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Lincoject 10% w/v Solution for Injection 100ml

Item Number: LINCOJECT

Lincoject 10% w/v Solution for Injection 100ml

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Description

In dogs and cats, Lincoject is recommended for the treatment of infections caused by Lincomycin susceptible Gram-positive organisms, particularly streptococci and staphylococci and certain Gram-negative anaerobic bacteria (e.g. Bacteroides, Fusobacterium species).

Lincoject is recommended for treatment of the following conditions in dogs and cats: Tonsillitis, laryngitis and other respiratory tract infections; abscesses, infected wounds and purulent dermatitis; septicaemia.

In pigs, Lincoject is indicated for the treatment of infections caused by Lincomycin susceptible Gram-positive organisms (e.g. staphylococci, streptococci), certain Gram-negative anaerobic organisms (e.g. Serpulina (Treponema) hyodysenteriae, Bacteroids, Fusobacterium and Mycoplasma species).

Lincoject is recommended for treatment of the following conditions in pigs: Swine dysentry, enzootic or mycoplasmal pneumonia, septic arthritis, foot abscesses.


Data Sheets

Lincoject 10 % w/v Solution for Injection Species:Cats, Dogs, Pigs

Therapeutic indication:Pharmaceuticals: Antimicrobials: Injections

Active ingredient:Lincomycin

Product:Lincoject 10% w/v Solution for Injection

Product index:Lincoject Injection

Pig - meat:3 days

Qualitative and quantitative composition

Active substance:

Lincomycin 10.0% w/v [100 mg/ml]
(as Lincomycin hydrochloride) 11.34% w/v [113.4 mg/ml]
Excipients:
Benzyl Alcohol 0.9% w/v [9mg/ml]
For a full list of excipients, see section Pharmaceutical Particulars
Pharmaceutical form

Solution for Injection.

A clear, colourless solution for injection.

Clinical particulars

Target species

Pigs, Dogs, Cats

Indications for use, specifying the target species

In dogs and cats, Lincoject is recommended for the treatment of infections caused by Lincomycin susceptible Gram-positive organisms, particularly streptococci and staphylococci and certain Gram-negative anaerobic bacteria (e.g. Bacteroides, Fusobacterium species).

Lincoject is recommended for treatment of the following conditions in dogs and cats: Tonsillitis, laryngitis and other respiratory tract infections; abscesses, infected wounds and purulent dermatitis; septicaemia.

In pigs, Lincoject is indicated for the treatment of infections caused by Lincomycin susceptible Gram-positive organisms (e.g. staphylococci, streptococci), certain Gram-negative anaerobic organisms (e.g. Serpulina (Treponema) hyodysenteriae, Bacteroids, Fusobacterium and Mycoplasma species).

Lincoject is recommended for treatment of the following conditions in pigs: Swine dysentry, enzootic or mycoplasmal pneumonia, septic arthritis, foot abscesses.

Contraindications

The use of Lincoject is not recommended in species other than the cat, dog and pig. Lincosamides may cause fatal enterocolitis in horses, rabbits and rodents and diarrhoea and reduced milk production in cattle.

Lincoject should not be given to animals with a known pre-existing monilial infection.

Not to be used in animals hypersensitive to Lincomycin

Special Warnings for each target species

When treating groups of pigs, the use of a multiple dose syringe is recommended. To refill the syringe, the use of a draw-off needle is recommended to avoid excessive broaching of the stopper.

Special precautions for use

Special precautions for use in animals

Do not exceed the recommended dosage.

Practice aseptic injection techniques.

Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local epidemiological information.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Avoid contact with the product. In case of accidental eye or skin contact, wash off the affected area thoroughly with water.

Adverse reactions (frequency and seriousness)

The intramuscular administration of Lincoject to pigs at higher levels than recommended may result in diarrhoea and loose stools.

Use during pregnancy, lactation or lay

Not applicable.

Interaction with other medicinal products and other forms of interaction

Not compatible with penicillin and erythromycin if used concurrently.

Amounts to be administered and administration route

Lincoject is indicated for intravenous and intramuscular administration to dogs and cats and intramuscular administration to pigs.

CATS AND DOGS:

Intramuscularly: 22 mg/kg of bodyweight once daily or 11 mg/kg every

12 hours.

Intravenously: 11 to 22 mg/kg one or two times per day by slow intravenous injection.

PIGS:

Intramuscularly: 4.5 to 11 mg/kg of bodyweight once daily.

To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.

Overdose (symptoms, emergency procedures, antidotes), if necessary

The intramuscular administration of Lincoject to pigs at higher levels than recommended may result in diarrhoea and loose stools.

Withdrawal period

Animals must not be slaughtered for human consumption during treatment.

Pigs (Meat): 3 days

Pharmacological particulars

Pharmacotherapeutic group: Antibiotic

ATC Vet Code: QJ01FF02

Pharmacodynamic properties

The mode of action is inhibition of protein synthesis at the ribosomal 50S subunit level. Lincomycin is primarily excreted in the faeces as both parent compound and metabolites with large biliary contribution. After administration of the recommended single dosage, faecal excretion accounts for 38% and urinary excretion for 49% of the total dose. The antibiotic is transported in polymorphonuclear leucocytes to the site of infection, an event that may explain the efficient penetration and targeting of organisms in tissues difficult to reach by diffusion in the presence of purulent material.

Pharmaceutical particulars

List of excipients

  • Benzyl Alcohol
  • Water for Injections
  • Incompatibilities

    None known

    Shelf life

    Shelf life of the veterinary medicinal product as packaged for sale: 2 Years.

    Shelf life after first opening the immediate packaging: 28 Days.

    Special precautions for storage

    Do not store above 25°C. Protect from light.

    Following withdrawal of the first dose use the product within 28 days. Discard unused product.

    Nature and composition of immediate packaging

    50 ml and 100 ml Type I clear colourless glass vials, complete with bromobutyl bungs and aluminium caps.

    Not all pack sizes may be marketed.

    Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products

    Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

    Marketing Authorisation Holder (if different from distributor)

    Norbrook Laboratories Limited, Station Works, Camlough Road, Newry, Co. Down, BT35 6JP Northern Ireland

    Marketing Authorisation Number

    Vm 02000/4183

    Significant changes

    Date of the first authorisation or date of renewal

    20th November 2001

    Date of revision of the text

    13th November 2008

    Any other information

    Nil.

    Legal category

    Legal category:POM-V

    GTIN

    GTIN description:Lincoject 50ml

    GTIN:5023534003021

    GTIN description:Lincoject 100ml

    GTIN:5023534003038

    Delivery

    Shipping charges mainland UK zone1

    ValueWeightDelivery Charge
    Over £49.00Any WeightFREE
    Under £49.00No weight limit£4.50
    Under £49.00Under 250g£2.99

    Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

    NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

    Estimated "Usually shipped in" information is shown against most products

    Overseas orders

    Postage outside of the UK is from £4.50

    Prescription Items

    Prescription items will be sent on receipt of a valid signed and dated prescription.

    Pick up

    We offer a pickup service for orders placed over the phone.

    Please ring us on 01833 641112 for more information.

    Refrigerated Items

    Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

    Returns

    We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.

    *Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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