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Crystapen 5 Mega Units 3g solution for injection for horses

Item Number: CRYSTAPEN

Crystapen 5 Mega Units 3g solution for injection for horses

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Description

Crystapen 5 Mega Units 3 g. Powder for solution for injection.

Presentation

1 vial of white crystalline powder for solution for injection contains 3 g of Benzylpenicillin (as Benzylpenicillin Sodium 95.7% w/w) equivalent to 5 mega-units of benzylpenicillin.

Uses

For use in horses.

For the treatment and control of acute and severe systemic infections caused by or associated with organisms sensitive to penicillin including: Arcanobacterium pyogenes, Erysipelothrix rhusiopathiae, Klebsiella pneumoniae, Listeria spp., Mannheimia haemolytica, Pasteurella multocida, Proteus spp., Pseudomonas aeruginosa, Rhodococcus equi, Staphylococcus aureus, Streptococcus zooepidemicus, some Salmonella spp.

The product may be used in pregnant and lactating animals.

Dosage and administration

The recommended dosage is 10 mg/kg twice daily for 1 day by intravenous injection. The usual aseptic precautions should be followed. The following guide is given to enable practical dose volumes to be administered.

Animal

Weight

(kg)

Reconstitution

water volume

(ml) per vial

Volume of

reconstituted

material for

administration (ml)

Dosage

(mg/kg)

50

18.0

3.0

10.0

75

10.0

2.5

10.0

100

10.0

3.3

10.0

150

10.0

5.0

10.0

200

6.0

4.0

10.0

500

6.0

10.0

10.0

Note: Each vial contains 3g of benzylpenicillin

To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.

Contra-indications, warnings, etc

Do not use in known cases of hypersensitivity to penicillins. Do not use in small mammals (eg. gerbils, rabbits).

Penicillins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious. Do not use in animals known to be sensitive to penicillin.

Adverse reactions include hypersensitivity in susceptible animals and diarrhoea.

The usual aseptic precautions should be followed when administering the product. Not for intrathecal administration.

Use of the product should be based on susceptibility testing of bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria.

Operator warnings

Care should be taken to avoid accidental self-injection.

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitive to penicillins, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure such as a skin-rash you should seek medical advice and show the Doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

Wash hands thoroughly after use.

Withdrawal periods

Not to be used in horses intended for human consumption.

Treated horses may never be slaughtered for human consumption.

The horse must have been declared as not intended for human consumption under national horse passport legislation.

For animal treatment only. Keep out of the reach and sight of children.

Pharmaceutical precautions

Do not store above 25ºC.

Reconstituted solutions may be stored for a maximum of 24 hours at 2-8ºC.

Disposal advice

Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Legal category

POM-V

Packaging Quantities

Glass vial with (type III) grey rubber bromobutyl bung with aluminium overseal containing powder for reconstitution.


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