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Zylexis Injection for Horses 2ml x 5

Item Number: ZYLEXIS

Zylexis Injection for Horses 2ml x 5
  • 2ml x 5

    Usually dispatched on Friday if ordered within 0 hours and 35 minutes

    £ 140.25

    Web code: Q11121

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Description

Zylexis Injection for Horses 2ml x 5.

Presentation

Zylexis for Horses is presented as a lyophilisate and solvent for suspension for intramuscular injection.

Each 2 ml dose contains inactivated Parapoxvirus ovis, strain D1701 that generates a minimum of 460 IFN Units *.

*: interferon units as determined in an in vitro stimulation assay in cattle lymphocytes.

Uses

Zylexis for Horses acts by stimulation of non-specific immune mechanisms and is of potential clinical value in the reduction of clinical signs of equine respiratory disease associated with stress/crowding.

In a field study, reduction of clinical signs (defined as the first time-point at which significant differences were evident between groups) was shown on day 5 after administration of the full treatment schedule and lasted less than a week.

Dosage and administration

For horses from 10 months of age.

Aseptically reconstitute the lyophilisate with the solvent provided. Shake well before use. The entire contents of the reconstituted vial should be administered intramuscularly as a single dose irrespective of body weight of the animal.

Dosage regimen

Three injections of a single dose for each animal are recommended.

The first two injections are administered with a 48-hour interval (day 0 and day 2) and the 3rd injection is administered on day 9.

To ensure efficacy of the treatment, it is important that the first dose of the product is administered shortly before or up to the day of crowding or exposure to other stressful conditions. It is important that the complete treatment schedule of 3 doses is administered.

Advice on correct administration

Sterile needles and syringes should be used for administration.

Syringes and needles should not have been sterilised chemically or be above ambient temperature. Do not use chemicals to disinfect or sterilise skin.

Shake well before use.

Aseptic precautions should be observed.

Reconstituted vaccine should be used immediately.

Contra-indications, warnings, etc

In a study in which horses of 4-10 months of age were administered Zylexis for Horses according to the recommended dosage regime, no systemic or local reactions were observed.

Special precautions for use in animals

The product should not be used for treatment of animals with chronic diseases with unclear causality.

No information is available to support the use of the authorised schedule in pregnant mares. One overdose (4 ml) was investigated in pregnant mares in the second half of pregnancy up to a few days before parturition.

No systemic or local reactions or negative effects were observed in these mares.

There is no information concerning safety in stallions.

No information is available on the safety and efficacy of this product when used with any other veterinary medicinal product. A decision to use this product before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

In an overdose (4 ml) safety study carried out in 1 day-old horses, no systemic or local reactions were observed.

Do not mix with any other veterinary medicinal product.

If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

All suspected adverse reactions and any suspected lack of efficacy should be reported to Zoetis UK Ltd technical helpline on 0845 300 8034.

Withdrawal period

Zero days.

User warnings

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Pharmaceutical precautions

Store in a refrigerator (2°C – 8°C).

Protect from light.

Do not freeze.

Use immediately after reconstitution.

Do not use after the expiry date stated on the label.

Keep out of the reach and sight of children.

For animal treatment only.

Legal category

POM-V

Packaging Quantities

Boxes containing 5 glass vials of lyophilisate together with 5 glass vials of the solvent.


Data Sheets

ZYLEXIS: Data Sheet


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