Trimacare Bolus (pack of 20)-Hyperdrug

Presentation Scored white bolus-shaped antibacterial tablets. Each bolus contains: Trimethoprim Ph.Eur. 200 mg Sulfadiazine Ph.Eur. 1.0 g Uses Trimacare Boluses are primarily indicated for oral use in calves for the treatment of bacterial scours but may also be used for treatment of acute salmonellosis and bacterial pneumonia. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria giving a level of activity many times greater than that obtained from either drug alone. In vitro Trimacare Bolus is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella spp., Pasteurella spp., Salmonella spp. and Staphylococcus spp. The boluses are particularly effective against Escherichia coli and Salmonella spp. infections. Dosage and administration CALVES: The daily dose is one bolus per 40 kg (90lb) bodyweight given orally, providing 30mg of combined active constituents per kg bodyweight daily. Treatment should be repeated daily until two days after the symptoms have resolved, but in cases of salmonellosis and bacterial pneumonia, treatment should be continued for five consecutive days. Treatment must not be continued for more than five days. Trimacare Boluses may be administered whole, by hand or by balling gun, or dispersed in water. Dosage by dispersion in water: Disperse each bolus by shaking in about 300 ml of water in a dosing bottle. This may be facilitated by crushing the bolus before placing it in the bottle. After dosing by this method any unused material should be discarded. Contra-indications, warnings, etc Animals must not be slaughtered for human consumption during treatment. Calves may be slaughtered for human consumption only after 15 days from the last treatment. Trimacare Bolus should not be used in animals with a functionally mature rumen. Protective gloves should be worn to avoid skin sensitisation, which may occur when crushing the bolus of this product. Wash hands after use. Pharmaceutical precautions Do not store above 25°C. Store in a dry place Protect from light. Keep out of the reach of children Legal category POM-V (previously POM). Packaging Quantities Plastic tubs containing 20 boluses Further information Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority. Marketing authorisation number 2000/4148.

Dosage and administration CALVES: The daily dose is one bolus per 40 kg (90lb) bodyweight given orally, providing 30mg of combined active constituents per kg bodyweight daily. Treatment should be repeated daily until two days after the symptoms have resolved, but in cases of salmonellosis and bacterial pneumonia, treatment should be continued for five consecutive days. Treatment must not be continued for more than five days. Trimacare Boluses may be administered whole, by hand or by balling gun, or dispersed in water. Dosage by dispersion in water: Disperse each bolus by shaking in about 300 ml of water in a dosing bottle. This may be facilitated by crushing the bolus before placing it in the bottle. After dosing by this method any unused material should be discarded.

Contra-indications, warnings, etc Animals must not be slaughtered for human consumption during treatment. Calves may be slaughtered for human consumption only after 15 days from the last treatment. Trimacare Bolus should not be used in animals with a functionally mature rumen. Protective gloves should be worn to avoid skin sensitisation, which may occur when crushing the bolus of this product. Wash hands after use. Pharmaceutical precautions Do not store above 25°C. Store in a dry place Protect from light. Keep out of the reach of children