Previcox Chewable Tablets

Previcox Chewable Tablets

Average Rating 5/5 (69 reviews)    
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Item Number: PREVICOX 
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227mg (pack of 60) £46.19 Usually despatched within 24 hours
57mg Single Tablet £0.48 Usually despatched within 24 hours
227mg Single Tablet £0.77 Usually despatched within 24 hours
57mg (pack of 60) £28.39 Usually despatched within 24 hours

Quantity

NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.
X

You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post

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Description

Presentation

Tan-brown, round, convex, engraved, scored chewable tablets, each containing 57mg or 227 mg firocoxib.

Uses

Firocoxib is a non-steroidal anti-inflammatory drug (NSAID) belonging to the Coxib group, which acts by selective inhibition of cyclooxygenase-2 (COX-2) – mediated prostaglandin synthesis. PREVICOX tablets are for the relief of pain and inflammation associated with osteoarthritis in dogs and for the relief of post-operative pain and inflammation associated with soft-tissue and orthopaedic surgery in dogs.

Dosage and administration

Osteoarthritis:

The recommended oral dose is 5 mg per kg bodyweight once daily, as shown in the table below. Tablets can be administered with or without food. Duration of treatment will be dependent on the response observed. As field studies were limited to 90 days, this should be borne in mind when considering longer-term treatment, with regular monitoring carried out by the veterinarian.

Relief of post-operative pain:

The recommended oral dose is 5 mg per kg bodyweight once daily, as shown in the table below, for up to 3 days as needed, starting approximately 2 hours prior to surgery.

Following orthopaedic surgery and depending on the response observed, treatment using the same daily dosing schedule may be continued after the first 3 days, upon judgement of the attending veterinarian.

Body weight (kg)

Number of chewable tablets

mg/kg range

57mg

227mg

3 - 5.5

0.5

5.2 - 9.5

5.6 - 10

1

5.7 - 10.2

10.1 - 15

1.5

5.7 - 8.5

15.1 - 22

0.5

5.2 - 7.5

22.1 - 45

1

5.0 - 10.3

45.1 - 68

1.5

5.0 - 7.5

68.1 - 90

2

5.0 - 6.7

Contra-indications, warnings, etc

For animal treatment only. Do not exceed the recommended dose. Do not use in pregnant or lactating bitches.

Do not use in animals less than 10 weeks of age or less than 3 kg body weight. Do not use in animals suffering from gastrointestinal bleeding, blood dyscrasia or haemorrhagic disorders. Where there is a risk of gastrointestinal bleeding, or if the animal previously displayed intolerance to NSAIDs, use this product under strict veterinary monitoring.

Vomiting and diarrhoea have occasionally been reported. These reactions are generally of a transitory nature and are reversible when the treatment is stopped. Rarely, nervous system disorders have been reported in treated dogs.

Do not use concomitantly with corticosteroids or other NSAIDs. Use in very young animals, or animals with suspected or confirmed impairment of renal, cardiac or hepatic function may involve additional risk. If such use cannot be avoided, those dogs require careful veterinary monitoring.

Avoid use in any dehydrated, hypovolaemic or hypotensive animals, as there is a potential risk of increased renal toxicity. Concurrent administration of potentially nephrotoxic drugs should be avoided.

Renal and/or hepatic disorders have been reported in very rare cases in dogs administered the recommended treatment dose. It is possible that a proportion of such cases had sub-clinical renal or hepatic disease prior to the commencement of therapy. Therefore, appropriate laboratory testing to establish baseline renal or hepatic biochemistry parameters is recommended prior to and periodically during administration.

The treatment should be discontinued and the advice of a veterinarian should be sought if any of these signs are observed: repeated diarrhoea, vomiting, faecal occult blood, sudden weight loss, anorexia, lethargy, degradation of renal or hepatic biochemistry parameters. As with other NSAIDs, serious adverse effects can occur and, in very rare cases, may be fatal.

Laboratory studies in rabbits have shown evidence of maternotoxic and foetotoxic effects at dose rates approximating the recommended treatment dose for the dog. Pre-treatment with other anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before the commencement of treatment with PREVICOX. The treatment-free period, however, should take into account the pharmacokinetic properties of the products used previously.

PREVICOX must not be administered in conjunction with other NSAIDs or glucocorticosteroids. Gastrointestinal tract ulceration may be exacerbated by corticosteroids in animals given non-steroidal anti-inflammatory drugs.

Concomitant treatment with molecules displaying action on renal flow, e.g. diuretics or Angiotensin Converting Enzyme (ACE) inhibitors, should be subject to clinical monitoring. Concurrent administration of potentially nephrotoxic drugs should be avoided, as there might be an increased risk of renal toxicity. As anaesthetic drugs may affect renal perfusion, the use of parenteral fluid therapy during surgery should be considered to decrease potential renal complications when using NSAIDs peri-operatively.

Concurrent use of other active substances that have a high degree of protein binding may compete with firocoxib for binding and thus lead to toxic effects.

In the event of accidental ingestion, seek medical advice immediately and show the package leaflet or label to the physician. Wash hands after use of the product.

Return halved tablets to the blister and keep out of the reach of children.

Disposal advice

Any unused product or waste material should be disposed of in accordance with local requirements.

Pharmaceutical precautions

Do not store above 300C. Store in the original package. Halved tablets may be kept for up to 7 days in the original container.

Legal category

POM-V

Packaging Quantities

PREVICOX tablets are supplied in carton boxes containing blisters (transparent PVC /aluminium foil and paper backing).

The chewable tablets are available in the following pack sizes:

57mg: 1 carton box containing three blisters of 10 tablets

227 mg: 1 carton box containing three blisters of 10 tablets

Further information

Firocoxib is approximately 96% bound to plasma proteins. Following multiple oral administrations, the steady state is reached by the third daily dose.

Firocoxib is metabolised predominantly by dealkylation and glucuronidation in the liver. Elimination is principally in the bile and gastrointestinal tract.

PREVICOX chewable tablets are scored to facilitate accurate dosing and contain caramel and smoke flavours to facilitate administration to dogs.

Mode of action: Firocoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts by selective inhibition of cyclooxygenase-2 (COX-2) – mediated prostaglandin synthesis. COX-2 is the isoform of the enzyme that has been postulated to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever. In in-vitro canine whole blood assays, firocoxib exhibited approximately 380-fold selectivity for COX-2 over COX-1.

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

Estimated " Usually shipped in" information is shown against most products

 

Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

Overseas orders

Postage outside of the UK is from £4.95

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*Free delivery and selected charges on orders over £49.00 mainland UK Parcelforce Zone1 for more information check the delivery info page.
 
 

Reviews

 feefoProduct Reviews


Previcox Chewable Tablets POM 57mg Single Tablet

these work well for my dog's arthritis in conjunction with tramadol


Previcox Chewable Tablets POM 227mg Single Tablet

Allows my other oldie to perambulate. He cannot use metacam.


Previcox Chewable Tablets POM 227mg Single Tablet

Supplied on prescription from my vet who charges double Hyperdrug prices.


Previcox Chewable Tablets POM 57mg Single Tablet

combined with tramadol seem to help my dog cope with arthritis


Previcox Chewable Tablets POM 227mg (pack of 60)

Genuine product, great quality


Previcox Chewable Tablets POM 227mg (pack of 60)

They work and the dog eats them ok


Previcox Chewable Tablets POM 227mg (pack of 60)

Worked fairly well with arthritic dogs


Previcox Chewable Tablets POM 227mg Single Tablet

As Above


Previcox Chewable Tablets POM 227mg Single Tablet

Dog much better on medication


Previcox Chewable Tablets POM 227mg Single Tablet

Keeps my elderly greyhound pain free and mobile


Previcox Chewable Tablets POM 227mg (pack of 60)

Excellent


Previcox Chewable Tablets POM 227mg Single Tablet

As Above


Previcox Chewable Tablets POM 57mg (pack of 60)

given to an elderly c.k.c.spaniel for pain and discomfort she suffers with SM.


Previcox Chewable Tablets POM 57mg Single Tablet

half a tablet twice a day helps considerably hopefully she will be with us for a long time yet


Previcox Chewable Tablets POM 227mg (pack of 60)

Vet prescribed - does what it says on the tin.


Previcox Chewable Tablets POM 227mg (pack of 60)

Excellent


Previcox Chewable Tablets POM 227mg (pack of 60)

Good


Previcox Chewable Tablets POM 227mg (pack of 60)

Good painkillers, easy to administer.


Previcox Chewable Tablets POM 227mg (pack of 60)

Excellent


Previcox Chewable Tablets POM 227mg (pack of 30)

they seem to work to improve his arthritis


Previcox Chewable Tablets POM 227mg (pack of 30)

Excellent


Previcox Chewable Tablets POM 227mg (pack of 30)

As Above


Previcox Chewable Tablets POM 227mg (pack of 60)

As Above


Previcox Chewable Tablets POM 227mg (pack of 30)

My dogs have been on Previcox for 2 years, they are well and happy.


Previcox Chewable Tablets POM 227mg (pack of 30)

My elderly dog has arthritis and Previcox helps him to walk more easily without upsetting his stomach.

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