Modulis 100 mg/ml oral solution for dogs.
Treatment of chronic manifestations of atopic dermatitis in dogs.
Dosage and administration
For oral use.
The mean recommended dose of ciclosporin is 5 mg/kg body weight corresponding to 0.5 ml of solution for 10 kg of body weight.
The veterinary medicinal product will initially be given daily until a satisfactory clinical improvement is seen. This will generally be the case within 4 weeks. If no response is obtained within the first 8 weeks, the treatment should be stopped. Once the clinical signs of atopic dermatitis are satisfactorily controlled, the preparation can then be given every other day as a maintenance dose. The veterinarian should perform a clinical assessment at regular intervals and adjust the frequency of administration to the clinical response obtained. In some cases where the clinical signs are controlled with every-other-day dosing, the veterinarian can decide to give the veterinary medicinal product every 3 to 4 days. Adjunct treatment (e.g. medicated shampoos, essential fatty acids) may be considered before reducing the dosing interval. Treatment may be stopped when the clinical signs are controlled. Upon recurrence of clinical signs, treatment should be resumed at daily dosing, and in certain cases repeated treatment courses may be required.
The veterinary medicinal product should be given at least 2 hours before or after feeding.
The product is administered directly into the mouth.
Instructions for use
Push down and unscrew bottle top.
Insert the dosing syringe into the plastic adapter.
Turn the bottle/syringe upside down and slowly pull the plunger down until the white line on the plunger corresponds to the dose prescribed by your veterinarian. The syringe is graduated in kg and ml.
By pushing the plunger in, empty the contents of the syringe directly into the mouth. Introduce the syringe either to the side of the mouth or over the tongue.
If necessary, wipe the outside of the syringe with a dry tissue and dispose of used tissue immediately. Close the bottle and insert the syringe into the specific cap to protect from any contamination and to avoid any spillage of remaining product.
For the 5 and 15 ml vials:
Volume to be administered using 1 ml syringe: 0.05 ml/kg, i.e. 1 graduation/kg.
For the 30 and 50 ml vials:
Volume to be administered using 2 ml syringe: 0.1 ml/2 kg, i.e. 1 graduation/2 kg
Contra-indications, warnings, etc
Do not use in cases of hypersensitivity to ciclosporin or one of the excipients.
Do not use in dogs less than six months of age or less than 2 kg in weight.
Do not use in cases with a history of malignant disorders or progressive malignant disorders.
Do not vaccinate with a live vaccine during treatment or within a two-week interval before or after treatment. (see also 'Special precautions for use' and 'Interaction with other medicinal products').
5 ml bottle with 1 ml syringe in a cardboard box
15 ml bottle with 1 ml syringe in a cardboard box
30 ml bottle with 2 ml syringe in a cardboard box
50 ml bottle with 2 ml syringe in a cardboard box
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