Noroprost 0.5% w/v Solution for Injection 30ml.
Indications for use, specifying the target species
Noroprost is indicated for its luteolytic effect on corpora lutea in cattle. This luteolytic action of Noroprost may be utilised as follows:
1. To improve control of the time of oestrus in cycling cattle.
2. To control breeding in cattle.
3. To induce parturition in cattle.
4. Synchronisation of recipient cattle for embryo transplantation.
5. To induce abortion in cattle.
6. To treat cattle which have a functional corpus luteum but do not express behavioural oestrus (sub-oestrus or silent heat).
7. For treatment of chronic metritis and pyometra in cattle.
8. For treatment of ovarian luteal cysts.
Do not administer by the intravenous route.
Animals should not be treated if they suffer from either acute or sub acute disorders of the vascular system, gastrointestinal tract or respiratory system.
Special Warnings for each target species
No special warnings.
Special precautions for use
Special precautions for use in animals
Noroprost is ineffective when administered prior to day 5 after ovulation. Observe aseptic precautions during use.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Prostaglandins of the F2* type can be absorbed through the skin and may cause bronchospasm or miscarriage. Care should be taken when handling the product to AVOID SELF-INJECTION OR SKIN CONTACT.
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Women of child-bearing age, asthmatics and persons with bronchial or other respiratory problems should avoid contact with, or wear disposable plastic gloves when administering, the product.
Accidental spillage on the skin should be washed off immediately with soap and water. Wash hands after use.
Adverse reactions (frequency and seriousness)
Side-effects are infrequently observed and are of a transitory nature as the compound is rapidly metabolised in the tissues. In cattle, salivation, tremor, restlessness and mild diarrhoea can occur for 15 - 30 minutes. The side-effects disappear within one hour after the administration of PGF2*
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