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Midrid Capsules pack of 15 |
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Midrid is a treatment for migraine and throbbing headaches. The active ingredients in Midrid each work in a different way to stop the pain. The throbbing pain sometimes felt during a migraine is linked to swollen blood vessels (vasodilation) in the head. Paracetamol works directly on the pain, whereas isometheptene returns the blood vessels to normal and as a result helps to take away the pain.
Patient Information Leaflets (PILs):
Midrid
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Paracetamol 325.0mg
Isometheptene mucate 65.0mg
In the treatment of migraine and other vascular headaches
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For oral administration
Adults: 2 capsules at once, then 1 capsule every hour until relief obtained up to a maximum of 5 capsules within a 12 hour period
Children: Not recommended
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Severe cardiac, hepatic or renal impairment, severe hypertension, glaucoma. Patients on monoamine oxidase inhibitor therapy. Porphyria. Hypersensitivity to paracetamol and/or other constituents.
Cardiovascular disease, diabetes mellitus, hyperthyroidism. When used in patients with high spinal cord lesions, isometheptene, like other sympathomimetics may cause autonomic dysreflexia.
Care is advised in the administration of this product to patients with renal or hepatic impairment. The hazards of paracetamol overdose are greater in those with non-cirrhotic alcoholic liver disease.
Do not exceed the recommended dose
If symptoms persist, consult your doctor
Keep out of the sight and reach of children
Patient information leaflet warning
Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.
Label warning
Do not take with any other paracetamol-containing products. Immediate medical advice should be sought in the event of an overdose, even if you feel well.
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Transient dizziness may appear in hypersensitive patients. This can usually be eliminated by reducing the dose. Circulatory disturbances may occur.
Adverse effects of paracetamol are rare but hypersensitivity reactions including skin rashes may occur. Anaphylaxis, angioedema, urticaria and very rare cases of fixed drug eruption have been reported. There have been reports of blood dyscrasias including thrombocytopenia, purpura and agranulocytosis, but these were not necessarily causally related to paracetamol.
Blood disorders have also been reported with isometheptene containing products.
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