Coliplus 2,000,000 IU/ml Concentrate for Oral Solution 1L

Coliplus 2,000,000 IU/ml Concentrate for Oral Solution 1L


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Item Number: COLIPLUS 
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Unit Price:

£51.59 (Incl. Vat)

Usually despatched within 24 hours

Quantity

NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.
X

You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post



Description

Coliplus 2,000,000 IU/ml Concentrate for Oral Solution 1L.

Target species:
Cattle (calves), sheep (lambs), swine and chickens.

Indications for use:
Treatment of gastrointestinal infections caused by non-invasive Escherichia coli susceptible to colistin.

Contra-indications:
Do not use in case of hypersensitivity to polypeptide antibiotics or to any of the excipients.
Do not use in case of resistance to the polymyxin.

Special warnings for each target species:
Use of the product should be based on susceptibility testing and take into account official and local antimicrobials policies.

Special precautions for use:
Special precautions for use in animals
Using the veterinary medicinal product (antimicrobials) in poultry should be in accordance with Commission Regulation EC 1177/2006 and subsequent national requirements.
In the case of newborn animals and of animals with severe gastrointestinal and renal disorders the absorption of colistin may be increased. Neuro- and nephrotoxic alterations may occur.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:
People with known hypersensitivity to polymyxins should avoid contact with the veterinary medicinal product.
It is recommended to wear gloves when handling or administering the product.
Do not eat, drink or smoke while handling the product.
In case of accidental eye exposure, wash with plenty of water and seek medical advice immediately and show the label to the physician.
Wash hands after use

Adverse reactions:
None known.

Use during pregnancy, lactation or lay:
The safety of the veterinary medicinal product has not been established during pregnancy, lactation or lay in the target species. Use only accordingly to the risk/benefit of the veterinarian.
Using the veterinary medicinal product (antimicrobials) in poultry should be in accordance with Commission Regulation EC 1177/2006 and subsequent national requirements.
Interaction
After oral administration of colistin sulphate interaction with anaesthetics and myorelaxants may not be excluded in individual cases. The combination with aminoglycosides and levamisole should be avoided. The effects of colistin sulphate may be antagonized by binary cations (iron, calcium, magnesium) and by unsaturated fatty acids and polyphosphates.

Amounts to be administered and administration route:
Dosage:
To be administered orally:
For calves, lambs and pigs the recommended dose is 100 000 IU of colistin per kilogram body weight daily for 3-5 consecutive days. The recommended daily dose should be divided into two if the product is to be administered directly into the mouth of the animal.
For poultry the recommended dose is 75 000 IU of colistin per kilogram body weight daily for 3-5 consecutive days.
Administration via drinking water
The uptake of medicated water depends on the physiological and clinical conditions of the animals. In order to obtain the correct dosage, the concentration of colistin has to be adjusted accordingly. Carefully calculate the total body mass to be treated and the total daily water consumption before each treatment. Medicated water should be made every day, immediately prior to provision.
The medicated water should be the only source of drinking water for the animals for the entire duration of the treatment period.
With the following formula we can calculate an exact dosage:

With the following formula we can calculate an exact dosage:
...ml Coliplus per kg body weight & day
x
Average bodyweight (kg)
=
...ml Coliplus per litre of drinking water
______________________________________________________________________________
  
Average daily water intake (l/animal)
  
•Administration without a dosing pump:
The treatment is distributed in a tank over a period of 24 hours, for 3 consecutive days.
Coliplus is added to a volume of the drinking water corresponding to the volume consumed by the animals over the treatment period (24 hours) to achieve a dose of IU of colistin per kg body weight. The following sequential steps should be followed:
From the dosage regimen and the total weight of animals to be treated, determine the necessary quantity of active ingredient, and deduce the necessary quantity of commercial product.
Determine the mean water consumption of the animals to be treated over 24 hours.
The following formula can be applied:
1) Calculation of product solution volume at each day (V):
V (ml) = (Dosage per day in IU/kg b.w. x Total weight of animals to treat) / 2,000,000 IU.
2)Calculation of the quantity of drinking water to prepare (Qwater):
Qwater (L): (Mean individual water consumption/day) x (Number of animals to be treated)
•Administration via a dosing pump:
The treatment is distributed over a period of 24 hours, for 3 consecutive days.
A dosing pump is used to add a stock solution at a pre-determined concentration to the drinking water. The pumped volume is constant, but the drinking frequency depends on the flow rate of the circuit. The flow rate (F) through the pump is a percentage.
If the product is administered with an automated drinking water system, we have to calculate the volume and the concentration of the stock solution. The following sequential steps should be followed:
1.Calculation of product solution volume at each distribution (V): V (ml) = (Dosage per day in IU/kg b.w. x Total weight of animals to treat) / 2,000,000 IU
2.Calculation of the drinking water concentration (C): C (ml/L) = V / Total volume of water consumed by the animals in 24 hours.
3.Calculation of the stock solution volume (Vstock) Vstock (L) = Total volume of water consumed by the animals in 24 hours x F
4.Calculation of the stock solution concentration (Cstock):Cstock (ml/L) = C / F”

Overdose:
None.

Withdrawal periods:
Meat and offal: Calves, Lambs, Pig and Poultry: 1 day
Eggs: Zero days
Not permitted for use in animals producing milk for human consumption.

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

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Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
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