinical particulars

Target species

Cattle, sheep, horses and other equines.

Indications for use

A broad-spectrum anthelmintic for the treatment of cattle and sheep infected with mature and developing immature forms of nematodes of the gastro-intestinal and respiratory tracts.

Cattle

For the treatment of cattle infected with:

Ostertagia spp.

Cooperia spp.
Trichostrongylus spp. Nematodirus spp.
Oesophagostomum spp. Haemonchus spp.
Bunostomum spp. Strongyloides spp.
Trichuris spp. Dictyocaulus viviparus
The product is usually effective against inhibited larvae of Ostertagia spp. and against Moniezia spp. of tapeworm.

Sheep

For the treatment of sheep infected with benzimidazole susceptible:

Ostertagia spp. Haemonchus spp.
Trichostrongylus spp. Nematodirus spp.
Oesophagostomum spp. Cooperia spp.
Chabertia spp. Bunostomum spp.
Strongyloides spp. Dictyocaulus filaria
The product is usually effective against Moniezia spp. of tapeworm and may have useful but variable efficacy against Trichuris spp.

Horses

For the treatment and control of adult and immature roundworms of the gastro-intestinal tract in horses and other equines.

The product effectively treats and controls the following roundworm infections:

Large strongyles (adults and migrating larval stages of Strongylus vulgaris; adults and tissue larval stages of S. edentatus).

Benzimidazole-susceptible adult and immature small strongyles (Cyathostomes).

The product is also effective for the treatment and control of encysted mucosal 3rd and 4th stage small strongyle larvae and is also effective against encysted inhibited 3rd stage small strongyle larvae in the mucosa.

Adult and immature Oxyuris spp., Strongyloides spp. and Parascaris equorum.

Fenbendazole also has an ovicidal effect on nematode eggs.

Contraindications

Do not use in horses and other equines intended for human consumption.

Fenbendazole as a medicated liquid feed should not be used in the treatment of clinical infestations in cattle and sheep.

Special warnings for each target species

When administered by divided dosage in the form of liquid feed, the product may not be effective against Strongyloides and Trichuris spp. in cattle and Strongyloides, Dictyocaulus and Bunostomum spp. in sheep.

Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:

  • Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
  • Under dosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
  • Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.

    Resistance to benzimidazoles (which include fenbendazole) has been reported in Teladorsagia, Haemonchus, Cooperia and Trichostrongylus species in small ruminants in a number of countries, including the EU. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

    Resistance to fenbendazole has been reported in cyathostomes in horses. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.

    Special precautions for use

    When incorporating this product into liquid feed, after thoroughly shaking the suspension, measure the required volume of the suspension and add it to approximately 10 % of the liquid feed. Thoroughly mix this material and then add the remaining liquid feed and once again mix to produce a homogenous dispersion.

    Mix the medicated feed thoroughly prior to administration for example by rolling the drum or barrel.

    Assess body weight as accurately as possible before calculating the dosage.

    Intensive use or misuse of anthelmintic can give rise to resistance. To reduce this risk, dosing programmes should be discussed with your veterinary surgeon.

    Operator warnings

    Direct contact with the skin should be kept to a minimum. Wear suitable protective clothing including impermeable rubber gloves.

    Wash hands after use.

    Adverse reactions

    None.

    Use during pregnancy or lactation

    The product can be administered to pregnant animals. Pregnant mares and young foals may also be safely treated with fenbendazole at the therapeutic dosage levels.

    Interactions

    None known.

    Amounts to be administered and administration route

    Shake container before use. For oral administration only.

    No dietary control is required before or after treatment.

    To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.

    Cattle and Horses: Administer orally 1 ml of the product per 13 kg body weight. (= 7.5 mg fenbendazole/kg body weight)

    Practical dosage recommendations:
    65 kg 5 ml
    135 kg 10 ml
    200 kg 15 ml
    265 kg 20 ml
    335 kg 25 ml
    400 kg 30 ml
    Above 400 kg, an extra 3.75 ml are required for each additional 50 kg body weight.

    Sheep: Administer orally 0.5 ml per 10 kg body weight (= 5 mg fenbendazole/kg body weight)

    Practical dosage recommendations:
    Up to 10 kg 0.5 ml
    11 to 20 kg 1.0 ml
    21 to 30 kg 1.5 ml
    31 to 40 kg 2.0 ml
    41 to 50 kg 2.5 ml
    51 to 60 kg 3.0 ml
    61 to 70 kg 3.5 ml
    71 to 80 kg 4.0 ml
    Above 80 kg, an extra 0.5 ml is required for each additional 10 kg body weight.

    The product is best administered to cattle with the Panacur 20 ml Automatic Drencher and to sheep with the 5ml Sheep Drencher, but other standard dosing guns or drenching equipment may also be used.

    For administration to horses, thoroughly mix the product with grain or concentrate feed and give the full dosage as one administration.

    Treatment should be repeated when natural re-infection of animals with parasitic worms occurs.

    Horses: Recommended dosage programme.

    All horses should be routinely wormed with the single dose regimen every 6-8 weeks.

    Treatment of encysted inhibited and encysted mucosal dwelling larvae should be performed in the autumn (ideally late October/November) and again in the Spring (ideally in February). However, for horses who fail to maintain condition or bought-in horses with unknown worming history, the treatment can be given at any time of the year.

    Five day course

    For the treatment and control of migrating and issue larval stages of large strongyles, encysted mucosal 3rd and 4th stage small strongyle larvae and encysted inhibited 3rd stage small strongyle larvae in the mucosa administer 5 ml of the product per 64 kg body weight daily for 5 days (= 7.5 mg fenbendazole/kg body weight daily for 5 days).

    Single dose treatment

    For the treatment and control of encysted mucosal stages of small strongyles administer 3 ml of the product per 10 kg body weight (= 30 mg fenbendazole / kg body weight).

    For the treatment and control of migrating and tissue stages of large strongyles administer 6 ml of the product per 10 kg body weight (= 60 mg fenbendazole / kg body weight).

    For the treatment of diarrhoea cause by Strongyloides westeri in two to three week old sucking foals administer 5 ml of the product per 10kg body weight (= 50mg fenbendazole / kg body weight).

    Do not mix with other products.

    Overdose

    Benzimidazoles have a high margin of safety. No specific overdose symptoms are known. No specific actions required.

    Withdrawal periods

    Cattle – Meat: 12 Days

    Milk: 5 Days

    Sheep - Meat: 15 Days

    Milk: 7 Days

    Not to be used in horses intended for human consumption.

    Treated horses may never be slaughtered for human consumption.

    The horse must have been declared as not intended for human consumption under national horse passport legislation.

    Pharmacological particulars

    Pharmacodynamic properties

    ATC Vet Code: QP52AC13

    Fenbendazole is an anthelmintic belonging to the benzimidazole carbamates group. It acts by interfering with the energy metabolism of the nematode. The anthelmintic efficacy is based on inhibition of the polymerisation of tubulin to microtubuli. The anthelmintic affects both adult and immature stages of gastro-intestinal and respiratory nematodes.

    Pharmacokinetic properties

    Fenbendazole is only partly absorbed after oral administration and is then metabolised in the liver.

    The half life of fenbendazole in serum after oral application of the recommended dose in cattle is 10-18 hours and in sheep 21-33 hours. Fenbendazole and its metabolites are distributed throughout the body and high concentrations can be found in the liver. The elimination of fenbendazole and its metabolites occurs primarily via the faeces (>90%) and to a small extent in the urine and milk. Fenbendazole is metabolised to its sulfoxide then to sulfone and amines.

    Pharmaceutical particulars

    Excipients

    Sodium methyl hydroxybenzoate

    Sodium propyl hydroxybenzoate

    Benzyl alcohol

    Silica colloidal

    Carmellose sodium

    Povidone

    Sodium citrate dihydrate

    Citric Acid

    Water purified

    Major incompatibilities

    None.

    Shelf life

    Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.

    Shelf-life after first opening of the immediate packaging:

    Liquid feed containing the product will remain stable for up to 3 months.

    Special precautions for storage

    Do not store above 25°C. Protect from frost. Do not freeze.

    Shake container before use. Keep container in its outer carton.

    Immediate packaging

    1, 2, 5 and 10 litre multidose containers. Container: opaque white high density polyethylene. Closure: Tamper proof aluminium foil seal with polyethylene screw cap.

    Disposal

    Any unused product or waste material should be disposed of in accordance with national requirements. DANGEROUS to aquatic life. Do not contaminate ponds, waterways or ditches with the product or used container.

    Marketing Authorisation Number

    UK: Vm 01708/4435

    Significant changes

    Date of the first authorisation or date of renewal

    24 January 1994

    Date of revision of the text

    November 2015.

    Any other information

    For animal treatment only. Keep out of the sight and reach of children.

    Legal category

    Legal category:POM-VPS

    GTIN

    GTIN description:Panacur 10% SU 1x1l:

    GTIN:08713184036032,

    GTIN description:Panacur 10% SU 1x2l:

    GTIN:08713184036049,

    GTIN description:Panacur 10% SU 1x5l:

    GTIN:08713184036056,

    GTIN description:Panacur 10% SU 1x10l:

    GTIN:08713184036063

    PAN1L 5L: Data Sheet

    Delivery

    Shipping charges mainland UK zone1

    ValueWeightDelivery Charge
    Over £49.00Any WeightFREE
    Under £49.00No weight limit£4.50
    Under £49.00Under 250g£2.99

    Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

    NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

    Estimated "Usually shipped in" information is shown against most products

    Overseas orders

    Postage outside of the UK is from £4.50

    Prescription Items

    Prescription items will be sent on receipt of a valid signed and dated prescription.

    Pick up

    We offer a pickup service for orders placed over the phone.

    Please ring us on 01833 641112 for more information.

    Refrigerated Items

    Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

    Returns

    We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.

    *Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

    Frequently Asked Questions

    Can I mix panacur liquid in my horses feed as hes a so and so to take it

    Yes this is to be added to the feed. 

    Is this panacur liquid to be given to each horse over 5 days I.e. the same as panacur guard

    Yes the Panacur Liquid can be given daily for 5 days to treat the encysted small redworm. 

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