A white paste containing 18.7mg/g ivermectin.
Treatment of nematode or arthropod infections due to:
Strongylus vulgaris (adults and L4 stage larvae [arterial])
Strongylus edentatus (adults and L4 stage larvae [tissue])
Strongylus equinus (adults)
Small strongyles- adults and luminal L4 stage larvae (including benzimidazole resistant strains)
Parascaris equorum (luminal L5 larvae and adults)
Oxyuris equi (L4 stage larvae and adults)
Onchocerca spp (microfilariae)
Gasterophilus spp (oral and gastric stages)
Dosage and administration
One syringe division of paste per 100 kg body weight (based on a recommended dosage of 200 microgram ivermectin per kg body weight). The total contents of a syringe (six divisions) will dose one 700 kg horse.
The paste is given by oral route.
Advice on correct administration
The weight of the horse should be accurately determined for the correct use of the paste. The animal’s mouth should be free from food to ensure swallowing. Turn the screw gauge on the syringe plunger to the body weight of the horse.
The tip of the syringe barrel should be inserted at the interdental space (the gap between the front and back teeth) and the paste deposited on the base of the tongue. Advance the plunger as far as it will go, depositing the medication on the base of the tongue. Immediately elevate the horse’s head for a few seconds to ensure swallowing.
Contra-indications, warnings, etc
Do not use in horses with known hypersensitivity to the active substance.
Do not use in dogs or cats as severe adverse reactions may occur.
Meat and offal: 34 days. Do not use in mares producing milk for human consumption.
Special precautions for use in animals
Some horses with heavy infections of Onchocerca spp. microfilariae have experienced oedema and pruritus following treatment. Such reactions are assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.
Anthelmintic use that might lead to an increased risk of development of resistance to anthelmintic drugs includes:
• Too frequent and repeated use of anthelmintics from the same class over an extended period of time, and
Veterinary advice should be given on appropriate dosing programs and stock management to achieve adequate parasite control and reduce the likelihood of anthelmintic resistance developing. In the event that a product is suspected of being ineffective, the animal owner is advised to seek veterinary advice.
The product has been formulated for use in horses only. Cats, dogs, especially Collies, Old English Sheepdogs and related breeds or crosses, and also in turtles and tortoises may be adversely affected by the concentration of Ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.
The product can be administered to mares at any stages of pregnancy or lactation.
Mild transitory signs (slowed pupillary light response and depression) have been seen at a higher dose of 1.8 mg/kg (9 times the recommended dose level). Other signs seen at higher doses include mydriasis (dilation of the pupil), ataxia (inco-ordination), tremors (shaking), stupor (dull), coma and death. The less severe signs have been transitory.
Although no antidote has been identified, symptomatic therapy may be beneficial.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Do not smoke, eat or drink while handling the product.
Wash hands after use.
This product may cause skin and eye irritation. Therefore, the user should avoid contact of the product with the skin and the eyes. In case of contact, rinse immediately with plenty of water.
In the case of accidental ingestion or eye irritation after contact seek medical advice immediately and show the package insert or the label to the physician.
Do not store above 25°C.
Special precautions for the disposal of unused product or waste material
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used container. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with national requirements.
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