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Oxytocin S 25ml

Item Number: OXYTOCIN

Oxytocin S 25ml
  • 25ml

    Estimated dispatch on Wednesday

    £ 16.95

Total: £0.00

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You are ordering a PRESCRIPTION ONLY medicine. Please do NOT continue unless you are sending us a valid prescription.

 

 


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Description

Injections of Oxytocin-S will initiate strong, regular and purposeful contractions of the uterine muscle especially in the later stages of pregnancy and post-partum. Oxytocin-S evokes the `let down' of milk although it has no action on the smooth muscles of the gut or urinary bladder, nor is it effective in the treatment of diabetes insipidus.


Data Sheets

Oxytocin-S, 10 iu/ml, solution for injection Species:Cats, Cattle, Dogs, Goats, Horses and other equidae, Pigs, Sheep

Therapeutic indication:Pharmaceuticals: Hormones and therapeutically related products: Pituitary hormones

Active ingredient:Oxytocin

Product:Oxytocin-S, 10 iu/ml, solution for injection

Product index:Oxytocin-S

Cattle - milk:Zero hours

Cattle - meat:Zero days

Sheep - meat:Zero days

Pig - meat:Zero days

Withdrawal notes:Horse and Goat Zero days

Qualitative and quantitative composition

Each ml contains:

Active substance:

Oxytocin 10 iu

(equivalent to 0.018 mg oxytocin)

Excipients:

Chlorbutanol 5 mg

(Added as Chlorbutanol hemihydrate 5.254 mg as a preservative)

For the full list of excipients, see section “Pharmaceutical particulars”.

Pharmaceutical form

Solution for Injection

Clear aqueous solution

Clinical particulars

Target Species

Cattle, horses, pigs, sheep, goats, cats and dogs

Indications for use

Injections with this product will initiate strong, regular and purposeful contractions of the uterine muscle especially in the later stages of pregnancy and post-partum. It also evokes the 'let-down' of milk although it has no action on the smooth muscles of the gut or urinary bladder, nor is it effective in the treatment of diabetes insipidus. The absence of vasopressor and antidiuretic effects make it particularly suitable for obstetric use (stimulation of parturition, promotion of uterine involution and control of post-partum haemorrhage) and the treatment of agalactia.

The product is indicated for:

- stimulation of uterine contraction to facilitate parturition in the presence of a fully dilated cervix

- to promote involution of the post-parturient uterus and thus aid the passage of

retained placenta

- to aid in control of post-partum haemorrhage

- promotion of milk 'let-down' in cases of agalactia and to facilitate ‘stripping

out’ of infected quarters in the treatment of mastitis in cows.

Contraindications

1. When the product is used as an aid to parturition, cervical dilation must be confirmed prior to administration to prevent the risk of foetal death and possible uterine rupture.

2. The product is contraindicated in any form of obstructive dystocia.

3. Excessive doses of the product may delay parturition by producing incoordinated uterine contractions which interfere with the progress of the foetus especially in multiple pregnancies.

4. The effects of daily dosages of 100 iu or more (to facilitate ‘stripping out’ of infected quarters in the treatment of mastitis in cows) on the oestrous cycle have not been fully investigated and the cycle length may be altered.

5. Adrenaline at physiological levels markedly reduces the effect of oxytocin on the uterus or mammary gland. For this reason, the animal should not be frightened when complete oxytocin effect is desired to cause either milk 'letdown' or uterine contractions.

Special warnings for each target species

None

Special precautions for use

Use aseptic precautions.

Operator warnings

Pregnant or lactating women should avoid handling the product as it could cause smooth muscle (e.g. uterine) contraction.

When administering the product, care should be taken to avoid accidental self-injection.

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse Reactions

None known

Use during pregnancy or lactation

Used to promote parturition and milk let-down. Not to be used in late pregnancy unless the intention is to promote parturition.

Interactions

Stimulation of beta-adrenergic receptors may reduce the effect of oxytocin on the uterus or mammary gland.

Amounts to be administered and administration route

The product should normally be given by deep intramuscular injection.

Species

Dosage mls
Queen 2-5 iu 0.2-0.5 ml
Bitch 2-10 iu 0.2-1.0 ml
Ewe,goat,sow 2-10 iu 0.2-1.0 ml
Mare 10-40 iu 1.0-4.0 ml
Cow Indications other than mastitis as listed in section 'Indications'. For mastitis treatment see below 10-40 iu 1.0-4.0 ml
Adjunct to mastitis treatment in cows:

A single dose of up to 80 iu (8 ml) prior to stripping out before first mastitis treatment followed by repeated doses of 20 iu (2 ml) prior to each stripping out 2 or 3 times daily while mastitis treatment continues.

Where the intravenous route is used, these doses should be reduced to one-quarter of the intramuscular dose and the injection given slowly at a dilution of 1 in 10 Water for Injections Ph.Eur. Where speed of onset is not a priority, the product may be given by the subcutaneous route.

A low initial dosage is recommended by any route as repeat administration is permissible.

Large doses may be employed in post-parturient animals.

Overdose

Excessive doses might cause uncoordinated uterine contractions (also refer to contraindications).

Withdrawal periods

Cattle, sheep, pigs, horses and goats: Meat – Zero days

Cattle, sheep and goats: Milk – Zero hours

Pharmacological particulars

ATC Vet Code: QH01BB02

Pharmacotherapeutic group

Pituitary and hypothalamic hormones and analogues, Posterior pituitary lobe hormones, Oxytocin and analogues

Pharmacodynamic properties

The active ingredient is synthetic oxytocin which is a nature-identical nanopeptide. Oxytocin is a hormone which enhances the contractility of the uterus muscle especially during parturition and post partum, it also evokes let-down of milk. It has no vasopressor or antidiuretic activity.

Pharmacokinetic particulars

Following injection, oxytocin has a rapid onset of activity as physiological effects are usually detected within minutes following administration. Oxytocin is cleared very fast, as its mean half life of distribution is around 2 minutes while its half life of elimination is around 12 minutes.

Pharmaceutical particulars

Excipients

Chlorbutanol hemihydrate

Sodium chloride

Acetic acid or sodium hydroxide used for pH adjustment

Water for injections

Major incompatibilities

In the absence of compatibility studies, this veterinary medicinal product must not be mixed with any other veterinary medicinal products

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 3 years

Shelf life after first opening the immediate packaging: 28 days.

Special precautions for storage

Store in a refrigerator (between +2oC and +8oC). Protect from light.

Immediate packaging

Colourless glass (Type II) vial, closed with bromobutyl rubber stoppers and sealed with aluminium caps.

Pack size: 25 ml.

Disposal

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local

requirements.

Marketing Authorisation Holder (if different from distributor)

Marketing Authorisation Number

UK: Vm01708/4314

Significant changes

Date of the first authorisation or date of renewal

29 July 1994.

Date of revision of the text

November 2019.

Any other information

For animal treatment only. Keep out of the sight and reach of children.

Legal category

Legal category:POM-V

GTIN

GTIN description:Oxytocin-S 1x25ml:

GTIN:08713184006059

Delivery

Shipping charges mainland UK zone1

ValueWeightDelivery Charge
Over £49.00Any WeightFREE
Under £49.00No weight limit£4.50
Under £49.00Under 250g£2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

Returns

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

Frequently Asked Questions

Can this be given to a bitch in labour

This is a prescription only medicine, please speak to your veterinary surgeon. 

Hi do we need prescription

Yes this is a prescription only medicine 

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