Clamoxyl Long Acting 150 mg/ml Suspension for Injection is an off-white oily suspension containing 150 mg/ml amoxicillin as Amoxicillin trihydrate.
The formulation is designed to provide effective antibiotic activity over a period of 48 hours.
Clamoxyl is a broad spectrum semi-synthetic penicillin which is bactericidal in vitro, against a wide range of Gram-positive and Gram-negative bacteria, including the following:
streptococci and staphylococci (penicillin sensitive strains)
Clamoxyl Long Acting Suspension for Injection is suitable for the control of infections caused by susceptible organisms in sheep, dogs and cats where prolonged activity from a single injection is required. It may also be used to control secondary bacterial invasion in conditions where bacteria are not a primary cause of disease.
Particular indications for Clamoxyl L.A. Injection are:
1.Alimentary tract infections, including enteritis.
2.Respiratory tract infections.
3.Urogenital tract infections, including cystitis and metritis.
4.Skin and soft tissue infections, including wounds, abscesses, foot infections, joint and navel ill.
5.Prevention of post-operative infections by injection prior to surgery.
Dosage and administration
The recommended dosage rate is 15 mg/kg bodyweight, which is equivalent to 1 ml/10 kg. If necessary, the dose may be repeated after 48 hours.
The following is intended as a guide
Animal Specimen weight (kg) Dose (volume) Sheep 65 6.5 ml Lamb 10 1.0 ml Dog – large 35 3.5 ml – medium 20 2.0 ml – small 10 1.0 ml Cat 5 0.5 ml
Dog – large
Shake the vial well before use. Inject by the subcutaneous or intramuscular route (dogs and cats) or the intramuscular route only (sheep), then massage the injection site. (For ease of administration in dogs and cats, needles no finer than 20 gauge should be used). If the volume to be given is greater than 5 ml (sheep) it should be divided and injected into two separate sites. The suspension is not suitable for intravenous or intrathecal administration.
In common with other penicillin preparations, hydrolysis takes place rapidly in the presence of water. It is important, therefore, that a dry syringe is used when extracting suspension for injection, to avoid contaminating the remaining contents of the vial with drops of water. Do not broach the vial more than 40 times.
Contra-indications, warnings, etc
Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on epidemiological information.
In common with all other penicillins, amoxicillin should not be used orally or parenterally in rabbits, guinea pigs, hamsters or gerbils. Caution is advised in its use in any other very small herbivores.
Use of the product may occasionally result in local tissue reaction.
Sheep meat: 45 days
Not for use in sheep producing milk for human consumption.
Care should be taken to avoid accidental self-injection.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.
Handle this product with great care to avoid exposure, taking all recommended precautions.
If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention.
Wash hands after use.
Do not store above 25°C.
This product does not contain an antimicrobial preservative. Following withdrawal of the first dose, use the product within 28 days. Discard unused material.
Any unused product or waste materials should be disposed of in accordance with local requirements.
Keep out of the reach of children.
For animal treatment only.
Clamoxyl Long Acting Suspension for Injection is available in packs containing 6 x 100 ml and 4 × 250 ml vials.
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