Bovilis Ringvac Vaccination for cattle.
Live vaccine containing > 7 x 106 and = 21 x 106 viable microconidia of Trichophyton verrucosum strain LTF-130 per ml after reconstitution in the solvent provided.
For active immunisation of cattle to reduce clinical signs of ringworm caused by Trichophyton verrucosum (prophylactic dose) and to shorten the recovery time of infected cattle showing clinical signs of ringworm (therapeutic dose).
Onset of immunity has been demonstrated at 3 weeks after completion of the recommended course.
The duration of protection has not been determined but experience of use in the field suggests that after the recommended course has been completed cattle continue to be protected without re-vaccination.
Dosage and administration
Calves from 2 weeks to 4 months: 2 ml
Calves from 2 weeks to 4 months: 4 ml
Older cattle : 4 ml
Older cattle : 8 ml
Administration is by intramuscular injection preferably in the neck.
Do not use chemicals, e.g. alcohol, for sterilisation.
The required dose is prepared by reconstituting the vaccine with the accompanying solvent.
Reconstitution of the 20-dose presentation
Reconstitute the vaccine immediately before use by transferring about 5 ml of diluent to the vaccine vial using a sterile needle and syringe. Agitate the vial to ensure that the lyophilisate is fully dissolved and syringe the entire contents into the diluent vial to mix with the remaining diluent.
Initially the whole herd should be vaccinated with a course of 2 vaccinations, 10-14 days apart. Subsequently, for closed herds only young calves require revaccination at around 2 weeks of age, followed by a second injection 10-14 days later. New animals introduced into the herd should receive a full vaccination course at the appropriate dosage. No subsequent doses are required.
Can be used during pregnancy.
Contra-indications, warnings, etc
Cattle already infected with, or in the incubation of infection with Trichophyton verrucosum, should not be vaccinated with the prophylactic dose. In such cases, animals show signs of the disease which could be severe.
Three to eight days after vaccination a local reaction may occur at the injection site, characterised by local swellings, hairless places or crust forming (up to 2 cm diameter) which, however, decrease after 3 weeks.
Only local reactions and slight temperature rise were observed after vaccination with 10 times the normal dose.
Occasional hypersensitivity reactions may occur. In such cases appropriate treatment with e.g. adrenaline should be given without delay.
Use fresh sterilised equipment for each injection.
No information is available on the safety and efficacy of this vaccine with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Do not mix with any other veterinary medicinal products except the solvent supplied for use with the vaccine.
Immuno-suppressed individuals should not use the product.
For animal treatment only. Keep out of reach and sight of children.
Store between +2°C and +8°C. Do not freeze. Protect from light.
Reconstituted vaccine should be used within the shortest time period necessary without exceeding a 4 hour period.
Dispose, of waste material by boiling, incineration or immersion in an appropriate disinfectant, in accordance with the national requirements.
1 x 5 calf doses and 1 x 10 ml solvent in glass bottles closed with a rubber stopper/aluminium combination cap.
1 x 20 calf doses and 1 x 40 ml solvent in glass bottles closed with a rubber stopper/aluminium combination cap.
For both presentations the vaccine is contained into 10 ml glass vials of PhEur Type I quality, while the solvent is contained into 10 ml (5-dose presentation) or 50 ml (20-dose presentation) glass vials of PhEur Type II quality. Both the vaccine and the solvent vials are closed with bromobutyl rubber stoppers of PhEur Type I quality.
Not all presentations may be marketed.
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