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Dosage Admin:
Cattle
Noromectin Multi Injection should be given only by subcutaneous injection at the recommended dosage level of 200 ug ivermectin per kilogram bodyweight. Each ml contains 10 mg of ivermectin sufficient to treat 50 kg of bodyweight. Use the following dosage schedule.
Bodyweight (kg) Dose Volume (ml)
Up to 50 1.0
51 to 100 2.0
101 to 150 3.0
151 to 200 4.0
201 to 250 5.0
251 to 300 6.0
301 to 350 7.0
351 to 400 8.0
401 to 450 9.0
451 to 500 10.0
501 to 550 11.0
551 to 600 12.0
Noromectin Multi Injection is to be given subcutaneously only. Inject under the loose skin in front of or behind the shoulder. Use of a 17 gauge x ½ inch (15-20 mm) needle is suggested. Replace with a fresh sterile needle after every 10-12 animals. Injection of animals with wet or dirty hides is not recommended.
Sheep
Noromectin Multi Injection should be given only by subcutaneous injection at the recommended dosage level of 200 g ivermectin per kilogram bodyweight (0.5 ml per 25 kg bodyweight). Each ml contains 10 mg ivermectin to treat 50 kg bodyweight.
Noromectin Multi Injection is to be given subcutaneously only. Inject once under the loose skin in the neck. For the treatment and control of sheep scab (Psoroptes ovis) two injections with a seven day interval are required to treat clinical signs of scab and eliminate living mites. Use of a 17 gauge x ½ inch (15-20 mm) needle is suggested. Replace with a fresh sterile needle after every 10-12 animals. Injection of wet or dirty animals is not recommended.
When treating sheep of less than 16 kg seek veterinary advice regarding the use of 1 ml disposable syringes graduated in increments of 0.1 ml.
For the treatment of individual sheep a syringe not exceeding 2.0 ml and calibrated in increments of 0.1 ml should be used.
Use the following dosage schedule:
Bodyweight (kg) Dose Volume (ml)
Up to 5 0.1
5.1 to 10 0.2
10.1 to 15 0.3
15.1 to 25 0.5
25.1 to 50 1.0
50.1 to 75 1.5
75.1 to 100 2.0
Pigs
Noromectin Multi Injection should be given only by subcutaneous injection in the neck at the recommended dosage level of 300 ug ivermectin per kilogram bodyweight (1 ml per 33 kg bodyweight).
Use the following dosage schedule. In young pigs, especially those weighing under 16 kg for which less than 0.5 ml of Noromectin is indicated, dosing accuracy is important. The use of a syringe that can accurately deliver 0.1 ml is recommended. For piglets weighing less than 16 kg the product should be given at 0.1 ml per 3 kg.
Bodyweight (kg) Dose Volume (ml)
17 to 33 1.0
34 to 50 1.5
51 to 66 2.0
67 to 99 3.0
100 to 133 4.0
134 to 166 5.0
167 to 200 6.0
Over 200 kg bodyweight give 1.0 ml per 33 kg bodyweight.
MODE OF ACTION
Ivermectin paralyses and ultimately kills parasitic nematodes, arachnids and insects by its effect on the nervous system of these parasites. At therapeutic doses, ivermectin has no adverse effect on cattle since it does not readily penetrate their central nervous systems. Ivermectin belongs to the avermectin class of anthelmintic endectocides.
WHEN TO USE NOROMECTIN MULTI INJECTION
The suggested dosing programme has been developed to make the best use of the properties of Noromectin Multi Injection. Your veterinary surgeon will be able to provide further advice.
Cattle
Stomach and Gut Roundworms
Roundworm larvae may survive on the pasture over the winter in great numbers. They infect grazing cattle immediately after turnout, maturing into egg laying worms and causing increased pasture contamination. Early season treatment with Noromectin Multi Injection keeps down the population of worms in your stock and reduces the number of worm eggs passed onto the pasture to cause later infection.
Where young cattle are set-stocked, treatments with Noromectin Multi Injection 3, 8 and 13 weeks after an April/May turnout will give season long control of parasitic gastro-enteritis and parasitic bronchitis.
Where clean pasture will be available during the summer, give a summer treatment with Noromectin Multi Injection and move stock to the clean pasture within two weeks of treatment. If stock are introduced to pasture contaminated by cattle grazing earlier in the year, it is advisable to continue treating with Noromectin Multi Injection at regular 5-6 weekly intervals to prevent the build up of worm parasites.
Ostertagia larvae picked up from the pasture in late summer and early autumn can remain dormant in the stomach wall for many months. In late winter or spring they resume development, resulting in serious disease. Autumn treatment with Noromectin Multi Injection kills these larvae, and prevents Type II ostertagiasis.
Lungworm
Outbreaks of husk (hoose) are most common in summer and autumn. Routine treatment with Noromectin Multi Injection for stomach and gut roundworm control, e.g. at 3 weeks, 8 weeks, and 13 weeks after turnout can be used to control lungworm infection.
Where outbreaks of husk occur, treat promptly with Noromectin Multi Injection and move stock to clean pasture within 2 weeks of treatment. However, note that lungworm larvae can survive in soil for up to a year or more, and it may be difficult to ensure that the pasture is 'clean'. If clean pastures are unavailable, treatments at 6 weekly intervals should control lungworm until housing.
Eyeworms
The presence of these worms may produce irritation and excessive tear formation in the eye. These tears attract flies which are responsible for the transmission of infection to other cattle. The eyeworms are present throughout the year but transmission from one animal to another, and the annoyance caused by the flies, occurs only during the summer months.
Treatment with Noromectin Multi Injection controls adult eyeworms in cattle at any time of the year.
Lice and Mites
Autumn treatment with Noromectin Multi Injection controls sucking lice, sarcoptic and psoroptic mange mites as infections start to build up. Noromectin Multi Injection may also be used as an aid in the control of biting lice and chorioptic mange mites, but complete elimination may not occur. Treat all animals in contact with each other to prevent cross-infection.
Warbles
The best time to treat is in autumn or early winter, when Noromectin Multi Injection stops the small migrating larvae before they have time to cause serious damage. Treatment with Noromectin Multi Injection kills all stages of warble larvae and may be given whenever convenient for the farmer.
In spring, warbles show as lumps on the backs of previously untreated cattle. Treatment with Noromectin Multi Injection kills these larvae, thus further reducing the population of adult flies for next season.
Pigs
Breeding Animals
At the time of initiating any parasite control programme, it is important to treat all breeding animals in the herd. After the initial treatment use Noromectin Multi Injection regularly as follows:
Sows
Treat preferably 7-14 days prior to farrowing, to minimise infection of piglets.
Gilts
Treat 7-14 days prior to service.
Treat 7-14 days prior to farrowing.
Boars
Treat at least twice per year.
The above programme is a guide for effective parasite control using Noromectin Multi Injection. Alternatively a wide measure of control may be achieved by "total herd treatment" at six-monthly intervals.
Fatteners
All pigs received for fattening should be treated before placement in clean quarters.
Note 1
For effective mange control, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities.
Note 2
Since louse eggs are unaffected by ivermectin and may take up to 3 weeks to hatch, complete elimination may not occur following a single injection.
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