Zanil Fluke Drench 34 mg/ml Oral Suspension 5L.
Cattle and sheep.
Indications for use:
For the treatment and control of chronic fascioliasis in cattle and sheep.
It removes practically all flukes (Fasciola spp.) present in the bile ducts of the liver.
Do not use in sheep producing milk for human consumption.
Do not use in cases of hypersensitivity to the active substance.
Special warnings for each target species:
At normal dose levels, oxyclozanide is not active against immature flukes present in liver tissue.
Milking cattle, particularly high yielders, may occasionally show a reduction in yield of 5% or more for about 48 hours after handling. The effect of this small loss may be minimised by spreading herd dosing over a period of about a week.
Special precautions for use:
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
•Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
•Underdosing, which may be due to underestimation of body weight, misadministration of the product or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigates using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmaceutical class and having a different mode of action should be used.
To date no resistance to oxyclozanide has been reported. Use of the product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Care should be taken when administering by dosing gun.
Due regard must be given to the physical condition of the animals undergoing treatment, particularly those in advanced pregnancy and / or under stress from adverse weather conditions, poor nutrition, penning, handling etc.
Do not eat, drink or smoke when using this product.
Wash splashes from eyes and skin immediately.
Take off any contaminated clothing immediately.
User should wear chemical resistant gloves during administration of the product.
Wash hands and exposed skin before meals and after work.
At normal oxyclozanide dose levels, cattle may show slight softening of the faeces with the occasional animal showing increased frequency of defecation and transient inappetence. The effects of oxyclozanide overdosage are dullness and some loosening of faeces in sheep and possible diarrhoea, inappetance and loss of weight in cattle. These effects are occasionally enhanced in animals with severe liver damage and/or dehydration at the time of dosing.
Use during pregnancy, lactation or lay:
The product may be given to young, pregnant and lactating animals.
Amounts to be administered and administration route:
The product can be given to young, pregnant and lactating animals and those in debilitated condition (in the absence of inter current disease).
Give as an oral drench. Shake the product well before use.
The body weight of animals should be assessed as accurately as possible before calculating the dosage. The accuracy of the dosing device should be checked.
If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or overdosing.
Dose according to body weight at the rate of 10 mg oxyclozanide per kg body weight for cattle and 15 mg oxyclozanide per kg body weight for sheep as follows:
Cattle : 3 ml per 10 kg body weight.
|50 kg (approx. 1 cwt)||15 ml|
|100 kg (approx. 2 cwt)||30 ml|
|150 kg (approx. 3 cwt)||45 ml|
|200 kg (approx. 4 cwt)||60 ml|
|250 kg (approx. 5 cwt)||75 ml|
|300 kg (approx. 6 cwt)||90 ml|
|350 kg and over (approx. 7 cwt and over)||105 ml|
Drench can be given in the feed to cattle which are fed individually. Pour the recommended dose onto their concentrate ration. Molasses or salt may be added for shy feeders.
Sheep: 4.5 ml per 10 kg body weight.
|10 kg (approx. 22 lb)||4.5 ml|
|20 kg (approx. 44 lb)||9.0 ml|
|30 kg (approx. 66 lb)||13.5 ml|
|40 kg (approx. 88 lb)||18.0 ml|
|45 kg and over (approx. 100 lb and over)||20.0 ml|
The effects of oxyclozanide overdosage are dullness and some loosening of faeces in sheep and possible diarrhoea, inappetence and loss of weight in cattle. These effects are occasionally enhanced in animals with severe liver damage and/or dehydration at the time of dosing.
Meat and offal: 28 days.
Milk: 72 hours.
Meat and offal: 28 days.
Milk: Do not use in sheep producing milk for human consumption.
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