Loxicom 5mg/ml Solution for Injection For Dogs and Cats

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Loxicom 5mg/ml Solution for Injection For Dogs and Cats


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Item Number: LOXICOMCD 
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10ml £43.69 Usually despatched within 24 hours
20ml £79.15 Usually despatched within 24 hours

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NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.
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You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

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 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post



Description

Loxicom 5mg/ml Solution for Injection For Dogs and Cats.

Presentation

Each ml contains:

Meloxicam 5 mg/ml
Sodium Benzoate 150 mg/ml

Uses

Dogs: Alleviation of inflammation and pain in both acute and chronic musculoskeletal disorders.
Reduction of post-operative pain and inflammation following orthopaedic and soft tissue surgery.

Cats: Reduction of post-operative pain after ovariohysterectomy and minor soft tissue surgery.
Dosage & Administration

Dosage and Administration for Dogs:

Musculo-skeletal disorders: Single subcutaneous injection at a dosage of 0.2 mg meloxicam/kg bodyweight (i.e. 0.4 ml/10 kg bodyweight). Loxicom 1.5 mg/ml oral suspension and Loxicom 0.5 mg/ml oral suspension may be used for continuation of treatment at a dosage of 0.1 mg meloxicam/kg bodyweight, 24 hours after administration of the injection.

Reduction of post-operative pain (over a period of 24 hours): Single intravenous or subcutaneous injection at a dosage of 0.2 mg meloxicam/kg bodyweight (i.e. 0.4 ml/10 kg bodyweight) before surgery, for example at the time of induction of anaesthesia.

Particular care should be taken with regard to the accuracy of dosing. Avoid the introduction of contamination during use.

Dosage and Administration for Cats:

Reduction of post-operative pain: Single subcutaneous injection at a dosage of 0.3 mg meloxicam/kg bodyweight (i.e. 0.06 ml/kg bodyweight) before surgery, for example at the time of induction of anaesthesia.

Particular care should be taken with regard to the accuracy of dosing. Avoid the introduction of contamination during use.

Contraindictions, Warnings etc

Do not use in pregnant or lactating animals. Do not use in animals suffering from gastrointestinal disorders such as irritation and haemorrhage, impaired hepatic, cardiac or renal function and haemorrhagic disorders. Do not use in case of hypersensitivity to the active substance or to any of the excipients. Do not use in animals less than 6 weeks of age nor in cats of less than 2 kg. Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of increased renal toxicity.

Typical adverse reactions of non-steroidal anti-inflammatory drugs NSAIDs such as loss of
appetite, vomiting, diarrhoea, faecal occult blood, apathy and renal failure have occasionally
been reported. In dogs, these adverse reactions occur generally within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal. In very rare cases anaphylactoid reactions may occur and should be treated symptomatically.
If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

For post-operative pain relief in cats, safety has only been documented after thiopental/halothane anaesthesia.

Other NSAIDs, diuretics, anticoagulants, aminoglycoside antibiotics and substances with high protein binding may compete for binding and thus lead to toxic effects. Loxicom must not be administered in conjunction with other NSAIDs or glucocorticosteroids. Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment free period with such drugs should be observed for at least 24 hours before commencement of treatment. The treatment-free period, however, should take into account the pharmacokinetic properties of the products used previously. Concurrent administration of potential nephrotoxic drugs should be avoided. In animals at anaesthetic risk (e.g. aged animals) intravenous or subcutaneous fluid therapy during anaesthesia should be taken into consideration. When anaesthesia and NSAID are concomitantly administered, a risk for renal function cannot be excluded.

In the case of overdose symptomatic treatment should be initiated
Pharmaceutical Precautions

This veterinary medicinal product does not require any special storage conditions.
Shelf-life after first opening the container: 28 days.
Do not use after the expiry date stated on the carton and the bottle.
Further Information

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, antiexudative and antipyretic effects. It reduces leukocyte infiltration into the inflamed tissue. To a minor extent it also inhibits collagen-induced thrombocyte aggregation. In vitro and in vivo studies demonstrated that meloxicam inhibits cyclooxygenase 2 (COX 2) to a greater extent than cyclooxygenase 1 (COX 1).

Following subcutaneous administration, meloxicam is completely bioavailable and maximal mean plasma concentrations of 0.73?g/ml in dogs and 1.1 ?g/ml in cats were reached approximately 2.5 hours and 1.5 hours postadministration, respectively.

There is a linear relationship between the dose administered and plasma concentration observed in the therapeutic dose range in dogs. More than 97% of meloxicam is bound to plasma proteins. The volume of distribution is 0.3 l/kg in dogs and 0.09 l/kg in cats. In dogs, meloxicam is predominantly found in plasma and is also a major biliary excretion product whereas urine contains only traces of the parent compound. Meloxicam is metabolised to an alcohol, an acid derivative
and to several polar metabolites. All major metabolites have been shown to be pharmacologically inactive. Meloxicam is eliminated with a half-life of 24 hours in dogs and 15 hours in cats. Approximately 75% of the administered dose is eliminated via faeces and the remainder via urine.

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

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Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

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