Presentation
Scored white bolus-shaped antibacterial tablets. Each bolus contains:
Trimethoprim Ph.Eur. 200 mg
Sulfadiazine Ph.Eur. 1.0 g
Uses
Trimacare Boluses are primarily indicated for oral use in calves for the treatment of bacterial scours but may also be used for treatment of acute salmonellosis and bacterial pneumonia. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria giving a level of activity many times greater than that obtained from either drug alone. In vitro Trimacare Bolus is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella spp., Pasteurella spp., Salmonella spp. and Staphylococcus spp.
The boluses are particularly effective against Escherichia coli and Salmonella spp. infections.
Dosage and administration
CALVES: The daily dose is one bolus per 40 kg (90lb) bodyweight given orally, providing 30mg of combined active constituents per kg bodyweight daily.
Treatment should be repeated daily until two days after the symptoms have resolved, but in cases of salmonellosis and bacterial pneumonia, treatment should be continued for five consecutive days. Treatment must not be continued for more than five days.
Trimacare Boluses may be administered whole, by hand or by balling gun, or dispersed in water.
Dosage by dispersion in water: Disperse each bolus by shaking in about 300 ml of water in a dosing bottle. This may be facilitated by crushing the bolus before placing it in the bottle. After dosing by this method any unused material should be discarded.
Contra-indications, warnings, etc
Animals must not be slaughtered for human consumption during treatment. Calves may be slaughtered for human consumption only after 15 days from the last treatment.
Trimacare Bolus should not be used in animals with a functionally mature rumen.
Protective gloves should be worn to avoid skin sensitisation, which may occur when crushing the bolus of this product.
Wash hands after use.
Pharmaceutical precautions
Do not store above 25°C. Store in a dry place
Protect from light.
Keep out of the reach of children
Legal category
POM-V (previously POM).
Packaging Quantities
Plastic tubs containing 20 boluses
Further information
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Marketing authorisation number
2000/4148.
Presentation
White circular uncoated antibacterial tablets scored on one side. Each tablet contains:
Uses
Trimacare 80 Tablets are indicated for oral use in dogs. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria resulting in a level of activity much greater than that obtained from either drug alone. In vitro, Trimacare is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Pasteurella multocida, Streptococcus spp., Staphylococcus spp., Salmonella spp., Corynebacterium spp., Proteus mirabilis and Citrobacter freundii.
When susceptible organisms are present Trimacare 80 Tablets may be effective in treating the following conditions: alimentary tract infections; respiratory and urogenital infections; skin and wound infections; eye and ear infections.
Dosage and administration
This product should be administered orally by hand.
Contra-indications, warnings, etc
This dosage form is not suitable for use in cats. Trimacare 20 Tablets should be administered to this species.
A low incidence of polyarthropathy and Keratoconjunctivitis Sicca (Dry Eye) has been reported in dogs following oral administration of potentiated sulphonamides. If either of these conditions occur, it is recommended that medication is stopped and that future treatment with similar products is avoided.
Sulphonamide sensitivity is rare in companion animals but should be considered in cases of unexpected responses to treatment.
Wash hands after use.
Pharmaceutical precautions
Store in a dry place. Do not store above 25°C.
Protect from light.
Keep out of reach of children.
Legal category
POM-V (previously POM)
Packaging Quantities
Plastic containers of 500 tablets.
Disposal
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Further information
This product may be used to continue treatment with Trimacare 24%.
Marketing authorisation number
VM 2000/4147.