Piriton Syrup is indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.
Also indicated for the symptomatic relief of itch associated with chickenpox.
Adults: 10ml every 4 to 6 hourly (daily max: 24 mg i.e. 60ml)
Children aged 6 - 12 years: 5ml every 4 to 6 hourly (daily max: 12 mg i.e. 30ml)
Children aged 2 - 5 years: 2.5ml every 4 to 6 hourly (daily max: 6 mg i.e. 15ml)
Children aged 1 - 2 years: 2.5ml twice daily
Not recommended for children below 1 year
Elderly: As in adults but such patients are prone to confusional psychosis and other neurological anticholinergic effects.
Piriton Syrup is contra-indicated in patients who are hypersensitive to antihistamines or to any of the syrup ingredients.
The anticholinergic properties of chlorphenamine are intensified by monoamine oxidase inhibitors (MAOIs). Piriton Syrup is therefore contra-indicated in patients who have been treated with MAOIs within the last fourteen days.
Chlorphenamine, in common with other drugs having anticholinergic effects, should be used with caution in epilepsy; raised intra-ocular pressure including glaucoma; prostatic hypertrophy; severe hypertension or cardiovascular disease; bronchitis, bronchiectasis and asthma; hepatic disease and thyrotoxicosis. Children and the elderly are more likely to experience the neurological anticholinergic effects.
The effects of alcohol may be increased.
Piriton Syrup contains sugar. It should be administered with care to patients with diabetes mellitus. Long term use increases the risk of dental caries and it is essential that adequate dental hygiene is maintained.
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