Uses
Duphatrim IS is a broad-spectrum antibacterial indicated in the treatment of a wide range of Gram-positive and Gram-negative organisms.
The two active ingredients, trimethoprim and sulfadiazine, sequentially block bacterial and protozoal synthesis of folinic acid, thus greatly potentiating the activity obtained when either ingredient is used alone.
In vitro antibacterial activity of Duphatrim IS is extensive, including Actinobacillus spp, Actinomyces spp, Bordetella spp, Brucella spp, Corynebacterium spp, E. coli, Haemophilus spp, Klebsiella spp, Pasteurella spp, Pneumococcus spp, Proteus spp, Salmonella spp, Staphylococcus spp (including penicillin-sensitive and penicillin-resistant), Streptococcus spp.
Duphatrim IS is indicated for use in horses, cattle, pigs, dogs and cats, for the treatment of acute, subacute and chronic bacterial infections sensitive to trimethoprim/sulfadiazine therapy such as:
Bacterial infections of the respiratory tract, including rhinitis, pneumonia, bronchitis and in bacterial infections secondary to viral disease such as viral pneumonia or mycoplasma infections.
Urogenital tract infections, including cystitis, vaginitis, urethritis, nephritis and metritis.
Alimentary tract infections, including neonatal diarrhoea and salmonellosis.
Other infections, such as foul-in-the-foot, severe mastitis, bacterial agalactia of sows, infections of the eye, ear or mouth.
Dosage and administration
Cattle and pigs:
The recommended dose rate is 15mg of active ingredients per kilogram bodyweight (1ml per 16kg bodyweight) once by intramuscular or slow intravenous injection, but in severe infections it may be repeated daily until 2 days after symptoms resolve up to a maximum of 5 days.
Duphatrim IS may be administered by intravenous injection when rapid blood levels of trimethoprim and Sulfadiazine are required.
Horses:
The recommended dose rate is 15mg of active ingredients per kilogram bodyweight (1ml per 16 kg bodyweight), by slow intravenous injection.
Dogs and Cats:
The recommended dose rate is 30mg of active ingredients per kilogram bodyweight (1ml per 8kg bodyweight), by subcutaneous injection only.
The recommended site in dogs is the loose skin at the top of the neck.
A single injection may be sufficient in uncomplicated conditions, but in severe infections it may be repeated daily for up to 5 days or until 2 days after the symptoms have resolved.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.
Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a valid signed and dated prescription.
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We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
