Noromectin Injection 300ml | Cattle, sheep & pig wormer-Hyperdrug

Very useful product for worming cattle, sheep and pigs. Controlling lice and warbles in cattle, Sheep scab and lice and mange in pigs.

DOSAGE cattle 1ml per 50kg bodyweight

SHEEP 0.5ml/25kg

PIGS 1ml per 33kg

WITHDRAWAL PERIODS
CATTLE meat 35 days milk: do not use in cattle producing milk for human consumption
SHEEP meat; 42 days do not use on lactating sheep producing milk for human consumption
PIGS meat; 28 days

Presentation:

One low-volume dose of Noromectin Multi Injection controls internal and external parasites that impair the health and productivity.

Noromectin Multi Injection is a ready-to-use, sterile, non-aqueous solution of ivermectin. Ivermectin is derived from the avermectins, a family of highly active, broad-spectrum antiparasitic agents which are isolated from fermentation of the soil organism Streptomyces avermitilis.

Noromectin Multi Injection is a 1.0% w/v sterile solution of ivermectin. At the rate of 1 ml per 50 kg bodyweight by subcutaneous injection, this formulation will deliver the recommended dosage level of 200 ?g ivermectin per kg bodyweight to cattle and/or sheep. At the rate of 1 ml per 33 kg bodyweight by subcutaneous injection, this formulation will deliver the recommended dosage level of 300 µg ivermectin per kg bodyweight to pigs.

Product Uses:

Cattle
Noromectin Multi Injection is indicated for the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and sucking lice.

Gastrointestinal roundworms (adult and fourth stage larvae):
Ostertagia ostertagi (including inhibited larval stages), Ostertagia lyrata, Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia oncophora, Cooperia punctata, Cooperia pectinata, Bunostomum phlebotomum, Oesophagostomum radiatum, Strongyloides papillosus (adult), Nematodirus helvetianus (adult), Nematodirus spathiger (adult), and Trichuris spp (adult)

Lungworms (adult and fourth stage larvae): Dictyocaulus viviparus

Eyeworms (adult): Thelazia spp

Warbles: Hypoderma bovis and Hypoderma lineatum

Mange Mites: Psoroptes bovis, Sarcoptes scabiei var bovis

Sucking Lice: , and Solenopotes capillatus

Noromectin Multi Injection may also be used as an aid in the control of the biting louse Damalinia bovis and the mange mite Chorioptes bovis, but complete elimination may not occur.

Sheep
Noromectin Multi Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, nasal bots and psoroptic mange (sheep scab):

Gastrointestinal roundworms (adults and fourth stage larvae):
Ostertagia circumcincta, O. trifurcata, Haemonchus contortus, Trichostrongylus axei (adults), Trichostrongylus colubriformis, Trichostrongylus vitrinus (adults), Cooperia curticei, Oesophagostomum venulosum, Oesophagostomum columbianum, Nematodirus filicollis, Chabertia ovina, Trichuris ovis (adults)

Inhibited larval stages and benzimidazole resistant strains of Haemonchus contortus and Ostertagia circumcinctaare also controlled.

Lungworms: Dictyocaulus filaria (adults and fourth stage larvae), Protostrongylus rufescens (adults).

Mange Mites: Psoroptes ovis

Nasal Bot: Oestrus ovis (all larval stages)

Pigs
Noromectin Multi Injection is indicated for the treatment and control of the harmful species of gastrointestinal roundworms, lungworms, lice and mange mites of pigs.

Gastrointestinal worms:
Ascaris suum (adults and fourth stage larvae)
Hyostrongylus rubidus (adults and fourth stage larvae)
Oesophagostomum spp (adults and fourth stage larvae)
Strongyloides ransomi (adults and somatic larval stages)

Lungworms: Metastrongylus spp (adults)

Lice: Haematopinus suis

Mange mites: Sarcoptes scabiei var suis

Noromectin Multi Injection may also be used as an aid in the control of adult whipworm (Trichuris suis).

Persistent activity
When cattle have to graze on pasture contaminated with infective larvae of cattle nematodes, treatment with Noromectin Multi Injection at the recommended dose rate controls re-infection with Haemonchus placei, CooperiaTrichostrongylus axei acquired up to 14 days after treatment, Ostertagia ostertagi and Oesophagostomum radiatum acquired up to 21 days after treatment and Dictyocaulus viviparus acquired up to 28 days after treatment.

To obtain optimal benefit from the persistent activity of Noromectin Multi Injection, it is recommended that calves which are set-stocked in their first grazing season should be treated 3, 8 and 13 weeks after the day of turn-out. This can protect the animals from parasitic gastro-enteritis and lungworm disease throughout the grazing season, provided they are set-stocked, all the calves are included in the program, and that no untreated cattle are added to the pasture.
Treated calves should always be monitored according to good husbandry practices.

Dosage Admin: Cattle Noromectin Multi Injection should be given only by subcutaneous injection at the recommended dosage level of 200 ug ivermectin per kilogram bodyweight. Each ml contains 10 mg of ivermectin sufficient to treat 50 kg of bodyweight. Use the following dosage schedule. Bodyweight (kg) Dose Volume (ml) Up to 50 1.0 51 to 100 2.0 101 to 150 3.0 151 to 200 4.0 201 to 250 5.0 251 to 300 6.0 301 to 350 7.0 351 to 400 8.0 401 to 450 9.0 451 to 500 10.0 501 to 550 11.0 551 to 600 12.0 Noromectin Multi Injection is to be given subcutaneously only. Inject under the loose skin in front of or behind the shoulder. Use of a 17 gauge x ½ inch (15-20 mm) needle is suggested. Replace with a fresh sterile needle after every 10-12 animals. Injection of animals with wet or dirty hides is not recommended. Sheep Noromectin Multi Injection should be given only by subcutaneous injection at the recommended dosage level of 200 g ivermectin per kilogram bodyweight (0.5 ml per 25 kg bodyweight). Each ml contains 10 mg ivermectin to treat 50 kg bodyweight. Noromectin Multi Injection is to be given subcutaneously only. Inject once under the loose skin in the neck. For the treatment and control of sheep scab (Psoroptes ovis) two injections with a seven day interval are required to treat clinical signs of scab and eliminate living mites. Use of a 17 gauge x ½ inch (15-20 mm) needle is suggested. Replace with a fresh sterile needle after every 10-12 animals. Injection of wet or dirty animals is not recommended. When treating sheep of less than 16 kg seek veterinary advice regarding the use of 1 ml disposable syringes graduated in increments of 0.1 ml. For the treatment of individual sheep a syringe not exceeding 2.0 ml and calibrated in increments of 0.1 ml should be used. Use the following dosage schedule: Bodyweight (kg) Dose Volume (ml) Up to 5 0.1 5.1 to 10 0.2 10.1 to 15 0.3 15.1 to 25 0.5 25.1 to 50 1.0 50.1 to 75 1.5 75.1 to 100 2.0 Pigs Noromectin Multi Injection should be given only by subcutaneous injection in the neck at the recommended dosage level of 300 ug ivermectin per kilogram bodyweight (1 ml per 33 kg bodyweight). Use the following dosage schedule. In young pigs, especially those weighing under 16 kg for which less than 0.5 ml of Noromectin is indicated, dosing accuracy is important. The use of a syringe that can accurately deliver 0.1 ml is recommended. For piglets weighing less than 16 kg the product should be given at 0.1 ml per 3 kg. Bodyweight (kg) Dose Volume (ml) 17 to 33 1.0 34 to 50 1.5 51 to 66 2.0 67 to 99 3.0 100 to 133 4.0 134 to 166 5.0 167 to 200 6.0 Over 200 kg bodyweight give 1.0 ml per 33 kg bodyweight. MODE OF ACTION Ivermectin paralyses and ultimately kills parasitic nematodes, arachnids and insects by its effect on the nervous system of these parasites. At therapeutic doses, ivermectin has no adverse effect on cattle since it does not readily penetrate their central nervous systems. Ivermectin belongs to the avermectin class of anthelmintic endectocides. WHEN TO USE NOROMECTIN MULTI INJECTION The suggested dosing programme has been developed to make the best use of the properties of Noromectin Multi Injection. Your veterinary surgeon will be able to provide further advice. Cattle Stomach and Gut Roundworms Roundworm larvae may survive on the pasture over the winter in great numbers. They infect grazing cattle immediately after turnout, maturing into egg laying worms and causing increased pasture contamination. Early season treatment with Noromectin Multi Injection keeps down the population of worms in your stock and reduces the number of worm eggs passed onto the pasture to cause later infection. Where young cattle are set-stocked, treatments with Noromectin Multi Injection 3, 8 and 13 weeks after an April/May turnout will give season long control of parasitic gastro-enteritis and parasitic bronchitis. Where clean pasture will be available during the summer, give a summer treatment with Noromectin Multi Injection and move stock to the clean pasture within two weeks of treatment. If stock are introduced to pasture contaminated by cattle grazing earlier in the year, it is advisable to continue treating with Noromectin Multi Injection at regular 5-6 weekly intervals to prevent the build up of worm parasites. Ostertagia larvae picked up from the pasture in late summer and early autumn can remain dormant in the stomach wall for many months. In late winter or spring they resume development, resulting in serious disease. Autumn treatment with Noromectin Multi Injection kills these larvae, and prevents Type II ostertagiasis. Lungworm Outbreaks of husk (hoose) are most common in summer and autumn. Routine treatment with Noromectin Multi Injection for stomach and gut roundworm control, e.g. at 3 weeks, 8 weeks, and 13 weeks after turnout can be used to control lungworm infection. Where outbreaks of husk occur, treat promptly with Noromectin Multi Injection and move stock to clean pasture within 2 weeks of treatment. However, note that lungworm larvae can survive in soil for up to a year or more, and it may be difficult to ensure that the pasture is 'clean'. If clean pastures are unavailable, treatments at 6 weekly intervals should control lungworm until housing. Eyeworms The presence of these worms may produce irritation and excessive tear formation in the eye. These tears attract flies which are responsible for the transmission of infection to other cattle. The eyeworms are present throughout the year but transmission from one animal to another, and the annoyance caused by the flies, occurs only during the summer months. Treatment with Noromectin Multi Injection controls adult eyeworms in cattle at any time of the year. Lice and Mites Autumn treatment with Noromectin Multi Injection controls sucking lice, sarcoptic and psoroptic mange mites as infections start to build up. Noromectin Multi Injection may also be used as an aid in the control of biting lice and chorioptic mange mites, but complete elimination may not occur. Treat all animals in contact with each other to prevent cross-infection. Warbles The best time to treat is in autumn or early winter, when Noromectin Multi Injection stops the small migrating larvae before they have time to cause serious damage. Treatment with Noromectin Multi Injection kills all stages of warble larvae and may be given whenever convenient for the farmer. In spring, warbles show as lumps on the backs of previously untreated cattle. Treatment with Noromectin Multi Injection kills these larvae, thus further reducing the population of adult flies for next season. Pigs Breeding Animals At the time of initiating any parasite control programme, it is important to treat all breeding animals in the herd. After the initial treatment use Noromectin Multi Injection regularly as follows: Sows Treat preferably 7-14 days prior to farrowing, to minimise infection of piglets. Gilts Treat 7-14 days prior to service. Treat 7-14 days prior to farrowing. Boars Treat at least twice per year. The above programme is a guide for effective parasite control using Noromectin Multi Injection. Alternatively a wide measure of control may be achieved by "total herd treatment" at six-monthly intervals. Fatteners All pigs received for fattening should be treated before placement in clean quarters. Note 1 For effective mange control, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities. Note 2 Since louse eggs are unaffected by ivermectin and may take up to 3 weeks to hatch, complete elimination may not occur following a single injection.

Do not eat, drink or smoke while handling the product. Direct contact of the product with the skin should be kept to a minimum. Wash hands after use.
Take care to avoid self-injection: the product may cause irritation and/or pain at the site of injection.
When the container is broached (opened) for the first time, using the in-use shelf-life which is specified on this package insert, the date on which any product remaining in the container should be discarded should be worked out. This discard date should be written in the space provided on the label.

For Animal Treatment Only.
Keep out of reach of children.

Cattle must not be slaughtered for human consumption until 35 days after the last treatment.
Do not use in cattle producing milk for human consumption. Do not use in non-lactating dairy cows including pregnant heifers within 60 days of calving.

Pigs must not be slaughtered for human consumption until 28 days after the last treatment.

Sheep must not be slaughtered for human consumption until 42 days after the last treatment.
Do not use in lactating ewes producing milk for human consumption.
Treatment of psoroptic mange (sheep scab) with one injection is not recommended, because although a clinical improvement may be seen, elimination of all mites may not occur.
Sheep scab (Psoroptes ovis) is an extremely contagious external parasite of sheep. Following treatment of infected sheep, great care must be taken to avoid re-infestation, as mites may be viable for up to 15 days off the sheep. It is important to ensure all sheep which have been in contact between treated infected and non-treated non-infected flocks must be avoided until at least 7 days after the last treatment.

This product is for subcutaneous administration only and should not be given via other routes.
Noromectin Multi Injection is a low volume product for cattle, sheep and pigs: it should not be used in other species as adverse reactions, such as fatalities in dogs, may occur.

Transitory discomfort has been observed in some cattle following subcutaneous administration. Tissue swellings at the injection site have been observed. These reactions resolve without treatment. Further information is available upon request. Immediately following injection activity suggesting pain, sometimes intense but usually transient has been observed in some sheep.

EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate ponds, waterways or ditches with product or used container.
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

This product does not contain any antimicrobial preservative. Swab septum before removing each dose. Use a dry sterile needle and syringe. When using the 250 ml, 500 ml and 1 litre pack sizes, use only automatic syringe equipment. To refill the syringe use of a draw-off needle is recommended to avoid excess broaching of the stopper. Protect from light. Do not store above 25*C. Following withdrawal of the first dose, use the product within 28 days. Discard unused material. Avoid introduction of contamination. Keep out of reach of children.

POM-VPS
Ivermectin belongs to the avermectin [3-AV] class of anthelmintics in the endectocides. Chemical group of anthelmintic endectocides. [3-AV]

50 ml, 100 ml, 250 ml, 500 ml and 1 litre containers.

Manufactured by:
Norbrook Laboratories Limited
Newry, Co. Down
Northern Ireland

Distributed by:
Norbrook Laboratories (GB) Limited
The Green
Great Corby
Carlisle, CA4 8LR
England

Vm 02000/4174

Noromectin Multi Injection 300ml