Louping-Ill Vaccine for Sheep 20ml.
For the active immunisation of sheep to stimulate an immunological response to the Louping III virus.
Onset of immunity is within 4 weeks of vaccination and duration as shown by an anamnestic response is at least 18 months.
Dosage and administration
Administer a 1 ml dose by subcutaneous injection on the side of the neck.
To facilitate injection, the vaccine should be removed to a warm room a few hours before use.
Pre-warming of the vaccine should not exceed 37 °C (blood temperature) for 30 minutes or 25 °C for 8 hours.
Shake the container well before withdrawing the doses.
Animals should be revaccinated after 2 years, at least 4 weeks prior to the period of greatest infection risk.
Contra-indications, warnings, etc
Occasional hypersensitivity reactions may occur. In such case, appropriate treatment such as adrenaline should be administered without delay.
Lambs born from vaccinated ewes acquire passive antibody, via the colostrum, for the first few weeks of life.
In any animal population there may be a small number of individuals which fail to respond fully to vaccination. Successful vaccination depends upon correct storage and administration of the vaccine and the ability of the animal to respond. This can be influenced by such factors as genetic constitution, intercurrent infection, age, nutritional status, concurrent drug therapy and stress.
The recommended injection site is on the side of the neck. Do not administer by intramuscular injection.
In view of the oily nature of the vaccine, very strict precautions against contamination should be taken since abscess formation may prevent satisfactory immunisation.
Syringes and needles should be sterilised before use and the injection should be made through an area of clean, dry skin.
A dry day should be selected for vaccination.
No information is available from laboratory studies on the safety of this vaccine administered during early to mid pregnancy, although experience of use in the field suggests that problems are unlikely to occur. Animals should not be vaccinated within the last month of gestation.
Local reactions at the injection site are anticipated in the majority of animals after vaccination due to the oil adjuvant in the vaccine. Non-painful dermal thickening and swelling may produce a local reaction of up to 5 x 10 cm approximately 2-3 weeks after vaccination. The reaction will persist but slowly resolve over a 4-5 week period. Some loss of wool may occur at the injection site. No information on microscopic features of the injection site reactions is available.
Note: These observations were noted after administration of a double dose (2 ml) of vaccine.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.
Do not mix with any other veterinary medicinal product.
To the user
This product contains mineral oil. Accidental injection/self injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.
If you are accidentally injected with this product, seek prompt medical advice even if only a very small amount is injected and take the package insert with you. If pain persists for more than 12 hours after medical examination, seek medical advice again.
To the doctor
This product contains mineral oil. Even if small amounts have been injected, accidental injection with this product can cause intense swelling, which may, for example, result in ischaemic necrosis and even the loss of a digit. Expert, PROMPT surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.
For animal treatment only. Keep out of reach and sight of children.
Store in a refrigerator (2 °C to 8 °C). Protect from light. Do not freeze.
After first opening the containers, the contents should be used immediately.
Any unused veterinary medicinal product or waste material derived from such products should be disposed of in accordance with local requirements.
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