Equip WNV Emulsion for injection for horses.
Emulsion for injection for horses.
Each dose of 1ml contains inactivated West Nile Virus, strain VM-2, RP* 1.0 - 2.2.
Squalane 1.61 mg
Pluronic L121 1.00mg
Polysorbate 80 0.172 mg
* Relative potency by in vitro method, compared to a reference vaccine that was shown efficacious in horses.
For the active immunisation of horses of 6 months of age or older against West Nile Virus (WNV) disease by reducing the number of viraemic horses after infection with WNV lineage 1 or 2 strains and to reduce duration and severity of clinical signs against WNV of lineage 2 strains.
Onset of immunity: 3 weeks after primary vaccination course.
Duration of immunity: 12 months after primary vaccination course for WNV lineage 1 strains. For WNV lineage 2 strains the duration of immunity has not been established.
Dosage and administration
For intramuscular use.
Administer one dose (1 ml), by deep intramuscular injection in the neck region, according to the following schedule:
· Primary vaccination course: first injection from 6 months of age, second injection 3-5 weeks later.
· Revaccination: a sufficient degree of protection should be achieved after an annual booster injection with a single dose although this schedule has not been fully validated.
Contra-indications, warnings, etc
Only healthy animals should be vaccinated.
Vaccination may interfere with existing sero-epidemiological surveys. However, since the IgM response following vaccination is infrequent, a positive IgM-ELISA test result is a strong indicator of natural infection with West Nile Virus. If infection is suspected as a result of a positive IgM response, additional testing would need to be conducted to conclusively determine whether the animal was infected or vaccinated. No specific studies have been conducted to demonstrate absence of interferences from maternally derived antibodies on vaccine take. It is therefore recommended not to vaccinate foals of less than 6 months of age.
A small number of animals may show transient local reactions in the form of a mild, local swelling at the injection site post vaccination (maximum 1 cm in diameter) that resolve spontaneously within 1 to 2 days. It is sometimes associated with pain and mild depression. In some cases hyperthermia may occur for up to 2 days.
Can be used during pregnancy and lactation.
No specific efficacy studies were conducted in pregnant mares. As a consequence, it cannot be excluded that transient immunodepression that may be observed during pregnancy could interfere with vaccine uptake.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Do not mix with any other veterinary medicinal product.
Withdrawal period: Zero days.
In case of accidental self-injection, ingestion or spillage onto skin, seek medical advice immediately and show the package leaflet or label to the physician.
Store and transport refrigerated (2 °C - 8 °C).
Do not freeze.
Protect from light.
For animal treatment only.
Keep out of the sight and reach of children.
Box of 5, 10, or 25 syringes.
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