Porcilis Coli Clos Suspension for injection for pigs 50ml, 25 Dose.
Qualitative and quantitative composition
Each dose of 2 ml contains:
Active substances:
| Escherichia coli components: | ||
| - F4ab fimbrial adhesin | = | 9.7 log2 Ab titre1 |
| - F4ac fimbrial adhesin | = | 7.8 log2 Ab titre1 |
| - F5 fimbrial adhesin | = | 7.4 log2 Ab titre1 |
| - F6 fimbrial adhesin | = | 7.6 log2 Ab titre1 |
| - LT toxoid | = | 12.0 log2 Ab titre 1 |
| Clostridium perfringens component: | ||
| - Type C (strain 578) beta toxoid | = | 20 IU2 |
1 Mean antibody titre (Ab) obtained after vaccination of mice with a 1/20 or 1/20 sow dose
2 International units of beta antitoxin according to Ph.Eur.
Adjuvant:
dl-alpha-tocopheryl acetate 150 mg.
For full list of excipients, see section "Pharmaceutical Particulars".
Pharmaceutical form
Suspension for injection. Aqueous, white to nearly white.
Clinical particulars
Target species
Pigs (sows and gilts).
Indications for use
For the passive immunisation of progeny by active immunisation of sows and gilts to reduce mortality and clinical signs during the first days of life, caused by those E. coli strains, which express the adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6 (987P) and caused by C. perfringens type C.
Contra-indications
None.
Special warnings for each target species
None.
Special precautions for use
Special precautions for use in animals
Vaccinate only healthy animals. Protection of piglets is achieved by colostrum intake. Therefore, care should be taken to ensure that each piglet ingests a sufficient quantity of colostrum.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Adverse reactions
An increase in body temperature up to 2°C may be observed on the day of vaccination. Reduced activity and lack of appetite on the day of vaccination commonly occurs and/or a sometimes painful and hard swelling up to 10 cm diameter for up to 25 days may be observed at the site of injection.
Use during pregnancy, lactation or lay
Can be used during pregnancy.
Interactions
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Amounts to be administered and administration route
Intramuscular injection of 1 dose (2 ml) of vaccine per animal in the neck in the area behind the ear.
Vaccination scheme:
Primary vaccination: Sows/gilts which have not yet been vaccinated with the product are given a primary injection 6 to 8 weeks before the expected date of farrowing and a second injection 4 weeks later.
Revaccination: A single revaccination is carried out 2 to 4 weeks before the expected date of farrowing.
Before use allow the vaccine to reach room temperature. Shake vigorously before use and at intervals during use.
Overdose
A slight redness and/or roughness may transiently occur after a double dose vaccination. No adverse reactions other than those mentioned in section "Adverse reactions" have been observed.
Withdrawal periods
Zero days.
Pharmacological particulars
Immunological properties
Pharmacotherapeutic group: inactivated bacterial vaccine. ATC vet code: QI09AB08.
To stimulate active immunity in order to provide passive immunity to the progeny against enterotoxicosis caused by E. coli expressing fimbrial adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99), F6 (987P) and against (necrotic) enteritis caused by C. perfringens type C. Vaccination results in an antibody response with neutralizing activity against LT toxin.
Pharmaceutical particulars
Excipients
Sodium chloride, Potassium chloride, Disodium hydrogen phosphate, Potassium dihydrogenphosphate, Simethicone, Polysorbate 80 and Water for injections.
Major incompatibilities
Do not mix with any other veterinary medicinal product.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening the vial: 10 hours.
Special precautions for storage
Store in a refrigerator (between +2°C and + 8°C). Protect from light. Do not freeze.
Immediate packaging
Cardboard box with PET vial of 20 ml, 50 ml, 100 ml, 200 ml or 250 ml.
Cardboard box with type I glass vial of 20 ml, 50 ml, 100 ml or 250 ml.
The vials are closed with a halogenobutyl rubber stopper and sealed with an aluminium cap.
Not all pack sizes may be marketed.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
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Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a valid signed and dated prescription.
Pick up
We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
