Animec 0.8mg/ml Oral Solution for Sheep.
For the treatment of infections with the following parasites:
Gastrointestinal roundworms (adult and fourth larval stage): Haemonchus contortus, Teladorsagia circumcincta, Trichostrongylus spp., Cooperia spp., Nematodirus spp. including N. battus, Strongyloides papillosus, Chabertia ovina
Lungworms(adult and fourth larval stage): Dictyocaulus filaria
Nasal bot (all larval stages): Oestrus ovis
Dosage and administration
The veterinary medicinal product should be given orally. The recommended dose rate is 0.2 mg ivermectin per kg bodyweight (corresponding to 2.5 ml per 10 kg bodyweight).
Over 60 kg give 2.5 ml per 10 kg bodyweight
To ensure administration of a correct dose, body weight should be determined as accurately as possible. Accuracy of the dosing device should be checked.
If animals are to be treated collectively rather than individually they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or over- dosing.
Contra-indications, warnings, etc
Do not use in animals with known hypersensitivity to the active ingredient or any of the excipients.
Special precautions for use in animals
The timing of treatment should be based on epidemiological factors and should be customised for each individual farm. A dosing programme should be established by the veterinary surgeon.
Veterinary advice should be sought on appropriate dosing programmes and stock management to achieve adequate parasite control, and to reduce the likelihood of anthelmintic resistance developing. Veterinary advice should also be sought if the product does not achieve the desired clinical effect, as other diseases, nutritional disturbances or anthelmintic resistance might be involved.
Avermectins may not be well tolerated in non-target species. Cases of intolerance resulting in fatalities have been reported in dogs, especially Collies, Old English Sheep Dogs and related breeds or crosses, and also in turtles/tortoises.
Some sheep may cough immediately after treatment. This passing response is of no consequence.
If you notice any serious effects or other effects not mentioned in this label, please inform your veterinary surgeon.
Wash hands after use. Avoid contact with skin and eyes. Do not eat, drink or smoke while handling the product. Wear impervious gloves when handling or administering the product. As absorption through skin can occur, in the event of accidental skin contact, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water.
Use during pregnancy, lactation or lay
The veterinary medicinal product can be administered to ewes at any stage of pregnancy or lactation.
Overdose (symptoms, emergency procedures, antidotes), if necessary
At doses up to 4 mg ivermectin per kg administered by stomach tube (20x the recommended dose level) undesirable toxic reactions occurred. Acute symptoms (ataxia, staggering gait, incoordination, depression) were observed at the dose rate of 8 mg/kg (40x the recommended dose level) during a study carried out on 4 animals. Twenty-four hours later, the animals showed only mild incoordination and depression.
Three days post dose all the animals were nearly normal. It is possible that the signs of toxaemia were due to the propylene glycol.
No antidote has been identified. Symptomatic treatment may be beneficial.
Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing, which may be due to underestimation of body weight or misadministration of the product.
Resistance to ivermectin (an avermectin) has been reported in Teladorsagia in sheep and goats within the EU and it is common in Haemonchus in sheep outside the EU. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematode and recommendations on how to limit further selection for resistance to anthelmintics.
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, and anthelmintic belonging to another pharmacological class and having different mode of action should be used.
There is cross-resistance with other avermectins and with milbemycins.
Meat & Offal : 10 days. Milk: Do not use in lactating sheep producing milk for human consumption. Sheep must not be treated within 60 days prior to the commencement of lactation, if milk is to be used for human consumption.
Do not store above 30°C.
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used container. Any unused product or waste material should be disposed of in accordance with national requirements.
Legal category: POM-VPS
Flexi pack: 1, 2.5 , 5L and 6L (5L+1L)
Jerri-cans: 1, 2.5, 5L and 10 Litre
Not all pack sizes may be marketed.
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