Zylkene Capules

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Zylkene Capules

Average Rating 5/5 (66 reviews)    
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Item Number: ZYLKENE 
Phone orders quick webcode: D11778

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450mg (pack of 20) £31.35 Usually despatched within 24-48 hours
75mg (pack of 20) £10.19 In Stock
225mg (pack of 20) £18.25 Usually despatched within 24-48 hours



1). You are ordering a PRESCRIPTION ONLY medicine. Please do NOT continue unless you are sending us a valid prescription from your vet.

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Zylkène is a novel product, which is proven to help manage stress in dogs and cats.
There are many common causes of stress for dogs and cats, as for their owners! Many animals (especially cats) find change difficult to deal with and Zylkène can help facilitate adaptation to change.

Common causes of stress include:
Moving house
Arrival of a new baby or a new pet
A new cat moving into the outside territory
Sudden noise e.g. fireworks or thunderstorms
Cattery or Kennel stay
Many cats also find living with other cats stressful

Dogs and cats obviously cannot tell us how they are coping, but they can alter their behaviour. There are many different ways pets can show stress including:
Posture changes e.g. crouching, dilated pupils
Changed demeanour
House soiling
Changes use of their environment e.g. changed resting place, reduced exploration or stopped visiting a certain part of the house
Changes in pattern of sleeping
Habits such as excessive licking and grooming
Reduced play
Changed interaction with humans or other pets – can be increased or decreased

Some signs are more easily recognised than other – cats in particular show stress by ‘withdrawal’ behaviours such as hiding more and resting on a higher surface e.g. top of wardrobe rather than a chair.

Some of these behaviours can also have a medical cause so it is very important to see your vet to you discuss if Zylkène is suitable for your pet.

Zylkène comes in capsules which are colour coded for size. It only needs to be given once daily, and is easy to give. Simply open the capsule, and mix the palatable powder with food or a treat. Zylkène has not been associated with any side effects.

Behaviour modification techniques can also help
your pet to deal with stress – ask your vet or
behaviouralist for advice.

What is Zylkene?

Zylkene is a natural product, proven to help manage stress in cats and dogs. Zylkene quickly helps pets to cope with many challenging situations and can facilitate adaption to change.

Zylkene contains the globally patented bioactive decapeptide a-casozepine, derived from milk protein casein.

No side effects have been associated with the use of Zylkene and it can be given with other products.

Zylkene is non-chemically manufactured to human pharmaceutical standards (GMP) and the final product is hypoallergenic, preservative free and lactose free.


Zylkene is palatable and easy to give- open the capsule and mix the water- soluble powder with food or a treat such as cheese or tuna. The capsules can also be given whole.

The average daily intake required is 15mg/kg, given once daily. The pets behaviour should be re-evaluated after a 15-30 day course and the daily intake modfied if necessary.

How do I use Zylkene?

For short term stress, e.g. kennelling, begin Zylkene one day before the anticipated stressful situation and continue for the duration of the stress.

Zylkene can help manage long term stress. The initial period of use should be 1-2 months, and can be repeated as required.

Behaviour modification techniques will also aid the management of stress-related behavioural problems in dogs and cats.

Dosage and Admin:

Up to 5kg (11lb)- give one 75mg capsule daily
5-10kg (11-22lb)- give two 75mg capsules daily
10-20kg (22-44lb)- give one 225mg capsule daily
20-40kg (44-88lb)- give one 450mg capsule daily
Over 40kg (88lb)- give two 450mg capsules daily


Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.99
Under £49.00 No weight limit £4.99

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 feefoProduct Reviews

Zylkene Capules 75mg (pack of 20)

The only thing that disappointed me was although my dog was a lot calmer he did still exhibit signs of stress.

Zylkene Chews (pack of 14) 75mg (dogs & cats <10kg)

Again it works well.

Zylkene Capules 75mg (pack of 20)

Can’t get either of my cats to take this no matter how devious I try to be.

Zylkene Capules 75mg (pack of 20)

Great product, I have a very nervous cat and this is great for when I give her a good groom and its great for fireworks.

Zylkene Capules 225mg (pack of 20)

Zylkene calmed the dog as expected.

Zylkene Capules 225mg (pack of 10)

My dog is old these tablets appear to help him with his arthiritus

Zylkene Capules 225mg (pack of 100)

Quick delivery good product

Zylkene Capules 225mg (pack of 10)

Because they always deliver what is promised

Zylkene Capules 225mg (pack of 20)

Initially recommended by my vet, this product does exactly what it says on the box and I had a much calmer pet during a very stressful time for him.

Zylkene Capules 225mg (pack of 20)

It deems to be working, there definitely an improvement

Zylkene Equine 1000mg Pack of 20 sachets

A great calmer, which worked well on both pony's a mare and a gelding.

Zylkene Capules 225mg (pack of 20)

Because they have settled my dog a lot and would definitely purchase both again.

Zylkene Equine 1000mg Pack of 20 sachets

Definitely helps my nervous mare. Calms but doesn't drug.

Zylkene Capules 450mg (pack of 10)

These were fine, but carriage costs and vat make the price probably higher that your competitors.

Zylkene Capules 75mg (pack of 100)


Zylkene Capules 75mg (pack of 20)

I don't think this works. Have tried and not seen any difference. Serene-um much better

Zylkene Capules 75mg (pack of 10)

This product actually worked for my dog on new years eve, usually bonfire night and any fireworks or thunder she is terrified, gave her one a day a week before and the difference was unbelievable, she never bothered with them and they are non drowsy so there is no difference in your dog

Zylkene Equine 1000mg Pack of 20 sachets

Worked well for my horse on stall rest.

Zylkene Capules 225mg (pack of 10)

Does see to have an effect but a bit expensive.

Zylkene Capules 225mg (pack of 10)

I think they helped. Used along side the Adaptil Diffuser.

Zylkene Capules 450mg (pack of 10)

Did not work at all for my Border Collie

Zylkene Capules 450mg (pack of 10)

This product was recommended by a friend. I tried it, it was OK but not quite the result hoped for, plus rather expensive.

Zylkene Capules 225mg (pack of 10)


Zylkene Capules 75mg (pack of 10)

As Above

Zylkene Capules 225mg (pack of 10)

Good product. Would use again.

Zylkene Equine 1000mg (pack of 20 sachets)