Duphamox 150 mg/ml Suspension for Injection.
Duphamox is an off-white suspension for injection containing 150 mg of amoxicillin (as Amoxicillin Trihydrate) per ml. Each ml also contains Butylhydroxyanisole 0.08 mg and Butylhydroxytoluene 0.08 mg as antioxidants.
Duphamox is indicated in the treatment and control of infections caused by organisms sensitive to amoxicillin.
Amoxicillin is a broad-spectrum semi-synthetic penicillin bactericidal in action. In vitro it is effective against a wide range of Gram-positive and Gram-negative bacteria which include:
Actinomyces bovis, Actinobacillus equuli, Actinobacillus lignieresi, Bacillus anthracis, Bordetella bronchiseptica, Clostridium spp, Corynebacterium spp, Erysipelothrix rhusiopathiae, Escherichia coli, Fusiformis spp, Haemophilus spp, Moraxella spp, Pasteurella spp, Proteus mirabilis, Salmonella spp, Staphylococci and Streptococci (non-penicillinase producing) in cattle, sheep, pigs, dogs and cats.
Dosage and administration
Shake well before use.
Administration is by the intramuscular route for cattle, sheep and pigs and by the intramuscular or subcutaneous route in dogs and cats. The dosage rate is 7mg/kg bodyweight daily for up to 5 days (equivalent to 0.25ml per 5kg daily). Massage the injection site after injection.
The suggested dosage rates are
Normal aseptic precautions should be observed. Use a dry syringe for extraction of suspension to avoid hydrolysis of amoxicillin.
If dose volume exceeds 20 ml in cattle or 10 ml in sheep and pigs, it should be divided and injected into two sites.
A separate injection site should be used for each administration.
An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.
Contra-indications, warnings, etc
FOR ANIMAL TREATMENT ONLY
Do not use in cases of known hypersensitivity.
Not suitable for intravenous or intrathecal administration.
Not to be used in small herbivores such as rabbits, hamsters, gerbils and guinea pigs.
Not effective against beta-lactamase producing organisms.
Occasional local tissue reaction may result from the use of this product.
Milk for human consumption must not be taken from a cow during treatment. Milk for human consumption may only be taken from cows after 24 hours from the last treatment.
Not for use in sheep producing milk for human consumption.
Animals must not be slaughtered for human consumption during treatment.
Cattle may be slaughtered for human consumption only after 18 days from the last treatment.
Sheep may be slaughtered for human consumption only after 10 days from the last treatment.
Pigs may be slaughtered for human consumption only after 16 days from the last treatment.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
1.Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.
2.Handle this product with great care to avoid exposure, taking all recommended precautions.
3.If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention.
Wash hands after use.
Do not store above 25°C. Protect from light.
This product does not contain an antimicrobial preservative. Swab the septum before removing each dose. Use a dry, sterile needle and syringe.
Keep out of the reach and sight of children.
Following withdrawal of the first dose, use the product within 28 days. Discard unused material.
Multidose vials of 100 ml.
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