Dorbene vet 1mg/ml solution for injection for dogs and cats.
Uses
In dogs and cats: Sedation to facilitate handling. Premedication prior to general anaesthesia.
In cats: In combination with ketamine for general anaesthesia for minor surgical procedures of short duration.
Dosage and administration
Dorbene vet 1mg/ml is intended for:
Dogs: Intramuscular or intravenous injection.
Cats: Intramuscular and subcutaneous injection.
Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes.
Dogs: For sedation Dorbene vet should be administered at the rate of 750 µg medetomidine hydrochloride i.v. or 1000 µg medetomidine hydrochloride i.m. per square metre of body surface, corresponding to dose of 20-80 µg medetomidine hydrochloride per kg body weight.
Use the table to determine the correct dosage on the basis of body weight.
Maximal effect is obtained within 15-20 minutes. Clinical effect is dose-dependent, lasting from 30 – 180 minutes.
Dorbene vet 1 mg/ml dosages for sedation in ml and corresponding amount of medetomidine hydrochloride in µg /kg bw. For pre-medication use 50% of the dose indicated in the table.
| Bodyweight (kg) | Intravenous injection (ml) | Corresponding (to µg/kg bw) | Intramuscular injection (ml) | Corresponding (to µg/kg bw) |
| 1 | 0.08 | 80.0 | 0.10 | 100.0 |
| 2 | 0.12 | 60.0 | 0.16 | 80.0 |
| 3 | 0.16 | 53.3 | 0.21 | 70.0 |
| 4 | 0.19 | 47.5 | 0.25 | 62.5 |
| 5 | 0.22 | 44.0 | 0.30 | 60.0 |
| 6 | 0.25 | 41.7 | 0.33 | 55.0 |
| 7 | 0.28 | 40.0 | 0.37 | 52.9 |
| 8 | 0.30 | 37.5 | 0.40 | 50.0 |
| 9 | 0.33 | 36.7 | 0.44 | 48.9 |
| 10 | 0.35 | 35.0 | 0.47 | 47.0 |
| 12 | 0.40 | 33.3 | 0.53 | 44.2 |
| 14 | 0.44 | 31.4 | 0.59 | 42.1 |
| 16 | 0.48 | 30.0 | 0.64 | 40.0 |
| 18 | 0.52 | 28.9 | 0.69 | 38.3 |
| 20 | 0.56 | 28.0 | 0.74 | 37.0 |
| 25 | 0.65 | 26.0 | 0.86 | 34.4 |
| 30 | 0.73 | 24.3 | 0.98 | 32.7 |
| 35 | 0.81 | 23.1 | 1.08 | 30.9 |
| 40 | 0.89 | 22.2 | 1.18 | 29.5 |
| 50 | 1.03 | 20.6 | 1.37 | 27.4 |
| 60 | 1.16 | 19.3 | 1.55 | 25.8 |
| 70 | 1.29 | 18.4 | 1.72 | 24.6 |
| 80 | 1.41 | 17.6 | 1.88 | 23.5 |
| 90 | 1.52 | 16.9 | 2.03 | 22.6 |
| 100 | 1.63 | 16.3 | 2.18 | 21.8 |
For premedication Dorbene vet 1 mg/ml should be administered at a dosage of 10-40 µg medetomidine hydrochloride per kg body weight, corresponding to 0.1-0.4 ml Dorbene vet 1 mg/ml per 10 kg body weight. The exact dose depends on the combination of drugs used and the dosage(s) of the other drug(s). The dose should furthermore be adjusted to the type of surgery, length of procedure and patient temperament and weight. Premedication with medetomidine will significantly reduce the dosage of the induction agent required and will reduce volatile anaesthetic requirements for maintenance anaesthesia. All anaesthetic agents used for induction or maintenance of anaesthesia should be administered to effect. Before using any combinations, product literature for the other products should be observed.
Cats: For moderate-deep sedation and restraint of cats Dorbene vet 1 mg/ml should be administered at a dosage of 50 – 150 µg medetomidine hydrochloride / kg bw (corresp. to 0.05 – 0.15 ml Dorbene vet 1 mg/ml / kg bw). The speed of induction is slower when subcutaneous route of administration is used. For anaesthesia Dorbene vet 1 mg/ml should be administered at a dosage of 80 µg medetomidine hydrochloride / kg bw (corresp. to 0.08 ml Dorbene vet 1 mg/ml / kg bw) and 2.5 to 7.5 mg ketamine / kg bw. Using this dosage anaesthesia occurs within 3 – 4 minutes and is apparent for 20 – 50 minutes. For longer lasting procedures administration has to be repeated by using ½ of the initial dose (i.e. 40 µg medetomidine hydrochloride (corresp. to 0.04 ml Dorbene / kg bw) and 2.5 - 3.75 mg ketamine / kg bw) or 3.0 mg ketamine / kg bw alone. Alternatively, for longer lasting procedures anaesthesia may be extended by use of the inhalation agents isoflurane or halothane, with oxygen or oxygen/nitrous oxide.
Animals should be fasted 12 hours before anaesthesia.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
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