*Images are for illustrative purposes only

Finilac 50 microgram/ml Oral Solution for Dogs and Cats

Dechra

Item no: FINILACO
 
Prescription Medicine
Option
  • Select Option
  • 10ml
  • 15ml
  • 25ml
  • 3ml
Max 1 per customer
£12.75 - £68.29
Adding to basket… The item has been added
Browse other products from the Dechra range
Clinical particulars
Target species
Dogs, Cats.
Indications for use
Treatment of false pregnancy in bitches.
Suppression of lactation in bitches and queens.
Contraindications
Do not use in pregnant animals since the product may cause abortion.
Do not use with dopamine antagonists.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Cabergoline may induce transient hypotension in treated animals. Do not use in animals currently being treated with hypotensive drugs. Do not use directly after surgery whilst the animal is still under the influence of anaesthetic agents.
Special warnings for each target species
Additional supportive treatments should involve restriction of water and carbohydrate intake and increased exercise.
Special precautions for use in animals
Caution is recommended in animals with significantly impaired liver function.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Wash hands after use.
Avoid contact with skin and eyes. Wash off any splashes immediately.
Women of childbearing potential and breast-feeding women should not handle the product or should wear impervious gloves when administering the product.
If you know you are hypersensitive to cabergoline or any of the other ingredients in the product, you should avoid contact with the product.
Do not leave unattended filled syringes in the presence of children. In the event of accidental ingestion, particularly by a child, seek medical attention immediately and show the package leaflet or the label to the physician.
Adverse reactions
In very rare cases a transient hypotension may occur.
Possible adverse effects are:
- sleepiness
- anorexia
- vomiting
These adverse effects are usually of a moderate and transient nature. Vomiting usually only occurs after the first administration. In this case treatment should not be stopped, since the vomiting is unlikely to reoccur after the following administrations. In very rare cases allergic reactions may occur, such as oedema, urticaria, dermatitis and pruritus. In very rare cases neurological symptoms may occur, such as sleepiness, muscle tremor, ataxia, hyperactivity and convulsions.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Use during pregnancy and lactation
Cabergoline has the capacity to cause abortion in the later stages of pregnancy and should not be used in pregnant animals. Differential diagnosis between pregnancy and false pregnancy should be made correctly.
The product is indicated for the suppression of lactation: inhibition of prolactin secretion by cabergoline results in a rapid cessation of lactation and a reduction in the size of the mammary glands. The product should not be used in lactating animals unless suppression of lactation is required.
Interactions
Since cabergoline exerts its therapeutic effect by direct stimulation of dopamine receptors, the product should not be administered concurrently with drugs which have dopamine antagonist activity (such as phenothiazines, butyrophenones, metoclopramide), as these might reduce its prolactin inhibiting effects. See also Contraindications.
Since cabergoline may induce transient hypotension, the product should not be used in animals concurrently treated with hypotensive drugs. See also Contraindications and Adverse reactions.
Amounts to be administered and administration route
The product should be administered orally either directly into the mouth or by mixing with food.
The dosage is 0.1 ml/kg body weight (equivalent to 5 microgram/kg body weight of cabergoline) once daily for 4-6 consecutive days, depending on the severity of the clinical condition.
If the signs fail to resolve after a single course of treatment, or if they recur after the end of treatment, then the course of treatment may be repeated.
The weight of treated animal should be accurately determined before administration.
Overdose
The experimental data indicate that a single overdose with cabergoline might result in an increased likelihood of post-treatment vomiting, and possibly an increase in post-treatment hypotension.
General supportive measures should be undertaken to remove any unabsorbed drug and maintain blood pressure, if necessary. As an antidote, the parental administration of dopamine antagonist drugs such as metoclopramide might be considered.
Pharmacological particulars
Pharmacotherapeutic group: prolactin inhibitors, cabergoline.
ATCvet code: QG02CB03
Pharmacodynamic properties
Cabergoline is an ergoline derivative. It has dopaminergic activity which leads to inhibition of prolactin secretion by the anterior pituitary. The mechanism of action of cabergoline was studied in in vitro and in vivo models. The most important details are outlined below:
- Cabergoline inhibits prolactin secretion by the pituitary gland and inhibits all prolactin dependent processes, such as lactation. Maximum inhibition is achieved after 4-8 hours and lasts several days depending on the administered dose.
- Cabergoline has no other effects on the endocrine system besides the inhibition of prolactin secretion.
- Cabergoline is a dopamine agonist in the central nervous system by selective interaction with the dopaminergic D2 receptors.
- Cabergoline has affinity for the noradrenergic receptors, however, this does not cause interference with the noradrenalin and serotonin metabolism.
- Cabergoline is an emetic, like the other ergoline derivatives (in potency comparable to bromocriptine and pergolide).
Pharmacokinetic properties
No pharmacokinetic data are available for the recommended dosing regimen in dogs and cats.
Pharmacokinetic studies in dogs were performed with a daily dose of 80 µg/kg body weight (16 times the recommended dose). Dogs were treated for 30 days; pharmacokinetic assessments made on day 1 and 28.
Absorption:
- Tmax = 1 hour on day 1 and 0.5-2 hours (mean 75 minutes) on day 28;
- Cmax ranged from 1140-3155 pg/ml (mean 2147 pg/ml) on day 1 and from 455-4217 pg/ml (mean 2336 pg/ml) on day 28;
- AUC (0-24 hours) on day 1 ranged from 3896-10216 pg.h.ml-1 (mean 7056 pg.h.ml-1) and on day 28 from 3231-19043 pg.h.ml-1 (mean 11137 pg.h.ml-1).
Elimination:
Plasma half life in dogs t½ on day 1~19 hours; t½ on day 28~10 hours.
Pharmaceutical particulars
Incompatibilities
The veterinary medicinal product must not be mixed with other aqueous solutions (e.g. milk).
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf life after first opening the immediate packaging: 28 days.
Special precautions for storage
Do not store above 30 °C.
Keep the bottle in the outer carton in order to protect from light.
Immediate packaging
3 ml (in a bottle of 5 ml capacity), 10 ml, 15 ml, 25 ml and 50 ml brown Type III glass bottle closed by a conical ‘Luer slip' syringe adapter (low density polyethylene) and a screw cap (high density polyethylene). The bottles are packed in a cardboard box.
The 1 ml and 2.5 ml plastic syringes will be enclosed in all package sizes.
Not all pack sizes may be marketed.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

Related Products