Ovuplant 2.1mg Implantation Tablets for Horses (Mares) (Pack 5)

Browse other products from the Ovuplant product range

Ovuplant 2.1mg Implantation Tablets for Horses (Mares) (Pack 5)


Be the first to review this item

Item Number: OVUPLANT 
Phone orders quick webcode: 

Unit Price:

£237.59 (Incl. Vat)

Usually despatched within 24 hours

Quantity

NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.
X

You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post



Description

Ovuplant 2.1mg Implantation Tablets for Horses (Mares) (Pack of 5). Target species: Horses (non-pregnant mares).

Indications for use:
In mares: Zootechnical treatment for the induction of ovulation within 48 hours, during oestrus in normally cycling mares (in sexual season), with an ovarian follicle greater than 30 mm diameter.

Special warnings for each target species:
Mares should be implanted with the veterinary medicinal product when a developing ovarian follicle greater than 30 mm in diameter has been detected by rectal palpation and/or ultrasonography. In larger breeds, it may be necessary to wait until the dominant follicle has progressed to 35 mm in diameter before administration of the veterinary medicinal product.

Treated mares should be bred or inseminated within the next 48 hours. The mare should be monitored to ensure that ovulation has occurred and that further breedings are not required. If ovulation does not occur within 48 hours of implantation, continue breeding according to routine management procedures.

It has been noted that follicles were significantly smaller before ovulation for deslorelin treated mares compared with placebo mares. However, treatment had no effect on the percentage of mares pregnant at days 18 or 50.

For all trials that evaluated conception and pregnancy rate, there were no differences between deslorelin-treated and non-treated mares at the end of the study.

Efficacy has not been established for mares in vernal (spring) transition phase.

Special precautions for use in animals:
Do not use if the foil pouch is broken.

Only one implant should be implanted per mare during a given oestrus.

The veterinary medicinal product has not been tested in mares less than three (3) years of age.

Use only in mares fit for reproduction.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Pregnant women should not administer the veterinary medicinal product as GnRH analogues have been shown to be foetotoxic in laboratory animals.

When administering the veterinary medicinal product, take care to avoid accidental self-injection by ensuring that animals are suitably restrained and the application needle is shielded until the moment of implantation.

In the case of accidental self-injection, seek medical assistance immediately, with a view to having the implant removed, as GnRH analogues may have adverse effects on the male and female reproductive systems.

Although skin contact with the veterinary medicinal product is unlikely, should this occur, wash the exposed area immediately with soap and water, as GnRH analogues may be absorbed through the skin.

Adverse reactions:
Localised swelling and mild fibrosis at the site of implantation has been observed in some mares, accompanied by a slight increase in sensitivity to touch and an elevated skin temperature. These effects are transient and usually resolve without treatment within 2 to 5 days.

Some mares implanted with the veterinary medicinal product (deslorelin) may experience an increased dioestrous period following use.

Use during pregnancy and lactation:
Do not use during pregnancy. GnRH analogues have been shown to be foetotoxic in laboratory animals when administered during pregnancy.

Amounts to be administered and administration route:
One implant should be administered by subcutaneous implantation in the lateral neck region midway between the head and shoulder.

Prepare the implantation site by thoroughly cleaning the skin with an appropriate disinfectant. Insert the entire length of the needle subcutaneously and fully depress the syringe plunger. Slowly withdraw the needle while pressing the skin at the insertion site. Examine the syringe and needle to ascertain that the implant has not remained within the syringe or needle. It may be possible to palpate the implant in situ.

The implant is absorbed and does not require removal.

Do not attempt to re-use the implanter.

Overdose:
In safety and tolerance studies, the only systemic adverse effect seen in mares receiving up to 10 implants simultaneously was suppression of ovarian activity.

Withdrawal periods:
Meat and offal: 7 days. Do not use in mares producing milk for human consumption.

Pharmacodynamic properties:
Deslorelin is a synthetic oligopeptide analogue of gonadotropin releasing hormone used to advance ovulation in oestrus mares. The mechanism of action of deslorelin corresponds with that of naturally occurring GnRH, stimulating the release of follicle stimulating hormone and luteinising hormone (LH) from the pituitary gland. The increased circulating concentration of LH promotes ovulation in mares with a developing follicle greater than 30 mm in diameter. The use of an implant formulation which releases deslorelin over a short time period results in a pre-ovulatory peak of LH within a narrow time frame, thereby inducing ovulation within 48 hours in a high proportion of mares. The advancement of ovulation in this way decreases the duration of oestrus and allows closer synchronisation of mating with ovulation.

Pharmacokinetic properties:
No direct measurement of deslorelin release in vivo has been carried out in the target species. Due to the mode of action and rapid metabolism of deslorelin, direct measurement of the substance in plasma is not practicable. To overcome this, indirect markers of deslorelin have been used by assaying blood concentrations of LH and FSH. The observation of increased LH and FSH concentrations in blood at 12–48 hours after implantation provides indirect evidence that release of deslorelin is occurring.

Pharmaceutical particulars:
Shelf life:
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Special precautions for storage
Store in a refrigerator (2°C - 8°C).

Immediate packaging:
The implant is supplied preloaded in a polypropylene syringe with an attached stainless steel needle. Each preloaded implanter is supplied in a sealed foil pouch. 5 of these are packaged in a cardboard carton.

Disposal:
Any unused product or waste materials should be disposed of in accordance with national requirements.

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

Estimated " Usually shipped in" information is shown against most products

 

Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

Overseas orders

Postage outside of the UK is from £4.95

Finding out delivery Charges and options before checkout

  1. Simply add an item to your basket
  2. Click view basket/Cart
  3. Click estimate shipping charges
*Free delivery and selected charges on orders over £49.00 mainland UK Parcelforce Zone1 for more information check the delivery info page.
 
 

Reviews

Click here for the product datasheet