Bovilis IBR Marker inac, Suspension for injection
Qualitative and quantitative composition
Per dose of 2 ml.
Inactivated antigen of BHV-1(gE-) strain GK/D
60 ELisa units for induction of 6.1 - 11.1 log2VN-units* in mouse potency test
* virus neutralising units
Al3+(as Aluminium-phosphate and - hydroxide)
6.0 - 8.8 mg
0.03 - 0.05%
For a list of excipients, see section Pharmaceutical Particulars.
Suspension for injection
Indications for use
For active immunisation of cattle to reduce the intensity and duration of clinical signs (pyrexia) induced by an infection with BHV-1 as well as to reduce the replication and nasal excretion of the field virus.
Onset of immunity: 3 weeks after basic vaccination.
Duration of immunity: 6 months after basic vaccination.
Special warnings for each target species
Efficacy has not been demonstrated in the face of maternally derived antibodies.
Special precautions for use
Vaccinate only healthy animals.
In the case of accidental self-injection, seek medical advice immediately and show the package leaflet or label to the physician.
Occasionally a hypersensitivity reaction may occur. In such cases an appropriate symptomatic treatment should be administered. At the injection site a local reaction may occur.
Use during pregnancy, lactation or lay
Can be used during pregnancy and lactation.
No information is available on the safety and efficacy when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Amounts to be administered and administration route
Use sterile vaccination equipment. Before use, allow the vaccine to reach ambient temperature (15°C - 25°C). Shake well before use. Intramuscular injection, 2 ml per animal. All cattle can be vaccinated from an age of three months onwards.
Basic vaccination: Two inoculations with an interval of 4 weeks.
Re-vaccination (after basic vaccination with Bovilis IBR marker inac or with Bovilis IBR marker live): One inoculation every 6 months.
Administration of a double dose does not cause other effects than after a single dose.
Bovilis IBR marker inac is an inactivated adjuvanted vaccine for active immunisation of cattle against bovine herpesvirus type 1 (BHV-1). The vaccine does not elicit antibodies to glycoprotein E of BHV-1 (marker vaccine). This enables discrimination between cattle vaccinated with the product and cattle infected BHV-1 field virus.
Pharmacotherapeutic group: inactivated viral vaccine, ATCvet code: QI02AA03.
Formaldehyde, Culture medium, Trometamol, Sodium chloride and Water for injections.
Do not mix with any other veterinary medicinal product.
Shelf-life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf-life after first opening the immediate packaging: 8-10 hours.
Special precautions for storage
Store in a refrigerator (2°C to 8°C). Do not freeze.
Hydrolytical glass type I (PhEur) or polyethylene-terephthalate (PET) vials with 5, 10, 25, 50 or 100 doses closed with a halogenobutyl rubber stopper and sealed with a coded aluminium cap.
Presentations: Cardboard boxes with 1 or 10 vials. Not all pack sizes may be marketed.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
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