White, biconvex, branded, scored tablets for oral administration. Each tablet contains: Trimethoprim Ph.Eur 80 mg; Sulphadiazine Ph.Eur 400 mg.
Principal action: The two active ingredients produce a sequential double blockade of bacterial synthesis of folinic acid, giving a level of activity many times greater than that obtained from either drug alone. The in vitro activity covers most common Gram-positive and Gram-negative bacteria including: Bordetella spp., Corynebacterium spp., Escherichia coli, Fusobacterium necrophorum, Haemophilus spp., Klebsiella spp., Listeria monocytogenes, Nocardia spp., Pasteurella spp., Proteus spp., Salmonella spp., Staphylococcus spp., and Streptococcus spp.
For use in dogs for the treatment of: alimentary tract infections, respiratory tract infections, urogenital tract infections, skin infections, general infections, infections of the ear and eye, also wounds. It may also be used for antibacterial medication in surgical cases where infection is likely to be present, e.g. with compound fractures and where there is established peritonitis.
Dosage and administration
The average daily dose is 30 mg (of combined active constituents) per kg bodyweight. This is achieved by giving one tablet per 32 kg bodyweight twice daily or one tablet per 16 kg bodyweight once daily.
Treatment should be continued until two days after symptoms have subsided, up to a maximum of 5 days.
Contra-indications, warnings, etc
Do not administer these tablets to cats. Do not administer to animals with known sulphonamide sensitivity, severe liver parenchymal damage and blood dyscrasias.
Do not administer in cases of severe renal impairment unless the dosage is reduced, adequate renal output is maintained and close veterinary supervision is available.
Sulphonamide sensitivity is rare in companion animals but should be considered in cases of unexpected responses to treatment.
There has been a low incidence of polyarthritis occurring mainly in larger breeds of dog.
Keep out of reach of children.
Dispose of any unused product in accordance with guidance from your local waste regulation authority.
Do not store above 25°C. Protect from light.
POM-V (previously POM)
Containers of 500 tablets.
This product may be used to continue treatment begun with Tribrissen Injection 24%.