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Canixin DHPPi/L Suspension for Injection for Dogs (50 dose)

Item Number: CANIXDHPP

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Canixin DHPPi/L Suspension for Injection for Dogs (50 dose).

Target species


Indications for use

For active immunisation of dogs from 8 weeks of age to:

-prevent mortality and clinical signs of canine distemper and infectious canine hepatitis caused by canine adenovirus type 1;

-prevent mortality and clinical signs and reduce excretion caused by canine parvovirus in a challenge study performed with a CPV2b strain;

-reduce respiratory clinical signs caused by canine parainfluenza virus;

-prevent mortality and reduce infection, clinical signs, kidney colonisation, renal lesions and urine shedding of L. canicola and L. icterohaemorrhagiae;

The onset of immunity has been demonstrated from 3 weeks after the primary vaccination for CDV and CPV, 4 weeks for CAV-1 and CPIV, 5 weeks for L. canicola and 2 weeks for L. icterohaemorrhagiae.

The duration of immunity lasts for one year after the primary vaccination for all components. For CAV-2 and CPV components, the duration of immunity was demonstrated by serological data.



Special warnings for each target species

After vaccination, the live viral vaccinal strains (CAV-2, CPV) can be spread to unvaccinated animals without any pathological effect for these in-contact animals.

The presence of maternally derived antibodies (puppies from vaccinated females) can interfere with the vaccination. Therefore the vaccination scheme should be adapted accordingly (see section 4.9).

Special precautions for use

i. Special precautions for use in animals

Vaccinate only healthy animals

ii.Special precautions to be taken by the person administering the veterinary medicinal product to animals

-In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

iii.Other precautions


Adverse reactions

After the administration of one dose of DHPPi/L vaccine most of the animals may exhibit a mild and transient swelling ( = 4 cm) or slight diffuse local oedema. This reaction resolves spontaneously within 1 to 12 days. In very rare cases pain and pruritus may occur. However these small transient injection site reactions resolve without treatment.

In very rare cases, the vaccination can induce a transient diarrhoea, hyperthermia or weakness. Hypersensibility reactions can be sometimes observed. In case of allergic or anaphylactic reaction, appropriate symptomatic treatment should be administered.

Use during pregnancy, lactation or lay

Do not use during pregnancy and lactation.


No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.

Amounts to be administered and administration route

After reconstitution of the lyophilisate with the solvent, shake gently and administer immediately one dose of 1 ml subcutaneously according to the following vaccination schedule:

Primary vaccination course :

- first injection from 8 weeks of age

- second injection 3 or 4 weeks later.

Annual re-vaccination:

One booster injection of a single dose should be given 1 year after the second injection and annually thereafter.

Maternally derived antibodies can negatively influence the immune response to vaccination. In these cases, a third injection is recommended from 15 weeks of age.


The 10 doses administration of the vaccine in one single injection site showed no other reactions than those mentioned in the section “Adverse reactions” except for the duration of the local reactions (up to 26 days).

Withdrawal periods

Not applicable

Pharmacological particulars

Immunological properties

-ATCvet code QI07AI02

-To stimulate active immunity against canine distemper virus, canine adenovirus, canine parvovirus, canine parainfluenza virus and L. interrogans serogroup canicola and L. interrogans serogroup icterohaemorrhagiae

Pharmaceutical particulars


Lyophilisate :


Potassium hydroxide

Lactose monohydrate

Glutamic acid

Potassium dihydrogen phosphate

Dipotassium phosphate

Water for injections

Sodium chloride

Disodium phosphate anhydrous

Suspension :

Sodium hydroxide


Dipotassium phosphate

Potassium dihydrogen phosphate


Water for injections

Major incompatibilities

Do no mix the vaccine with any other veterinary medicinal product.

Shelf life

Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.

Shelf-life after reconstitution according to directions: use immediately after reconstitution.

Special precautions for storage

Store and transport refrigerated (2°C – 8°C)

Protect from light

Do not freeze

Immediate packaging

Type I glass Vial

Elastomer stopper

Aluminium Cap


Any unused product or waste material should be disposed of in accordance with the local requirements.

Data Sheets


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