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  • 10 x 50g sachet

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Presentation Trimediazine Plain is a white broad spectrum antibacterial powder for incorporation into animal feeding stuffs. Each sachet contains Trimethoprim PhEur 5% w/w and Sulfadiazine PhEur 25% w/w. Uses Trimediazine Plain is indicated for the treatment of bacterial diseases in horses, including upper and lower respiratory tract infections, alimentary tract infections and infected wounds. Dosage and administration Administer with a small quantity of feed. Each 50 g sachet provides a daily dose for a 500 kg horse. The dose may be administered daily, or divided and administered at 12 hourly intervals, for 5 days. Note It is recommended that other feed be withdrawn until medicated feed has been consumed. Contra-indications, warnings, etc Do not use in horses with severe liver parenchymal damage or kidney damage or known sulphonamide sensitivity or horses with blood dyscrasias. To avoid the possibility of crystalluria, adequate water intake is essential. Do not exceed 7 days continuous treatment. When administered to lactating females, small amounts of trimethoprim and sulfadiazine are present in the maternal milk. Since no studies have been reported on the effects of Trimediazine Plain on the development of new born foals, it would be prudent not to feed very young foals with milk obtained from mares being treated. Withdrawal period Meat: 6 months [UK Only - In accordance with the Horse Passport legislation (Commission Decision 2000/68/EC as implemented in national legislation) a 6 month withdrawal period applies to the use of this product]. Operator warnings Avoid direct contact with skin and eyes. If contact occurs, wash affected area with copious amounts of water. Seek medical advice if irritation persists. Gloves should be worn whilst handling this product. Wash hands and exposed skin after use. Avoid inhaling dust from the product. The use of a mask is recommended if the product is handled regularly. Handle only in a well ventilated area. Pharmaceutical precautions Do not store above 25°C. Store in a dry place. Add to feed immediately before administration. After incorporation into feed, any material not used immediately should be discarded Any unused product or waste material should be disposed of in accordance with current practice for pharmaceutical waste under national waste disposal regulations. Legal category POM-V (previously POM). Packaging Quantities 10×50 g sachets. Further information This formulation contains no flavouring. Sulfadiazine is a bacteriostatic antibiotic belonging to the sulphonamide group which acts by interference with the synthesis of nucleic acids. Trimethoprim is a reductase inhibitor which also interferes with the synthesis of nucleic acids. Sulfadiazine and trimethoprim act on the same metabolic pathway, resulting in potentiation of antibacterial activity. Marketing authorisation number VM 08007/4036.

Data Sheets

TRIMEDIAZT10X50G: Data Sheet

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