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Norodine 24 Injection 100ml |
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Norodine 24 is indicated in the treatment of acute, subacute and chronic conditions of bacterial origin in horses, cattle, sheep, pigs, dogs and cats. The therapeutic spectrum includes both Gram-negative and Gram-positive bacteria including Streptococci, Staphylococci, Actinobacilli, Actinomycae, Salmonella, Pasteurella, Pneumococci, Proteus, E. coli, Corynebacteria, Vibrio, Bordetella, Brucella, Klebsiellae and Haemophilae. It is also indicated in species where there may be an existing antibiotic drug resistance.
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A clear yellow aqueous solution for parenteral administration containing as active ingredients per ml Sulphadiazine BP 200 mg and Trimethoprim BP 40 mg. Preservative: Chlorocresol 1 mg/ml.
Norodine 24 is indicated in the treatment of acute, subacute and chronic conditions of bacterial origin in horses, cattle, sheep, pigs, dogs and cats. The therapeutic spectrum includes both Gram-negative and Gram-positive bacteria including Streptococci, Staphylococci, Actinobacilli, Actinomycae, Salmonella, Pasteurella, Pneumococci, Proteus, E. coli, Corynebacteria, Vibrio, Bordetella, Brucella, Klebsiellae and Haemophilae. It is also indicated in species where there may be an existing antibiotic drug resistance. Norodine 24 may be administered in respiratory infections of bacterial origin including rhinitis, pneumonia, bronchitis and in bacterial infections secondary to viral disease such as viral pneumonia or mycoplasma infections. It is also indicated in urogenital tract infections (cystitis, vaginitis, urethritis, nephritis and metritis) and alimentary tract infections (including neonatal diarrhoea and salmonellosis). Other infections include foul-in-the-foot, severe mastitis, bacterial agalactia of sows, and infections of eye, ear and mouth.
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For cattle, sheep and pigs the dose is 1 ml per 16 kg bodyweight daily by intramuscular or slow intravenous injection. Norodine 24 may be administered by intravenous injection when rapid blood levels of sulphadiazine and trimethoprim are required. For horses the dose is 1 ml per 16 kg bodyweight by slow intravenous injection. For dogs and cats 1 ml per 8 kg bodyweight, by subcutaneous injection only. The recommended site in dogs is the loose skin at the top of the neck. A single injection may be sufficient in uncomplicated conditions, but in severe infections it may be repeated for up to 5 days, or until 2 days after the symptoms resolve. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.
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Injections should not be given by routes other than those recommended. Not to be administered intraperitoneally. Norodine 24 is contra-indicated in animals with known sulphonamide sensitivity, severe liver parenchymal damage, or blood dyscrasias. Milk for human consumption must not be taken from a cow during treatment. Milk for human consumption may only be taken after 48 hours from the last treatment. Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 12 days from the last treatment. Pigs may be slaughtered for human consumption only after 20 days from the last treatment. Adequate drinking water should be available during the therapeutic effect of the product. This product should not be used in horses intended for human consumption. Do not administer to horses exhibiting drug-induced cardiac arrhythmias. Such arrhythmias may be associated with the administration of certain anaesthetic and sedative agents. Anaphylactic shock, potentially fatal, has been observed on rare occasions following administration of potentiated sulphonamide preparations, particularly by the intravenous route. Veterinary surgeons should be mindful of this possibility during the injection process. For intravenous administration the product should be warmed to body temperature and injected slowly over as long a period as is reasonably practical. At the first sign of intolerance the injection should be interrupted and shock treatment initiated. Care must be taken to avoid accidental self-injection.
Store below 25oC. Do not freeze. Crystallisation of the product at low temperatures can be reversed by gentle warming. Protect from light. Keep out of the reach of children. Following withdrawal of the first dose, use the product within 28 days. Discard unused material. For animal treatment only.
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POM-V
Bottles of 50 ml and 100 ml.
Norbrook Laboratories Ltd
Vm 02000/4061
Dispose of any unused product or containers in accordance with guidance from your local waste regulation authority.
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