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EasOtic 10ml

Item Number: EASOTIC

EasOtic 10ml
  • 10ml

    Estimated dispatch on Friday

    £ 17.25

    Web code: Q10092

Total: £0.00

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You are ordering a PRESCRIPTION ONLY medicine. Please do NOT continue unless you are sending us a valid prescription.

 

 


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Description

EasOtic - eliminates guesswork and improves compliance while delivering all that is needed for safe, effective treatment of otitis externa in dogs.


Data Sheets

Easotic Species:Dogs

Therapeutic indication:Pharmaceuticals: Antimicrobials: Topical preparations: Ear/eye/nose

Active ingredient:Hydrocortisone Aceponate, Gentamicin Sulfate, Miconazole Nitrate

Product:Easotic

Product index:Easotic

Presentation

Ear drops suspension for dogs containing:

Hydrocortisone aceponate 1.11mg/mL

Miconazole as nitrate 15.1mg/mL

Gentamicin as sulfate 1505IU/mL

Uses

Treatment of acute otitis externa and acute exacerbation of recurrent otitis externa associated with bacteria susceptible to gentamicin and fungi susceptible to miconazole in particular Malassezia pachydermatis.

Dosage and administration

Auricular use. One mL contains 1.11mg hydrocortisone aceponate, 15.1mg miconazole (as nitrate) and 1505 IU gentamicin (as sulfate).

It is recommended that the external ear canal should be cleaned and dried before treatment and excess hair around the treatment area be cut.

Shake the bottle thoroughly before first administration and prime the pump.

The recommended dosage is 1mL of the veterinary medicinal product per ear once a day for five consecutive days.

Introduce the atraumatic canula in the ear canal. Administer one dose (1mL) of the product in each affected ear. This dose is adequately delivered by one pump activation. The airless pump allows the product to be administered whatever the position of the bottle is.

After application, the base of the ear may be massaged briefly and gently to allow the preparation to penetrate to the lower part of the of the ear canal. The product as presented allows treating a dog suffering from bilateral otitis. The veterinary medicinal product should be used at room temperature (i.e. do not instil cold product).

Contra-indications, warnings, etc

Contraindications

Do not use in cases of hypersensitivity to the active substances or to any of the excipients, to corticosteroids, to other azole antifungal agents and to other aminoglycosides.

Do not use if the eardrum is perforated.

Do not use concurrently with substances known to cause ototoxicity.

Do not use in dogs with generalised demodecosis.

Special warnings

Bacterial and fungal otitis is often secondary in nature and appropriate diagnosis should be used to determine the primary factors involved.

Special precautions for use

Special precautions for use in animals

If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate therapy instituted. Use of the veterinary medicinal product should be based on identification of infecting organisms and susceptibility testing and take into account official and local antimicrobial policies.

Use of the veterinary medicinal product deviating from the instructions given in the SPC may increase the prevalence of bacteria and fungi resistant to gentamicin and miconazole respectively and may decrease the effectiveness of treatment with aminoglycosides and azole antifungal agents, due to the potential for cross-resistance.

In case of parasitic otitis, an appropriate acaricidal treatment should be implemented. Before the veterinary medicinal product is applied, the external auditory canal must be examined thoroughly to ensure that the ear drum is not perforated in order to avoid the risk of transmission of the infection to the middle ear and to prevent damage to the cochlear and vestibular apparatus.

Gentamicin is known to be associated with ototoxicity when administered by the systemic route at higher doses.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

In case of accidental skin contact, it is recommended to wash thoroughly with water.

Avoid contact with eyes. In case of accidental contact, rinse with abundant quantities of water. In case of eye irritation, seek medical advice. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions (frequency and seriousness)

Mild to moderate redness of the ear was common (2.4% of treated dogs). Papules were observed uncommonly (less than 1% of treated dogs). In all cases, treatment with the veterinary medicinal product was not discontinued and all dogs recovered without any specific therapy. In very rare cases, the use of the veterinary medicinal product has been associated with hearing impairment (partial hearing loss or deafness), primarily in geriatric dogs. Based on post-marketing safety experience, hearing improvement was observed in most dogs with deafness/loss of hearing and complete recovery was confirmed in 70% of cases with an adequate follow-up. Among dogs with full recovery, improvement has been rapidly seen. Recovery has been observed as early as one week after onset of signs, the majority of dogs recovering within one month; in a minority of reports, the deafness lasted for up to two months.

If deafness or partial hearing loss occurs, treatment should be stopped. In very rare cases, type-I hypersensitivity reactions (facial swelling, allergic pruritus) have been observed. If this occurs, treatment should be stopped.

The frequency of adverse reactions is defined using the following convention:

- very common (more than 1 in 10 animals treated displaying adverse reaction(s))

- common (more than 1 but less than 10 animals in 100 animals treated)

- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)

- rare (more than 1 but less than 10 animals in 10,000 animals treated)

- very rare (less than 1 animal in 10,000 animals treated, including isolated reports.

Use during pregnancy, lactation or lay

The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Systemic absorption of hydrocortisone aceponate, gentamicin sulphate and miconazole nitrate being negligible, it is unlikely for teratogenic, foetotoxic or maternotoxic effects to occur at the recommended dosage in dogs. Use only accordingly to the benefit-risk assessment by the responsible veterinarian.

Interaction with other medicinal products and other forms of interaction

Compatibility with ear cleaners has not been demonstrated.

Pharmaceutical precautions

Keep out of the sight and reach of children. This medicinal veterinary product does not require any special storage conditions. Do not use after the expiry date stated on the label. Once open use within 10 days.

Legal category

Legal category:POM-V

Packaging quantities

Box containing 1 multidose container (the content of 10mL is equivalent to 10 doses).

Further information

Nil

Marketing Authorisation Number

EU/2/08/085/001

Delivery

Shipping charges mainland UK zone1

ValueWeightDelivery Charge
Over £49.00Any WeightFREE
Under £49.00No weight limit£4.50
Under £49.00Under 250g£2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

Returns

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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