Solution for injection.
Clear, colourless aqueous solution. Each ml contains 75µg Peforelin as active ingredient
For biotechnical use and intended for group or herd treatment.
• Induction of the oestrous cycle in sows after weaning ·
• Induction of oestrus in sexually mature gilts following therapy to inhibit the oestrus cycle with progestagens
Dosage in µg Peforelin and ml Maprelin per animal. The dosage is dependent on the parity.
Primiparous sows 24 hours after weaning off the piglets: 37.5 µg = 0.5 ml
Pluriparous sows 24 hours after weaning off the piglets: 150 µg = 2.0 ml
Gilts 48 hours after the termination of the
medication for the inhibition of the cycle: 150 µg = 2.0 ml
For intramuscular injection. For single application.
Use automatic syringe equipment for the 50 ml and 100 ml vials.
Do not use in prepubertal gilts, in case of infertility or general health disorders. Do not use in case of hypersensitivity to the active substance or to any of the excipients.
The safety of the product has not been established in sows and gilts during pregnancy and lactation. Laboratory studies in mice produced evidence of teratogenic effects. Do not use Maprelin in animals during pregnancy and lactation.
The product might induce irritation and sensitization. Persons with a known hypersensitivity to GnRH analogues or any of the excipients should not administer the product. Pregnant women should not administer the product, as an accidental self-injection by the user cannot be excluded and because GnRH analogues have been shown to be foetotoxic in laboratory animals. Women of childbearing age should administer the product with special caution.
In the case of accidental self-injection, seek medical advice and show the package leaflet to the doctor.
In case of accidental contact with the skin, the corresponding area should be thoroughly cleaned with soap and water, as GnRH analogues may be absorbed through the intact skin. In case of contact with the eyes, they should be thoroughly rinsed with water.
No adverse reactions were ascertained in pigs following treatment with up to three times the highest recommended dosage.
Interactions with other drugs
The simultaneous treatment of Maprelin with PMSG or hCG can possibly lead to an over-reaction of the ovaries. No interactions were reported following administration of the product 48 hours after the end of prior altrenogest therapy.
Meat and offal: zero days
For animal treatment only. Keep out of the reach and sight of children. Wash hands after use.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Store in a refrigerator (2 °C - 8 °C).
Protect from light. Keep the vial in the outer carton.
Shelf life after first opening the immediate packaging: 28 days.
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