PerMacyl Injection (Pack of 10) x 36ml

PerMacyl Injection (Pack of 10) x 36ml

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Item Number: PERMACYL 
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Unit Price:

£119.99 (Incl. Vat)

Usually despatched within 24-48 hours


NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” can only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.

You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post


PerMacyl Injection (Pack of 10) x 3.


Treatment of mastitis in lactating cows caused by Streptococcus uberis, Streptococcus dysgalactiae, Streptococcus agalactiae and Staphylococcus aureus (beta-lactamase non-producing), sensitive to penicillin.


Dosage and administration

Administer by deep intramuscular injection.

Directions for use: Reconstitute the suspension using the entire contents of the solvent vial.

Shake well after reconstitution. A minimum of 10 inversions of vials can be necessary.

Each ml of suspension contains 250,000 IU (236.3 mg) of penethamate hydriodide.

Dose: 15,000 IU (14.2 mg) of penethamate hydriodide per kg of body weight / day (equivalent to 6 ml of reconstituted medicinal product / 100 kg body weight) for three to four consecutive days. Shake well before use.

Administer the recommended daily dose every 24 hours, for three to four consecutive administrations.

To ensure administration of a correct dose, body weight should be determined as accurately as possible.

The recommended maximum volume to be administered at a single injection site is 20 ml.

The stopper should not be punctured more than 10 times.

Contra-indications, warnings, etc


Do not use in animals known to be hypersensitive to penicillins, cephalosporins, and/or any of the excipients.

Do not administer intravenously.

Do not use in lagomorphs and rodents such as guinea pigs, hamsters or gerbils.

Do not administer to animals with renal disease including anuria or oliguria.

Special warnings for each target species

Treatment should be carried out during lactation.

Special precautions for use

This veterinary medicinal product does not contain any antimicrobial preservative.

Special precautions for use in animals

Using penethamate hydriodide for the treatment of mastitis must be accompanied by hygienic measures to prevent reinfection.

Where local (regional, farm-level), epidemiological information indicate possible reduced susceptibility of the relevant strains of the bacterial species involved in mastitis, use of the product should be based on susceptibility testing on bacteria isolated from diseased animals.

The veterinary medicinal product is not effective against beta-lactamase producing organisms.

Official national and regional antimicrobial policies should be taken into account when the product is used.

Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to benzylpenicillin and may decrease the effectiveness of treatment with other beta-lactam antimicrobials due to the potential for cross-resistance.

Operator warnings

Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

Handle this product with great care to avoid exposure.

Wear gloves when handling the veterinary medicinal product to avoid contact sensitization.

In case of accidental self-injection or if you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the package leaflet or the label to the doctor

Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

Wash hands after use.

Adverse reactions (frequency and seriousness)

The symptoms of adverse reactions range from mild skin reactions such as urticaria and dermatitis to severe reactions such as anaphylactic shock with tremors, vomiting, salivation, gastrointestinal disorders and laryngeal oedema.

In some situations the treatment may lead to secondary infections due to overgrowth of non-target organisms.

Use during pregnancy, lactation or lay

Can be used during pregnancy and lactation.

Interaction with other medicinal products and other forms of interaction

The product should not be administered with antibiotics that have a bacteriostatic mode of action.

Overdose (symptoms, emergency procedures, antidotes), if necessary

In cases of overdose, adverse reactions such as those described in Adverse Reactions may occur.

Withdrawal periods

Meat and offal: 4 days

Milk: 60 hours

Pharmaceutical precautions

Before reconstitution, the powder and solvent vials do not require any special storage conditions.

The reconstituted suspension should be stored in the refrigerator (2-8°C).

Shelf life after reconsitution according to directions: 24 hours

Legal category


Packaging Quantitie

Cardboard box containing:

10,000,000 IU powder vial and 36 ml solvent vial

Powder vial: 50 ml type II colourless glass vial closed with a bromobutyl stopper and sealed with an aluminium flip-top seal. Solvent vial: 50 ml type II colourless glass vial closed with a bromobutyl stopper and sealed with an aluminium flip-top seal


Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

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