An off-white freeze-dried pellet containing attenuated strains of BRSV (Bovine Respiratory Syncytial Virus) and PI3 (Parainfluenza type 3) viruses supplied together with a suspension containing inactivated, adjuvanted IBR (Infectious Bovine Rhinotracheitis – BHV-1) and BVD (Bovine Viral Diarrhoea) cytopathic and non-cytopathic Type 1 viruses.
For active immunisation of cattle to reduce infection, clinical signs and respiratory disease caused by Bovine Respiratory Synctial Virus (BRSV), Infectious Bovine Rhinotracheitis (IBR, caused by BHV-1) virus and Parainfluenza type 3 Virus (PI3); and leucopenia and viraemia caused by the Bovine Viral Diarrhoea (BVD) virus Type 1 cytopathic and non-cytopathic strains. A duration of immunity of at least 6 months has been demonstrated.
Dosage and administration
Reconstitute the vaccine by first shaking the vial containing the suspension, and then aseptically withdraw and add all the suspension to the vial containing the freeze-dried components. Shake well and aseptically administer 5ml intramuscularly.
For cattle over 3 months of age
Two doses of 5ml of reconstituted vaccine should be given three to four weeks apart to cattle over the age of 3 months.
Ideally, calves should be vaccinated at least 2 weeks before transport, mixing of animals of different origins, housing or any other event which may cause the animals to be stressed or exposed to new infections. Calves are usually most susceptible during early autumn. The vaccine will protect animals against BRSV, PI3, IBR and BVD for at least 6 months, which will cover the period of risk from respiratory infections.
Should cattle be at risk from these respiratory diseases at a subsequent time, the same vaccination scheme is recommended at least 14 days prior to the period of expected disease challenge.
For cattle over 3 weeks of age
For cattle from 3 weeks of age, vaccination leads to seroconversion of seronegative calves vaccinated at 3 and 6 weeks of age. The influence of maternally derived antibodies has not been studied in detail and it is therefore recommended that calves vaccinated before 12 weeks of age are re-vaccinated at 12 weeks of age.
Contra-indications, warnings, etc
Do not vaccinate pregnant animals.
Very occasionally, administration of the vaccine may be followed by a mild transient reaction at the injection site up to 0.5cm and completely resolved within 15 days.
No information is available on the safety and efficacy from the concurrent use of this vaccine with any other product except Rispoval™ Pasteurella. Therefore the safety and efficacy of this product when used with any other (either when used on the same day or at different times) has not been demonstrated.
Store away from light between + 2° and + 8°C. Do not freeze.
Reconstituted vaccine should be used within 2 hours.
Do not mix with any other vaccine/immunological product.
Dispose of waste material by boiling, incineration or immersion in an approved disinfectant in accordance with national requirements.
For animal treatment only.
Keep out of reach of children.
Vials containing 5 doses of freeze-dried component are available, together with an equal number of vials of suspension in 5 doses (25ml).
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