Meflosyl 5% Solution for injection for Cattle and Horses.
Indicated for the alleviation of inflammation and pain associated with musculo-skeletal disorders and for the alleviation of visceral pain associated with colic.
Indicated for the control of acute inflammation associated with respiratory disease. The product has also been known to have some benefit in the treatment of experimental acute bovine pulmonary emphysema (Fog Fever).
It may also be used as an adjunctive therapy in the treatment of acute mastitis.
Dosage and administration
Indicated for the intravenous administration to cattle and horses.
For use in musculo-skeletal disorders, the recommended dose is 1.1 ml flunixin/kg bodyweight, equivalent to 1 ml per 45 kg, once daily for up to 5 days depending on clinical response.
For use in equine colic, the recommended dose rate if 1.1 mg flunixin/kg bodyweight, equivalent to 1ml per 45kg. Treatment may be repeated once or twice if colic recurs.
For the treatment of endotoxaemia or shock-associated with gastric torsion and with other conditions in which the circulation of blood to the gastro-intestinal tract is compromised: 0.25 mg/kg (= 1 ml per 200 kg bodyweight) administered every 6-8 hours.
The recommended dose rate is 2.2mg flunixin/kg bodyweight, equivalent to 2ml per 45kg. Repeat as necessary at 24 hours intervals for up to 5 consecutive days. The cause of the acute inflammatory condition should be determined and treated with appropriate therapy.
Contra-indications, warnings, etc
Do not exceed the recommended dose or duration of treatment.
Do not administer to pregnant mares.
Intra-arterial injection should be avoided.
Do not mix Meflosyl 5% Injection with other medicaments prior to administration.
Do not use in animals showing hypersensitivity to flunixin meglumine.
Monitor drug compatibility closely when concurrent therapy is required.
Use in any animal less than 6 weeks of age, or in aged animals may involve additional risk. If such use cannot be avoided, animals may require a reduced dosage and careful clinical management.
Avoid use in hypovolaemic animals, except in the case of endotoxaemia or septic shock. It is preferable that NSAID's which inhibit prostaglandin synthesis are not administered to animals undergoing general anaesthesia until fully recovered. Non-steroidal anti-inflammatory drugs are not permitted under the Rules of Racing and under rules governing other competitive events. The Royal College of Veterinary Surgeons has given advice to the veterinary profession regarding the use of anti-inflammatory drugs in competing horses.
It states that "if a veterinarian recommends the discontinuation of any such drug not less than 8 days before racing, he should feel sure that he has catered for all but the most exceptional case!"
Do not use in animals suffering from cardiac, hepatic or renal disease where there is a possibility of gastro-intestinal ulceration or bleeding.
Horses: During treatment and within 7 days after the last injection, animals should not be slaughtered for human consumption.
Cattle: During treatment and within 7 days after the last injection, animals should not be slaughtered for human consumption.
Milk for human consumption must not be taken during treatment. Milk from treated cattle may be taken for human consumption, only after 36 hours from the last injection.
Avoid eye contact and direct contact with skin. To avoid possible sensitisation reactions, avoid contact with skin. Gloves should be worn during application. Wash hands after use. In case of accidental contact with eyes, rinse immediately with plenty of water and seek medical advice.
The product may cause reactions in sensitive individuals. If you have known hypersensitivity for non-steroidal anti-inflammatory products, do not handle the product. Reactions may be serious. Avoid accidental self-injection.
Following withdrawal of the first dose, use the product within 28 days. Discard unused material.
Do not store above 25°C. Protect from light.
Keep container in outer carton.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
When container is broached (opened) for the first time, using the in-use shelf-life which is specified on the package leaflet, the date on which any product remaining in the vial should be discarded should be worked out. This discard date should be written in the space provided.
Keep out of the sight and reach of children.
For animal treatment only.
Legal category: POM-V
50 ml and 100 ml vials. Not all pack sizes may be marketed.
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