Ivomec Super Injection for Cattle 1000ml.
Indications for use
Ivomec Super Injection for Cattle is indicated for the treatment and control of the following parasites:
Sarcoptes scabiei var. bovis
Ivomec Super Injection for Cattle may also be used as an aid in the control of biting lice (Damalinia bovis) and the mange mite Chorioptes bovis, but complete elimination may not occur.
Ivomec Super Injection for Cattle given at the recommended dosage of 0.2 mg per kg bodyweight controls re-infection with Haemonchus placei, Cooperia spp. andTrichostrongylus axei acquired up to 14 days after treatment; Ostertagia ostertagi and Oesophagostomum radiatum acquired up to 21 days after treatment andDictyocaulus viviparus acquired up to 28 days after treatment.
To obtain optimal benefit from the persistent activity of Ivomec Super Injection for Cattle for grazing animals, it is recommended that calves which are set stocked in the first grazing season should be treated 3, 8 and 13 weeks after the day of turn-out. This can protect the animals from parasitic gastroenteritis and lungworm disease throughout the grazing season, provided they are set-stocked, all the calves included in the programme and that no untreated cattle are added to the pasture. Treated animals should always be monitored according to good husbandry practices.
This product is not to be used intramuscularly or intravenously. Ivomec Super Injection for Cattle is a low-volume product registered for use in cattle. It should not be used in other species as severe adverse reactions, including fatalities in dogs, may occur.
Special warnings for each target species
For use only in beef cattle and non-lactating dairy cattle. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
-Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
-Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to macrocyclic lactones (which includes ivermectin) has been reported in Cooperia spp. in cattle within the EU. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use in animals
This product does not contain any antimicrobial preservative. Swab septum before removing each dose.
Special precautions to be taken by the person administering the product to animals
Do not smoke, drink or eat while handling the product. Wash hands after use. Take care to avoid self injection: the product may cause local irritation and/or pain at the injection site.
Transitory discomfort has been observed in some cattle following subcutaneous administration. A low incidence of soft tissue swelling at the injection site has been observed. These reactions disappeared without treatment.
Use during pregnancy, lactation or lay
Ivomec Super Injection for Cattle can be administered to beef cows at any stage of pregnancy or lactation provided that the milk is not intended for human consumption. The product will not affect the fertility of cows and bulls and can be given to all ages of animals including young calves. Please also refer to section ‘Withdrawal period’.
No interactions have been identified with other products.
Amounts to be administered and administration route
Ivomec Super should be administered only by subcutaneous injection at the recommended dosage level of 1 ml/50 kg bodyweight (based on a dosage level of 200 mcg ivermectin plus 2 mg clorsulon per kg bodyweight) under the loose skin in front of, or behind, the shoulder. Divide doses greater than 10 ml between two injection sites. A sterile 17 gauge ½ inch (15-20 mm) needle is recommended. Replace with a fresh sterile needle after every 10-12 animals or sooner if the needle becomes soiled.
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked. When the temperature of the product is below 5 °C, difficulty in administration may be encountered due to increased viscosity.
Warming the product and injection equipment to about 15 °C will greatly increase the ease with which the product can be injected. Different injection sites should be used for other parenteral products administered concurrently. When using the 200 ml, 500 ml and 1000 ml pack sizes, use only automatic syringe equipment. For the 50 ml pack sizes, use of a multidose syringe is recommended.
The administration of 25 ml Ivomec Super per 50 kg bodyweight (25 x the use level) resulted in an injection site lesion (including tissue necrosis, oedema, fibrosis and inflammation). No other drug-related adverse reactions could be determined.
Cattle (meat and offal) - 66 days.
Animals must not be slaughtered for human consumption during treatment. Do not use in cattle producing milk for human consumption. Do not use in non-lactating dairy cows, including pregnant heifers, within 60 days of calving.
Glycerol Formal, Propylene Glycol.
No major incompatibility has been identified.
Shelf life of the product as packaged for sale: 5 years.
Shelf-life after first opening the immediate packaging: 6 months
Special precautions for storage
Protect from direct sunlight. Following withdrawal of the first dose, use the product within 6 months. Discard unused material.
50 ml, 200 ml, 500 ml and 1000 ml containers.
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used container. Any unused product or waste materials derived from such products should be disposed of in accordance with local requirements.
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