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Mastiplan LC 300mg/20mg (Cefapirin/Prednisolone) Pack 20

Item Number: MASTIPLAN

Mastiplan LC 300mg/20mg (Cefapirin/Prednisolone) Pack 20

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Mastiplan LC 300mg/20mg (Cefapirin/Prednisolone), intramammary suspension for lactating cows. Pack of 20.


One 10 ml syringe of 8 g oily suspension contains 300 mg cefapirin as sodium salt and 20 mg prednisolone.


Treatment of clinical mastitis in lactating dairy cows caused by Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis and Escherichia coli sensitive to cefapirin.

Dosage and administration

The contents of one syringe should be infused into each affected quarter via the teat canal, immediately after milking, at 12 hour intervals for four consecutive milkings. Each syringe contains 300 mg cefapirin and 20 mg prednisolone.

Before infusion, the udder should be milked out completely. The teat and its orifice should be thoroughly cleaned and disinfected with the cleaning towel provided. Care should be taken to avoid contamination of the syringe nozzle. Break the top of cap and gently insert either about 5 mm or remove whole cap and gently insert the total length of the nozzle into the teat canal. Infuse the total content of the syringe into the quarter.

Disperse the product by gentle massage of the teat and the udder of the affected cow.

Contra-indications, warnings, etc

Do not use in animals which are known to be hypersensitive to cephalosporin antibiotics, other ß-lactam antibiotics or to any other ingredients.

Do not use the cleaning towels on teats with open wounds.

Use of the product should be based on susceptibility testing and take into account official and local antimicrobial policies.

The syringe must only be used once for one teat.

Special precautions to be taken by the person administering the medicinal product to animals

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised to penicillins or cephalosporins or if you have been advised not to work with such preparations.

Handle this product with care to avoid exposure, taking all recommended precautions.

If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the Doctor this warning. Swellings of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

Wash hands after using the cleaning towels and wear protective gloves if skin irritation due to isopropyl alcohol is known or suspected.

Use during pregnancy or lactation

The veterinary medicinal product is intended for use during lactation. Laboratory studies in mice, rats, rabbits, and hamsters have not produced any evidence of a teratogenic, foetotoxic, maternotoxic effects. There is no evidence of reproductive toxicity (including teratogenicity) in cattle. Because no specific studies have been performed in the target animal species, use only according to the benefit/risk assessment by the responsible veterinarian during pregnancy and in breeding animals.

Withdrawal periods

Meat and offal: 4 days (96 hours)

Milk: 5.5 days (132 hours)

For animal treatment only. Keep out of the reach and sight of children.

Pharmaceutical precautions

Do not store above 25°C.

Keep the syringes in the outer carton box.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

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Packaging Quantities

Box of 1 sachet of 4 syringes and 4 cleaning towels.

Box of 1 sachet of 20 syringes and 20 cleaning towels.