Benazecare flavour tablets

Benazecare flavour tablets

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Item Number: BENAZFLAV 
Phone orders quick webcode: Q1000056

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5mg (pack of 28) £21.89 Usually despatched within 24 hours
5mg Single Tablet £0.79 Usually despatched within 24 hours
20mg Single Tablet £1.64 Usually despatched within 24 hours
20mg (pack of 28) £45.89 Usually despatched within 24 hours

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NB This is a prescription only medicine
How do I buy Prescription medicines from you?

  1. Obtain a Prescription from your vet
  2. Place your order online or by phone
  3. Either fax email* or post your prescription to us.
  4. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs must be sent via tracked, signature delivery and do not qualify for free delivery.
  5. **Unless your vet has stated that the original must be sent to us.
  6. Choose your delivery method. Either Royal Mail Special Delivery which operates a next working day service, requiring a signature(Our recommended option). Or First class post which is free, but at your own risk, and is usually next working day but may take longer.
  7. Hyperdrug Pharmaceuticals Ltd, Middleton In Teesdale, Barnard Castle, County Durham, DL12 0NG.
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You are ordering items which require a prescription, Tampering with a prescription or attempting to obtain extra unauthorise supplies is a criminal offence and will have to be reported to the authorities. “Controlled Drugs” such as Epiphen or Tramadol can be only be dispensed ofter receipt of an original valid prescription sent by post. Controlled Drugs are sent via tracked, signature delivery.

  1. Place your order online or by phone
  2. Obtain a Prescription from your vet
  3. Either post the original, fax it to 01833 641032, or email it to us at sales@hyperdrug.co.uk.

 I have a prescription on file
 I am sending you a prescription by email
 I am sending you a prescription by fax
 I am sending you a prescription by post



Description

Benazecare Flavour 5mg Tablets

Presentation

Beef flavoured, beige, divisible oval tablets. Each tablet contains 5 mg benazepril hydrochloride.

Uses

Benazecare is indicated for the treatment of congestive heart failure in dogs and the treatment of chronic renal insufficiency in cats.

After oral administration, benazepril is rapidly absorbed from the gastrointestinal tract and hydrolysed into benazeprilat, a highly specific and potent inhibitor of angiotensin converting enzyme (ACE). Benazeprilat produces significant inhibition of plasma ACE activity for more than 24 hours after a single dose in both dogs and cats. Inhibition of ACE leads to a reduced conversion of inactive angiotensin I into angiotensin II and therefore reduction in the effects mediated by angiotensin II, including vasoconstriction of both arteries and veins, retention of sodium and water by the kidney and remodelling effects (including pathological cardiac hypertrophy and degenerative renal changes).

In dogs with heart failure, benazeprilat lowers the blood pressure and volume loading effect on the heart.

In cats with renal insufficiency, benazeprilat reduces the protein loss in urine and normalises the elevated glomerular capillary pressure and reduces systemic blood pressure. Reduction in glomerular hypertension retards the progression of kidney disease by inhibition of further damage to the kidneys. Benazepril has been shown to increase the appetite, quality of life and the survival time of cats particularly in advanced disease.

Benazeprilat is excreted equally by both biliary and urinary routes in dogs and primarily via the biliary route in cats and therefore no adjustment of the dose of Benazecare is necessary in the treatment of cases with renal insufficiency. Onset of clinical efficacy can be expected approximately 1 week after initiation of treatment with benazepril hydrochloride.

Dosage and administration

In both dogs and cats, Benazecare should be given orally once daily with or without food. The duration of treatment is unlimited.

Congestive Heart Failure in Dogs

The recommended dose is 0.25 mg benazepril hydrochloride/kg body weight, to be given orally once daily. The dose may be doubled, still administered once daily, if judged clinically necessary and advised by the veterinary surgeon. The dosing regime is as follows:

BENAZECARE 5mg

Weight of dog (kg)

Standard dose

Double dose

5-10

0.5 tablet/day

1 tablet/day

11-20

1 tablet/day

2 tablets/day

Benazepril may be given with digoxin, diuretics and anti-arrhythmic drugs as necessary.

Chronic renal insufficiency in cats

The recommended oral dose is 0.5 mg benazepril hydrochloride/kg body weight according to the following table:

Weight of cat (kg)

BENAZECARE 5mg

2.5 - 5

0.5 tablet/day

>5 - 10

1 tablet/day

Contra-indications, warnings, etc

For animal treatment only.

For oral use only.

Do not use in any dog that has evidence of cardiac output failure, for example, due to aortic stenosis. Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.

On rare occasions in dogs, transient signs of hypotension such as lethargy and ataxia may occur especially at the start of treatment.

In cats with chronic renal insufficiency, benazepril may increase plasma creatinine concentrations at the start of therapy. This effect is related to the therapeutic effect of the product in reducing blood pressure, and therefore is not necessarily a reason to stop therapy in the absence of other signs. As is routine in cases of chronic renal insufficiency, it is recommended to monitor plasma creatinine during therapy.

Benazepril reduced erythrocyte counts in normal cats at high doses, but this effect was not observed at the recommended dose during clinical trials in cats with chronic renal insufficiency. As is routine in cases of chronic renal insufficiency, it is recommended to monitor erythrocyte counts during therapy. Benazepril may increase food consumption and body weight in cats. Emesis, anorexia, dehydration and lethargy have been reported on rare occasions in this species.

As is routine in cases of chronic renal insufficiency, it is recommended to monitor plasma creatinine and urea during therapy. The efficacy and safety of benazepril has not been established in cats below 2.5 kg body weight.

Do not use in pregnant or nursing bitches or queens, or in bitches or queens intended for breeding. Studies in laboratory animals (rats) have shown embryotoxic effects of benazepril at non-maternotoxic doses (urinary tract abnormalities in the foetus). The safety of the product has not been assessed during breeding or in pregnant or lactating dogs and cats. Benazepril reduces ovary/oviduct weights in cats when administered daily at 10 mg/kg for 52 weeks.

Laboratory studies in rats and observations in humans have produced evidence of teratogenic effects.

In dogs with heart failure, benazepril has been given in combination with digoxin, diuretics and anti-arrhythmic drugs without demonstrable adverse interactions.

In healthy dogs overdose up to 200-fold was asymptomatic. In healthy cats overdose up to 10-fold was asymptomatic. Transient reversible hypotension may occur in cases of accidental overdose. Symptomatic treatment should consist of intravenous infusion of warm isotonic saline.

In man, the combination of ACE inhibitors and NSAIDs can lead to reduced anti-hypertensive efficacy or impaired renal function. The combination of benazepril and other anti-hypertensive agents (e.g. calcium channel blockers, b-blockers or diuretics), anaesthetics or sedatives may lead to additive hypotensive effects. Therefore concurrent use of NSAIDs or other medications with a hypotensive effect should be considered with care. Renal function and signs of hypotension (lethargy, weakness etc) should be monitored closely and treated as necessary.

Interactions with potassium preserving diuretics like spironolactone, triamterene or amiloride cannot be ruled out. It is recommended to monitor plasma potassium levels when using benazepril in combination with a potassium sparing diuretic as life threatening reactions are a possibility.

User warnings

Pregnant women should take special care to avoid accidental exposure because ACE inhibitors have been found to affect the unborn child during pregnancy in humans.

Wash hands after use.

In case of accidental ingestion by children, seek medical advice immediately and show this label to the doctor.

Pharmaceutical precautions

Keep out of the reach and sight of children.

Do not store above 25°C.

Store in a dry place.

Return any halved tablet to the blister pack and use within 2 days.

Keep the blister pack in the outer carton.

Do not use after the expiry date stated on the carton.

Disposal

Any unused products or waste materials should be disposed of in accordance with national requirements.

Legal category

POM-V

Packaging Quantities

Aluminium blister packs containing 14 tablets packed in a cardboard box with a package leaflet. Benazecare Flavour 5 mg tablets are supplied in packs of 14, 28, 56 or 140 tablets. Not all pack sizes may be marketed.

Further information

No evidence of renal toxicity to benazepril has been observed in dogs or cats during clinical trials. The biliary excretion of benazepril means there is little risk of bioaccumulation in dogs with impaired renal function.

Marketing authorisation number

Vm 10347/4021

Delivery

Free shipping from Hyperdrug

Value Weight Delivery Charge*  
Over £49.00 Any Weight FREE*
Under £49.00 Under 250g £2.49
Under £49.00 No weight limit £4.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited delivery options are available.

Estimated " Usually shipped in" information is shown against most products

 

Due to the large volume of parcels Royal Mail and Parcel Force handle over the Christmas period, we advise you give as much time as possible to receive your goods. Please ensure you order any essentials, such as prescription only medicines and diets, as soon as possible for UK delivery before Christmas. 
 
Last posting dates to expect goods before Christmas
Royal Mail - Wednesday 14th December
Parcel Force - Friday 16th December
Fast Track - Wednesday 21st December
 
Hyperdrug.co.uk website is open 24 hours a day, 7 days a week.
 
Office Opening hours 
Monday 19th - Friday 23rd - OPEN 8am - 5.30pm
Saturday 24th - Tuesday 27th - CLOSED
Wednesday 28th - Friday 30th - OPEN 8am - 5.30pm
Saturday 31st - Monday 2nd - CLOSED
Tuesday 3rd - Friday 6th - OPEN 8am - 5.30pm
Saturday 7th - OPEN 9am - 4pm

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Reviews

 feefoProduct Reviews


Benazecare flavour tablets POM 20mg (pack of 28)

Hold prescription on file and always ready to help


Benazecare flavour tablets POM 20mg (pack of 28)

Excellent