Celevac 500mg Tablets (pack of 112).This tablet is a bulking agent which is used to maintain the consistency of stools and can relieve symptoms of both diarrhoea and constipation.
Each tablet contains 500mg of methylcellulose.
Methylcellulose is a hydrophilic colloid which absorbs water causing it to swell to a soft gel of uniform consistency.
Recommended clinical use
- In the control of colostomy, ileostomy and simple diarrhoea
- In the management of diverticular disease and ulcerative colitis
- In the management of simple constipation
- As an aid to appetite control and the treatment of obesity
Route of administration Oral.
It is recommended that the tablets should be broken in the mouth before swallowing. Celevac tablets swell in contact with water and should therefore be swallowed carefully. It is not recommended that these tablets be taken before going to bed.
Colostomy and ileostomy control and for simple diarrhoea: 3-6 tablets twice daily with the minimum of liquid. Liquids should be avoided for 30 minutes before and after each dose. Dosage should be adjusted to give stools of the required consistency.
Diverticular disease and ulcerative colitis: 3-6 tablets twice daily adjusted according to the degree of constipation (with 300ml of liquid), diarrhoea (with a little liquid) or spastic pain.
Simple constipation: 3-6 tablets twice daily to be taken with at least 300 ml of liquid. The dose may be reduced as normal bowel function is restored.
As an aid to appetite control and the treatment of obesity: 3 tablets with at least 300 ml of warm liquid, half an hour before each meal and between meals when hunger pangs are severe.
Celevac tablets are contraindicated in patients:
- hypersensitive to methylcellulose or to any of the excipients
- with imminent or threatened intestinal obstruction
- with faecal impaction
- who have difficulty in swallowing
- with colonic atony
- with infective bowel disease
- with severe dehydration
Adequate fluid intake should be maintained to avoid intestinal obstruction. Guidance on fluid intake is stated in Section 4.2 Posology and method of administration.
Supervision may be necessary for patients who:
- are elderly
- are debilitated
- have intestinal narrowing
- have decreased intestinal motility
Bowel obstruction is a rare complication of treatment with any bulk-forming hydrophilic colloid (refer also to Section 4.8 Undesirable Effects).
Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
Although Celevac has been in wide general use for many years there is no evidence of ill consequence during human pregnancy. Medicines should not be used in pregnancy, especially the first trimester, unless the expected benefit is thought to outweigh any possible risk to the foetus.
Methylcellulose is not absorbed. The features to be expected would be abdominal distension which may be followed by intestinal obstruction.
Gastric lavage should be employed where appropriate. The patient should be observed and fluid given. If obstruction develops, appropriate measures such as rectal washout must be taken.
List of excipients
Strawberry flavour 52.318 AP
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