Horses (mares), cattle (cows), pigs (sows), sheep (ewes), goats (nanny), dogs (bitches) and cats (queen)
Indications for use, specifying the target species
In the mare, cow, sow, ewe, nanny, bitch and queen the product is indicated for:
· Obstetric use (stimulation of uterine contraction to facilitate parturition in the presence of a fully dilated cervix, promotion of involution of the post-partum uterus, aid in the control of post-partum haemorrhage).
· Promotion of milk let-down in cases of agalactia.
Contraindications
Do not use in cases of obstructive dystocia and/or in cases of non-dilatation of the uterine cervix.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Special warnings for each target species
Adrenaline at physiological levels markedly reduces the effect of Oxytocin on the uterus or mammary gland. For this reason the animal should not be frightened when complete Oxytocin effect is desired to cause either milk "let-down" or uterine contractions.
Special precautions for use in animals
When the veterinary medicinal product is used as an aid in parturition cervical dilation must be confirmed prior to administration to prevent risk of foetal death and possible uterine rupture.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Pregnant or lactating women should avoid handling the product as it could cause smooth muscle (e.g. uterine) contraction.
When administering the product, care should be taken to avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Adverse reactions (frequency and seriousness)
None.
Use during pregnancy, lactation or lay
The product is indicated for use, as appropriate, during parturition and lactation. Do not use during pregnancy except at the time of parturition.
Interaction with other medicinal products and other forms of interaction
This veterinary medicinal product maybe used concurrently with antibiotics in the treatment of endometritis.
Stimulation of ß-adrenergic receptors may reduce oxytocin's effects on the uterus and mammary gland.
If sympathomimetic agents or other vasoconstrictors are used concurrently with oxytocin, post-partum hypertension may result.
Amounts to be administered and administration route
Administered by subcutaneous or intramuscular injection.
Mare & Cow 4 – 6 ml
Sow 1 – 3 ml
Ewe & Nanny 1 – 2 ml
Bitch & Queen 0.25 – 1 ml
For treatment of agalactia the stated higher dosage level should be used.
The product may be administered by slow intravenous injection at dose rates one third of the above.
Enhanced dose rates will not result in proportionally increased pharmacological effects.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Excessive doses of the veterinary medicinal product may delay parturition by producing uncoordinated uterine contractions which interfere with the progress of the foetus especially in multiple pregnancies.
Treatment of overdose is palliative and there are no specific antidotes.
Withdrawal period(s)
Meat and offal: zero days.
Milk: zero hours.
Pharmacological particulars
Pharmacotherapeutic group: Systemic hormonal preparations; Posterior pituitary lobe hormones; Oxytocin.
ATCvet code: QH01BB02
Pharmacodynamic properties
Oxytocin is a hormone of the posterior lobe of the hypophysis. It influences the rhythmic contraction of the oxytocin sensitive smooth muscle apparatus. Of special significance is the increase of strength and frequency of the uterine contractions at the beginning of labour.
In the lactating cow the myoepithelial cells, which cover the alveoli of the mammary glands, are contracted by the influence of oxytocin and the milk is passed into the milkducts.
The veterinary medicinal product is a sterile, aqueous, protein-free injectable solution of synthetic oxytocin which corresponds chemically as well as pharmacologically with naturally occurring oxytocin.
Pharmacokinetic particulars
Following injection, oxytocin has a rapid onset of activity as physiological effects are usually detected within minutes following administration. Oxytocin is cleared very fast, as its mean half-life of distribution is about 2 minutes while its half-life of elimination is around 12 minutes.
Pharmaceutical particulars
List of excipients
Chlorobutanol Hemihydrate
Acetic Acid, Glacial
Ethanol 96 %
Water for Injections
Major Incompatibilities
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale: 18 months
Shelf-life after first opening the immediate packaging: 7 days
Special precautions for storage
Keep the container in the outer carton in order to protect from light.
Store in a refrigerator (2°C – 8°C).
Once opened do not store above 25°C.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
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Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a valid signed and dated prescription.
Pick up
We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
