Bioestrovet 0.250mg/ml solution for injection 20ml POM

Bioestrovet 0.250mg/ml solution for injection 20ml POM

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Item Number: BIOESTRO 
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Unit Price:

£41.89 (Incl. Vat)

Usually despatched within 24-48 hours


NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” can only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.

You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at [email protected]

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post


Bioestrovet 0.250mg/ml solution for injection for Cattle 20ml .

Cattle (heifers, cows):
- Induction of luteolysis allowing resumption of oestrus and ovulation in cyclic females when used during dioestrus
- Synchronisation of oestrus (within 2 to 5 days) in groups of cyclic females treated simultaneously
- Treatment of suboestrus and uterine disorders related to a functioning or persistent corpus luteum (endometritis, pyometra)
- Treatment of ovarian luteal cysts
- Induction of abortion until day 150 of pregnancy
- Expulsion of mummified foetuses
- Induction of parturition

Dosage and administration
Administer by intramuscular injection observing basic aseptic precautions.
0.5 mg cloprostenol/animal corresponding to 2 ml product per animal.
In order to synchronise oestrus in cattle, it is recommended that the product is administered on two occasions with an 11 day interval between treatments.
Termination of abnormal pregnancy: between day 5 and 150 after insemination.
Induction of parturition: within 10 days before the expected date of parturition.
It is recommended that the vial is not broached more than 10 times and that the appropriate vial size is used for prevailing usage conditions. Otherwise, automatic syringe equipment, or a suitable draw-off needle, should be used for the 50 ml and 100 ml vials to avoid excessive puncturing of the stopper.

Contra-indications, warnings, etc
Do not administer to pregnant animals unless the objective is to terminate the pregnancy.
Do not use in animals with cardiovascular, gastro-intestinal or respiratory problems.
Do not administer to induce parturition in cattle with suspected dystocia due to mechanical obstruction or if problems are expected because of an abnormal position of the foetus.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not administer intravenously.
Special warnings for each target species
There is a refractory period of four to five days after ovulation when cattle are insensitive to the luteolytic effect of prostaglandins.

Special precautions for use

Special precautions for use in animals
In case of oestrus induction in cattle: from the 2nd day after injection, adequate heat detection is necessary.
For the termination of pregnancy, best results are obtained before day 100 of gestation. Results are less reliable between day 100 and 150 of gestation.
Induction of parturition and abortion may increase the risk of complications, retained placenta, foetal death and metritis.
To reduce the risk of anaerobic infections (e.g. swelling, crepitus), which might be related to the pharmacological properties of prostaglandins, care should be taken to avoid injection through contaminated areas of skin. Clean and disinfect injection sites thoroughly before administration.
All animals should receive adequate supervision after treatment.

Adverse reactions (frequency and seriousness)
Localised post-injection bacterial infections, which may become generalised, are occasionally reported.
When used in cattle for induction of parturition and dependent on the time of treatment relative to the date of conception, the incidence of retained placenta may be increased.
In very rare cases, anaphylactic-type reactions can be observed which might be life-threatening and require rapid medical care.

Use during pregnanacy and lactation
Do not administer to pregnant animals unless the objective is to terminate the pregnancy.
The product can be used safely during lactation.
Interaction with other medicinal products and other forms of interaction
Do not administer the product together with non-steroidal anti-inflammatory drugs since they inhibit endogenous prostaglandin synthesis.
The activity of other oxytocic agents can be increased after the administration of cloprostenol.

Overdose may be associated with uneasiness and diarrhoea. These effects are usually transient and will resolve without treatment.
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.

Pharmaceutical precautions
Shelf life after first opening the immediate packaging: 28 days
Keep the vial in the outer carton in order to protect from light.
This veterinary medicinal product does not require any special temperature storage conditions.

Packaging quantities
20ml Type 1 (colourless) glass vial closed with bromobutyl rubber stopper coated with a teflon film (PTFE) and sealed with a polypropylene flip-off cap.


Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

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