Item Number: ADRENACAINE
Indications for use, specifying the target species
The product is indicated for use in minor surgical procedures particularly dehorning and disbudding in cattle.
Do not administer by intravenous, intra-articular or epidural injection.
Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
Special Warnings for each target species
Special precautions for use
Special precautions for use in animals
Care should be taken not to inject the product intravascularly.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Care should be taken to avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or label to the physician. Immediately wash off any splashes to the eyes or skin with copious amounts of water.
Seek medical attention if irritation occurs.
Wash hands after use.
Adverse reactions (frequency and seriousness)
Use during pregnancy, lactation or lay
The product can be administered at any stage of pregnancy or lactation.
Interaction with other medicinal products and other forms of interaction
Procaine may inhibit the action of sulfonamides and their concurrent administration should be avoided.
Amounts to be administered and administration route
The product should be administered by subcutaneous injection as follows:
Cattle: 2-5 ml
Avoid excessive broaching.
Do not exceed the recommended dose.
Overdose (symptoms, emergency procedures, antidotes), if necessary
The product is well tolerated at doses up to 3 times the recommended dose for cattle.
Local anaesthetics used in excess can cause systemic toxicity characterised by CNS effects. If systemic toxicity occurs, as a result of inadvertent intra-vascular injection, the administration of oxygen to treat cardio-respiratory depression and diazepam to control convulsions should be considered.
Meat and offal: Zero days
Milk: Zero hours
Pharmacotherapeutic group: Anaesthetic
ATC Vet Code: QN01BA52
Procaine (p-aminobenzoyl-diethyl aminoethanol) is an amino ester. Procaine, a local anaesthetic shares with other chemical families the ability to act as a membrane stabiliser, by interfering with the ability of excitable cells to generate or transmit impulses. Procaine blocks conduction by decreasing or preventing the large transient increase in the permeability of excitable membranes to Na+ that is produced by a slight depolarisation. The action of local anaesthetics is due to their direct interaction with voltage sensitive Na+ channels.
Adrenaline is composed of two major constituents, the aromatic portion of the molecule consists of 1,2-dihydroxybenzene (catechol), the aliphatic portion consists of ethanol-amine.
The duration of the action of local anaesthetics is proportional to the time which they are in actual contact with nervous tissue. Consequently procedures which localise the drug at the nerve greatly prolong the period of anaesthesia. It has been demonstrated that the addition of epinephrine to local anaesthetic solutions greatly prolongs and intensifies their action. Epinephrine performs a dual service. By decreasing the rate of absorption it not only localises the anaesthetic agent at the desired site but also allows the rate at which the anaesthetic is destroyed in the body to keep pace with the rate at which it enters the circulation. This greatly reduces systemic toxicity.
Procaine Hydrochloride is a local anaesthetic. The in-vitro half-life of in plasma is less than 1 minute. It is only slightly bound to plasma protein (5.8%) and has a duration of anaesthetic effect of about 50 minutes in man. Adrenaline is added to local anaesthetics such as Procaine Hydrochloride to slow diffusion and limit absorption as it constricts arterioles and capillaries, so prolonging the duration of the effect and lessening the danger of toxicity.
List of excipients
Sodium Metabisulphite (E223)
Sodium Hydroxide (pH adjustment)
Hydrochloric Acid (pH adjustment)
Water for Injections
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years
Shelf-life after first opening the immediate packaging: 28 days
Special precautions for storage
Do not store above 25°C.
Protect from light.
Nature and composition of immediate packaging
The product will be supplied in 100 ml amber type I glass vials with bromobutyl bungs and aluminium caps.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
ADRENACAINE: Data Sheet
Shipping charges mainland UK zone1
|Over £49.00||Any Weight||FREE|
|Under £49.00||No weight limit||£4.50|
|Under £49.00||Under 250g||£2.99|
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.
NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.
Estimated "Usually shipped in" information is shown against most products
Postage outside of the UK is from £4.50
Prescription items will be sent on receipt of a valid signed and dated prescription.
We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email [email protected] to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
There have been no questions/answers for this product so far.
fast easy service. would use again
Reviewed on: 01 May 2018
Product Variant: ADRENACAINE
Reviewed on: 02 November 2013
Product Variant: ADRENACAINE
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