Item Number: OSTEOPEN
For the treatment of lameness and pain of degenerative joint disease/osteoarthritis (non-infectious arthrosis) in the skeletally mature dog.
Dosage and administration
3 mg pentosan polysulphate sodium / kg bodyweight (equivalent to 0.3 ml/10kg bodyweight) on four occasions, with an interval of 5-7 days.
Administer by aseptic subcutaneous injection only. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.
To establish the appropriate dosage, the weight of the individual animal should be determined prior to administering the veterinary medicinal product.
Contra-indications, warnings, etc
•Do not use in the treatment of septic arthritis. In this case, appropriate antimicrobial therapy should be instigated.
•Do not use in dogs with advanced liver or kidney impairment, or evidence of infection.
•Do not use in known cases of hypersensitivity to the active substance or to any of the excipients.
•Do not use in the skeletally immature dog (i.e. dogs whose long bone growth plates have not closed).
•As pentosan polysulphate has an anticoagulant effect, do not use in dogs with blood disorders, coagulation disorders, bleeding, trauma or malignancy (especially haemangiosarcoma) or during the peri-operative period within 6 – 8 hours of surgery..
•Do not use in arthritides of immunological origin (e.g. rheumatoid arthritis).
Special warnings for each target species
A clinical effect may not be observed until after the second injection of the course of treatment.